ID A0A8J3QJY7_9ACTN Unreviewed; 582 AA.
AC A0A8J3QJY7;
DT 25-MAY-2022, integrated into UniProtKB/TrEMBL.
DT 25-MAY-2022, sequence version 1.
DT 28-JAN-2026, entry version 19.
DE RecName: Full=Selenocysteine-specific elongation factor {ECO:0000256|ARBA:ARBA00015953};
DE AltName: Full=SelB translation factor {ECO:0000256|ARBA:ARBA00031615};
GN Name=selB {ECO:0000313|EMBL:GIH10521.1};
GN ORFNames=Rhe02_85880 {ECO:0000313|EMBL:GIH10521.1};
OS Rhizocola hellebori.
OC Bacteria; Bacillati; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Rhizocola.
OX NCBI_TaxID=1392758 {ECO:0000313|EMBL:GIH10521.1, ECO:0000313|Proteomes:UP000612899};
RN [1] {ECO:0000313|EMBL:GIH10521.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NBRC 109834 {ECO:0000313|EMBL:GIH10521.1};
RA Komaki H., Tamura T.;
RT "Whole genome shotgun sequence of Rhizocola hellebori NBRC 109834.";
RL Submitted (JAN-2021) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Translation factor necessary for the incorporation of
CC selenocysteine into proteins. It probably replaces EF-Tu for the
CC insertion of selenocysteine directed by the UGA codon. SelB binds GTP
CC and GDP. {ECO:0000256|ARBA:ARBA00025526}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GIH10521.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BONY01000097; GIH10521.1; -; Genomic_DNA.
DR RefSeq; WP_203914249.1; NZ_BONY01000097.1.
DR AlphaFoldDB; A0A8J3QJY7; -.
DR Proteomes; UP000612899; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:TreeGrafter.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0001514; P:selenocysteine incorporation; IEA:InterPro.
DR CDD; cd04171; SelB; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR057335; Beta-barrel_SelB.
DR InterPro; IPR050055; EF-Tu_GTPase.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR015191; SelB_WHD4.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR004535; Transl_elong_SelB.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR NCBIfam; TIGR00475; selB; 1.
DR PANTHER; PTHR43721:SF22; ELONGATION FACTOR TU, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43721; ELONGATION FACTOR TU-RELATED; 1.
DR Pfam; PF25461; Beta-barrel_SelB; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR Pfam; PF09107; WHD_3rd_SelB; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Elongation factor {ECO:0000313|EMBL:GIH10521.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00023134};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000612899}.
FT DOMAIN 1..168
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
SQ SEQUENCE 582 AA; 61667 MW; FC774EAF7C951F02 CRC64;
MYVIATAGHV DHGKSALLRA LTGMEPDRWE EEQRRGLTID LGFVWTQGRH GSLAFVDVPG
HERFVGNMLA GVGPVPAVLF VVAADEGWMP QSAEHLTALH ALGVRHGLLA ITKADLMEPE
LAAEEALAEI GQTSLGDIDW LAVSARTGEG LDRLRDKLDD LVAGLPPSDP AAPVRLWADR
AFTIRGAGLV VTGTLAAGSI RVGDTLELAR NEKRFVVREL QSMGERVGEA SGVARVAVNL
RGAHREDIHR GDALMTPGSY RLASLIDVRT RLCVPAELPP QVLVHIGAAT VGGRIRPLGP
DTARLTLAEA LPLRVGDHLV LRHDRGVAGG AVVLDADPAG FQRRGAARLR AEELSGYADL
PDAMEELRRR GVVREATLRA IGVTPPVAPL AADWLMAPDL ADALRERLAA LIAQRAADPA
AAPLKVEEAR KALELPDPRL VVPLLAPGLL VRDGMIIPAE APDTLAPAVR EALAQLETRW
ADRGLETPDL AAFGLGPAEI AASVRSGRLV RLAPDIVLLP AAVTAAIAVL AGLPQPFTAG
EAREALSTSR KIVVPLLEHT ATQGLTRRQS DGRHTISAPF AA
//
