ID A0A8J3TCN9_9ACTN Unreviewed; 589 AA.
AC A0A8J3TCN9;
DT 25-MAY-2022, integrated into UniProtKB/TrEMBL.
DT 25-MAY-2022, sequence version 1.
DT 28-JAN-2026, entry version 19.
DE RecName: Full=Selenocysteine-specific elongation factor {ECO:0000256|ARBA:ARBA00015953};
DE AltName: Full=SelB translation factor {ECO:0000256|ARBA:ARBA00031615};
GN Name=selB {ECO:0000313|EMBL:GII23086.1};
GN ORFNames=Pme01_26830 {ECO:0000313|EMBL:GII23086.1};
OS Planosporangium mesophilum.
OC Bacteria; Bacillati; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Planosporangium.
OX NCBI_TaxID=689768 {ECO:0000313|EMBL:GII23086.1, ECO:0000313|Proteomes:UP000599074};
RN [1] {ECO:0000313|EMBL:GII23086.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NBRC 109066 {ECO:0000313|EMBL:GII23086.1};
RA Komaki H., Tamura T.;
RT "Whole genome shotgun sequence of Planosporangium mesophilum NBRC 109066.";
RL Submitted (JAN-2021) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Translation factor necessary for the incorporation of
CC selenocysteine into proteins. It probably replaces EF-Tu for the
CC insertion of selenocysteine directed by the UGA codon. SelB binds GTP
CC and GDP. {ECO:0000256|ARBA:ARBA00025526}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GII23086.1}.
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DR EMBL; BOON01000024; GII23086.1; -; Genomic_DNA.
DR RefSeq; WP_168115705.1; NZ_BOON01000024.1.
DR AlphaFoldDB; A0A8J3TCN9; -.
DR Proteomes; UP000599074; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:TreeGrafter.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0001514; P:selenocysteine incorporation; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR057335; Beta-barrel_SelB.
DR InterPro; IPR050055; EF-Tu_GTPase.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR015191; SelB_WHD4.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR004535; Transl_elong_SelB.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR00475; selB; 1.
DR PANTHER; PTHR43721:SF22; ELONGATION FACTOR TU, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43721; ELONGATION FACTOR TU-RELATED; 1.
DR Pfam; PF25461; Beta-barrel_SelB; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR Pfam; PF09107; WHD_3rd_SelB; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Elongation factor {ECO:0000313|EMBL:GII23086.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00023134};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000599074}.
FT DOMAIN 1..167
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
SQ SEQUENCE 589 AA; 61591 MW; A7E2C4F2293FA9F5 CRC64;
MHVIATAGHV DHGKSTLVRA LTGMEPDRWA EERRRGMTID LGFAWTTLGS GEVVAFVDVP
GHERFVPNML AGIGPVPAAL VVVAADEGWM PQSAEHLAAL NALGVSHGLL VVTRSDLFDP
ALATAEAQEQ IAATSLGAVD AVAVSAVTGA GLDDLRAALD ALVARLPAPD RDAPVRLWVD
RSFTIRGAGT VVTGTLGAGR LRPNDELELA ASGRPVRVRG LQSLGAPVAE AAAVARVAVN
LRGIERDEVG RGDALVTPGR FHRTDVVDVR LAGDPVADLP STLTLHVGSA AVAVRIRPLG
VDTARLRLDA ALPLRVGDRA LLRDPGRHHV AGGVTVLDVS PPPLRRRGAA AARARELSTM
DGVPSQSDEL RRRGLVRRPE LERMGVPAAG TPVAGDWLAD PDHWSALRKR LAEEVADYAR
DHPLETGAPV DALRHALGLP DRALVDALVA PPLTARSGRI AQAGQGSSLP GPVADAVDRV
RADLEGDPFR APEAARLAEL GLGPRELAAA VRAGALVRVA DGVVLLPGAL DEAVAVLSRV
SQPFTLSDAR QALGTSRRVA VPLLEMLDRS GATRRLPDDR RVVAGEVDG
//
