ID A0A8J4KLW0_EUDCH Unreviewed; 384 AA.
AC A0A8J4KLW0;
DT 25-MAY-2022, integrated into UniProtKB/TrEMBL.
DT 25-MAY-2022, sequence version 1.
DT 18-JUN-2025, entry version 14.
DE RecName: Full=RBR-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012251};
DE EC=2.3.2.31 {ECO:0000256|ARBA:ARBA00012251};
DE Flags: Fragment;
GN Name=Arih1 {ECO:0000313|EMBL:KAF1644460.1};
GN ORFNames=FQV12_0010849 {ECO:0000313|EMBL:KAF1644460.1};
OS Eudyptes chrysocome (Western rockhopper penguin) (Aptenodytes chrysocome).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Neoaves; Aequornithes; Sphenisciformes;
OC Spheniscidae; Eudyptes.
OX NCBI_TaxID=79626 {ECO:0000313|EMBL:KAF1644460.1, ECO:0000313|Proteomes:UP000716595};
RN [1] {ECO:0000313|EMBL:KAF1644460.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=RH 110-1 {ECO:0000313|EMBL:KAF1644460.1};
RX PubMed=31531675; DOI=10.1093/gigascience/giz117;
RA Pan H., Cole T.L., Bi X., Fang M., Zhou C., Yang Z., Ksepka D.T., Hart T.,
RA Bouzat J.L., Argilla L.S., Bertelsen M.F., Boersma P.D., Bost C.A.,
RA Cherel Y., Dann P., Fiddaman S.R., Howard P., Labuschagne K., Mattern T.,
RA Miller G., Parker P., Phillips R.A., Quillfeldt P., Ryan P.G., Taylor H.,
RA Thompson D.R., Young M.J., Ellegaard M.R., Gilbert M.T.P., Sinding M.S.,
RA Pacheco G., Shepherd L.D., Tennyson A.J.D., Grosser S., Kay E., Nupen L.J.,
RA Ellenberg U., Houston D.M., Reeve A.H., Johnson K., Masello J.F.,
RA Stracke T., McKinlay B., Borboroglu P.G., Zhang D.X., Zhang G.;
RT "High-coverage genomes to elucidate the evolution of penguins.";
RL Gigascience 8:0-0(2019).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.;
CC EC=2.3.2.31; Evidence={ECO:0000256|ARBA:ARBA00001798};
CC -!- SIMILARITY: Belongs to the RBR family. Ariadne subfamily.
CC {ECO:0000256|ARBA:ARBA00005884}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAF1644460.1}.
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DR EMBL; VULL01002314; KAF1644460.1; -; Genomic_DNA.
DR Proteomes; UP000716595; Unassembled WGS sequence.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016567; P:protein ubiquitination; IEA:InterPro.
DR CDD; cd20343; BRcat_RBR_HHARI-like; 1.
DR CDD; cd20356; Rcat_RBR_HHARI-like; 1.
DR CDD; cd16626; RING-HC_RBR_HHARI; 1.
DR FunFam; 1.20.120.1750:FF:000002; RBR-type E3 ubiquitin transferase; 1.
DR FunFam; 3.30.40.10:FF:000019; RBR-type E3 ubiquitin transferase; 1.
DR Gene3D; 1.20.120.1750; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR045840; Ariadne.
DR InterPro; IPR031127; E3_UB_ligase_RBR.
DR InterPro; IPR002867; IBR_dom.
DR InterPro; IPR044066; TRIAD_supradom.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR11685; RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING; 1.
DR Pfam; PF19422; Ariadne; 1.
DR Pfam; PF01485; IBR; 1.
DR Pfam; PF22191; IBR_1; 1.
DR Pfam; PF13923; zf-C3HC4_2; 1.
DR SMART; SM00647; IBR; 2.
DR SMART; SM00184; RING; 2.
DR SUPFAM; SSF57850; RING/U-box; 3.
DR PROSITE; PS51873; TRIAD; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000716595};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 35..246
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS51873"
FT DOMAIN 39..87
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KAF1644460.1"
FT NON_TER 384
FT /evidence="ECO:0000313|EMBL:KAF1644460.1"
SQ SEQUENCE 384 AA; 45222 MW; F85949E484B21452 CRC64;
RYFDGNLEKL FAECHVINPS KKSRTRQMNT RSSAQDMPCQ ICYLNYPNSY FTGLECGHKF
CMQCWSEYLT TKIMEEGMGQ TISCPAHGCD ILVDDNTVMR LITDSKVKLK YQHLITNSFV
ECNRLLKWCP APDCHHVVKV QYPDAKPVRC KCGRQFCFNC GENWHDPVKC KWLKKWIKKC
DDDSETSNWI AANTKECPKC HVTIEKDGGC NHMVCRNQNC KAEFCWVCLG PWEPHGSAWY
NCNRYNEDDA KAARDAQERS RAALQRYLFY CNRYMNHMQS LRFEHKLYAQ VKQKMEEMQQ
HNMSWIEVQF LKKAVDVLCQ CRATLMYTYV FAFYLKKNNQ SIIFENNQAD LENATEVLSG
YLERDISQDS LQDIKQKVQD KYRF
//
