ID A0A8J6KLG8_MICOH Unreviewed; 708 AA.
AC A0A8J6KLG8;
DT 25-MAY-2022, integrated into UniProtKB/TrEMBL.
DT 25-MAY-2022, sequence version 1.
DT 28-JAN-2026, entry version 11.
DE RecName: Full=Zinc finger protein 750 {ECO:0000256|ARBA:ARBA00040216};
GN ORFNames=LTLLF_194890 {ECO:0000313|EMBL:KAH0501773.1};
OS Microtus ochrogaster (Prairie vole).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Arvicolinae; Microtus.
OX NCBI_TaxID=79684 {ECO:0000313|EMBL:KAH0501773.1, ECO:0000313|Proteomes:UP000710432};
RN [1] {ECO:0000313|EMBL:KAH0501773.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=LTLLF {ECO:0000313|EMBL:KAH0501773.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:KAH0501773.1};
RA Glass D.;
RT "Studies in the Genomics of Life Span.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAH0501773.1}.
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DR EMBL; JAATJU010026385; KAH0501773.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A8J6KLG8; -.
DR Proteomes; UP000710432; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IEA:TreeGrafter.
DR GO; GO:1990841; F:promoter-specific chromatin binding; IEA:TreeGrafter.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:TreeGrafter.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0008544; P:epidermis development; IEA:TreeGrafter.
DR InterPro; IPR039363; ZNF750.
DR InterPro; IPR039064; ZNF750_Znf.
DR PANTHER; PTHR14678; PROLINE-RICH PROTEIN 35-RELATED; 1.
DR PANTHER; PTHR14678:SF1; ZINC FINGER PROTEIN 750; 1.
DR Pfam; PF15269; zf-C2H2_7; 1.
PE 4: Predicted;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW Differentiation {ECO:0000256|ARBA:ARBA00022782};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 6..57
FT /note="Zinc finger protein 750-like zinc finger"
FT /evidence="ECO:0000259|Pfam:PF15269"
FT REGION 63..112
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 350..514
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 553..617
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 630..708
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 67..81
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 90..106
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 352..361
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 367..394
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 410..421
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 456..493
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 579..616
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 643..662
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 708 AA; 77082 MW; 0079923CB6C5E8D6 CRC64;
MSLLKERKPK KPHYIPRPPG KPFKYKCFQC PFTCNEKSHL FNHMKYGLCK NSITLVSEQD
RIPKCPKSSS LDPKQTHQPD PTSKPAASKS LPNGLSSFDP KSQQGSTKED AKENLEMQAR
GTHKGPQKPI LQKEVTPEAI LSTQLDSGVR PSAFVPVGEH RLRGPEDTEA PEMLALTNST
TKATSFHAKS AFHTPGYPWK AGSPFLPPDF PHKIPSTKGF GAISPYMHPA IPEYPHPFYT
EHGLAAIYSP YLLTGNTPEC EATLLSVYGS QDQRHFLSHP GPIPKHLNTT PSTYDHYRFF
QQYHSNLPIP YGFYRPESAF PPYGLRLPPV PGITRDQSSR LLEEAALAYP ASSPSELNLS
NSHKKHTEFE KESPLPEAKD PSKDGQRDAE EAKMSPRAGS AATGSPGRPS PTNFTQTSQT
FEGLCDLSNK AASSGTPERL QQPEQSPTAF KPVQRGSESP QSQPPASRTE SPKSLQVMNS
DSLAQTGTST SLITEAPPSS PEDHSRISPL NLSKKLETNP AATYGPMYVD NAQADALGFS
GLQDLPLNLS VKDPCNAWAP RPVFPSPPQG AEPAAALKTE TKGSEDRTSP VETQEDKAHG
RTAPDAHTVD SSDEQKQTAA VALCQLAAYS PGKVRVGDEE GTVQESTGQD GPTLGSTENQ
GAQCDLRPKG QKRTSQRDAG KSQQGTKKPR LNDTIPRVLT LRKRTRVS
//
