ID A0A8K0HFE1_9ROSA Unreviewed; 943 AA.
AC A0A8K0HFE1;
DT 03-AUG-2022, integrated into UniProtKB/TrEMBL.
DT 03-AUG-2022, sequence version 1.
DT 28-JAN-2026, entry version 14.
DE RecName: Full=Disease resistance protein RGA3 {ECO:0008006|Google:ProtNLM};
GN ORFNames=FNV43_RR06884 {ECO:0000313|EMBL:KAF3450795.1};
OS Rhamnella rubrinervis.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Rhamnaceae; rhamnoid group; Rhamneae; Rhamnella.
OX NCBI_TaxID=2594499 {ECO:0000313|EMBL:KAF3450795.1, ECO:0000313|Proteomes:UP000796880};
RN [1] {ECO:0000313|EMBL:KAF3450795.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=BYM {ECO:0000313|EMBL:KAF3450795.1};
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF3450795.1};
RA Lu Z., Yang Y., Zhu X., Sun Y.;
RT "A high-quality chromosome-level genome assembly of a woody plant with both
RT climbing and erect habits, Rhamnella rubrinervis.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAF3450795.1}.
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DR EMBL; VOIH02000003; KAF3450795.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A8K0HFE1; -.
DR OrthoDB; 5279713at2759; -.
DR Proteomes; UP000796880; Unassembled WGS sequence.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0051707; P:response to other organism; IEA:UniProtKB-ARBA.
DR CDD; cd14798; RX-CC_like; 1.
DR FunFam; 3.40.50.300:FF:001091; Probable disease resistance protein At1g61300; 1.
DR FunFam; 1.10.10.10:FF:000322; Probable disease resistance protein At1g63360; 1.
DR Gene3D; 1.20.5.4130; -; 1.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR055414; LRR_R13L4/SHOC2-like.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038005; RX-like_CC.
DR InterPro; IPR041118; Rx_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR058922; WHD_DRP.
DR PANTHER; PTHR36766:SF45; NB-ARC DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR36766; PLANT BROAD-SPECTRUM MILDEW RESISTANCE PROTEIN RPW8; 1.
DR Pfam; PF23598; LRR_14; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF18052; Rx_N; 1.
DR Pfam; PF23559; WHD_DRP; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM00369; LRR_TYP; 2.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51450; LRR; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW Reference proteome {ECO:0000313|Proteomes:UP000796880};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 6..92
FT /note="Disease resistance N-terminal"
FT /evidence="ECO:0000259|Pfam:PF18052"
FT DOMAIN 197..351
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
FT DOMAIN 436..507
FT /note="Disease resistance protein winged helix"
FT /evidence="ECO:0000259|Pfam:PF23559"
FT DOMAIN 565..896
FT /note="Disease resistance R13L4/SHOC-2-like LRR"
FT /evidence="ECO:0000259|Pfam:PF23598"
FT COILED 28..55
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 943 AA; 108437 MW; 35BAC81C6CCC87C6 CRC64;
MADAMVSVLL DHFVSIVREQ VEENVKLVMG VEKEVENLNS NLKAIQAVLE DAEKRQLSED
SVRLWLEELK EASYDILDVL DEWSTNVNSI DHSEITKKKV CFSFLFPCFA SRQLGQVGFR
YEIGSNIRKL NGKLQDIAIR KDMYNFKATK GVDEPDQRPK TTSIIDVSEV RGRDEEKRNL
VRKLLSNRIS PDGIGRNLNI VPVVGMGGIG KTTLAQLAYN DGNVKTHFDL KIWVCVSNPF
DEVRVAKAII EQLTGQATTL VEHEALLRSI LNSIEYKKFL LVLDDVWTED YQKWEPLKQT
LKYGAVGSRI LVTTRKKKVA MMMGEPEHMI SLKELSEEDC WLLFSQVAFL GRDEEERELL
EGIGRQIASK CKGLPLAAKT LGSFMRFKRT KQQWEDVLHN DIWDLEEARR DLFSPLLLSY
YDLSPTVKRC FSYCAIFPKD ELIDKDDLIQ QWMSQGYLSL KKNRDMEITG RECFDNLAMR
SFFQDFIKDE DGNILKCKMH DIMHDFAQDL TRNEFSITEI KGFELEERGG SIKNARHLTL
MLEPDAHIPV STLKRKNLHT LLVSGSNIAA ISPDHFQHLT RLRTLNLSGC SIQQLPQNIG
ELVHLRYLNL SYNLLEELPR TIGKLRNLQT LRLECCSRLQ RLPETIGEAT GLRHLYVSGC
PLLDHLPCEV CCLSSLRTMD VFIVPDFKNY GNMSCSLEGL RSLNYLQRIY INGLGNAPMW
TVSKANLYNK KNLRELSLDF RTGTDTEIQE KQHEVLLRLI PHRNLETLRI LDYCGGITVF
PIWMMTLTNL RRLVIKNCHF CEELPPLGKL PFLEFLNVLN LDKLKTVGSE FLGIEMDGTS
NAFFCSIVSF PRLKEVKFRC KAWWQWRGIP GWKVEDSPVT IMPRLHSLKF GACKSLEELP
NYLQTVPLQN LIMEECPKLQ KCCQTGTGRE WPKIRHIPNI QMS
//
