ID A0A8K0MZ10_COCNU Unreviewed; 328 AA.
AC A0A8K0MZ10;
DT 03-AUG-2022, integrated into UniProtKB/TrEMBL.
DT 03-AUG-2022, sequence version 1.
DT 10-JUN-2026, entry version 14.
DE RecName: Full=RING-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012483};
DE EC=2.3.2.27 {ECO:0000256|ARBA:ARBA00012483};
GN ORFNames=COCNU_03G011420 {ECO:0000313|EMBL:KAG1335023.1};
OS Cocos nucifera (Coconut palm).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Arecaceae; Arecoideae; Cocoseae;
OC Attaleinae; Cocos.
OX NCBI_TaxID=13894 {ECO:0000313|EMBL:KAG1335023.1, ECO:0000313|Proteomes:UP000797356};
RN [1] {ECO:0000313|EMBL:KAG1335023.1, ECO:0000313|Proteomes:UP000797356}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Hainan Tall {ECO:0000313|Proteomes:UP000797356};
RC TISSUE=Spear leaf of Hainan Tall coconut
RC {ECO:0000313|EMBL:KAG1335023.1};
RX PubMed=29048487;
RA Xiao Y., Xu P., Fan H., Baudouin L., Xia W., Bocs S., Xu J., Li Q., Guo A.,
RA Zhou L., Li J., Wu Y., Ma Z., Armero A., Issali A.E., Liu N., Peng M.,
RA Yang Y.;
RT "The genome draft of coconut (Cocos nucifera).";
RL Gigascience 6:1-11(2017).
RN [2] {ECO:0000313|EMBL:KAG1335023.1, ECO:0000313|Proteomes:UP000797356}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Hainan Tall {ECO:0000313|Proteomes:UP000797356};
RC TISSUE=Spear leaf of Hainan Tall coconut
RC {ECO:0000313|EMBL:KAG1335023.1};
RX PubMed=33483627;
RA Yang Y., Bocs S., Fan H., Armero A., Baudouin L., Xu P., Xu J., This D.,
RA Hamelin C., Iqbal A., Qadri R., Zhou L., Li J., Wu Y., Ma Z., Issali A.E.,
RA Rivallan R., Liu N., Xia W., Peng M., Xiao Y.;
RT "Coconut genome assembly enables evolutionary analysis of palms and
RT highlights signaling pathways involved in salt tolerance.";
RL Commun. Biol. 4:105-105(2021).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.;
CC EC=2.3.2.27; Evidence={ECO:0000256|ARBA:ARBA00000900};
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- SIMILARITY: Belongs to the SINA (Seven in absentia) family.
CC {ECO:0000256|ARBA:ARBA00009119}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAG1335023.1}.
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DR EMBL; CM017874; KAG1335023.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A8K0MZ10; -.
DR OrthoDB; 941555at2759; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000797356; Chromosome 3.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR CDD; cd16571; RING-HC_SIAHs; 1.
DR CDD; cd03829; Sina; 1.
DR FunFam; 3.30.40.10:FF:000041; E3 ubiquitin-protein ligase SINAT3; 1.
DR FunFam; 2.60.210.10:FF:000004; E3 ubiquitin-protein ligase SINAT5-like; 1.
DR Gene3D; 2.60.210.10; Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2, Chain A; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR018121; 7-in-absentia-prot_TRAF-dom.
DR InterPro; IPR052088; E3_ubiquitin-ligase_SINA.
DR InterPro; IPR049548; Sina-like_RING.
DR InterPro; IPR008974; TRAF-like.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR013010; Znf_SIAH.
DR PANTHER; PTHR10315; E3 UBIQUITIN PROTEIN LIGASE SIAH; 1.
DR PANTHER; PTHR10315:SF80; E3 UBIQUITIN-PROTEIN LIGASE SINAT3; 1.
DR Pfam; PF21362; Sina_RING; 1.
DR Pfam; PF03145; Sina_TRAF; 1.
DR Pfam; PF21361; Sina_ZnF; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF49599; TRAF domain-like; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
DR PROSITE; PS51081; ZF_SIAH; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000797356};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00455}.
FT DOMAIN 66..102
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 119..179
FT /note="SIAH-type"
FT /evidence="ECO:0000259|PROSITE:PS51081"
SQ SEQUENCE 328 AA; 36725 MW; CD80DE03889C10C3 CRC64;
MELDNIECIS SLDGMDDDEG AAHQLPNPFL KLHHGGSGNA CGGVGGGGVS APVISPATSV
HELLECPVCT NSMYPPIHQC HNGHTLCSTC KSRVHNRCPT CRQELGDIRC LALEKVAESL
ELPCKYFSLG CPEIFPYYSK LKHEALCNFR PYNCPYAGSE CSVVGDIPFL VSHLRDYHKV
DMHTGCTFNH RYVKSNPREV ENATWMLTVF HCFGQYFCLH FEAFQLGMAP VYMTFLRFMG
DENEARNYSY SLEVGANGRK LTWEGTPRSI RDSHRKVRDS HDGLIIQRNI ALFFSGGDRK
ELKLRVTGRI WKEQPNPDAG VCIPNLCS
//
