ID A0A8M9PKV4_DANRE Unreviewed; 410 AA.
AC A0A8M9PKV4;
DT 03-AUG-2022, integrated into UniProtKB/TrEMBL.
DT 03-AUG-2022, sequence version 1.
DT 28-JAN-2026, entry version 19.
DE SubName: Full=Proteasomal ubiquitin receptor ADRM1 isoform X2 {ECO:0000313|RefSeq:XP_021325529.1};
GN Name=adrm1 {ECO:0000313|RefSeq:XP_021325529.1,
GN ECO:0000313|ZFIN:ZDB-GENE-040426-905};
GN Synonyms=adrm1a {ECO:0000313|RefSeq:XP_021325529.1}, adrm1b
GN {ECO:0000313|RefSeq:XP_021325529.1}, fa12d09
GN {ECO:0000313|RefSeq:XP_021325529.1}, wu:fa10g10
GN {ECO:0000313|RefSeq:XP_021325529.1}, wu:fa12d09
GN {ECO:0000313|RefSeq:XP_021325529.1}, zgc:56107
GN {ECO:0000313|RefSeq:XP_021325529.1}, zgc:77256
GN {ECO:0000313|RefSeq:XP_021325529.1};
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955 {ECO:0000313|Proteomes:UP000000437, ECO:0000313|RefSeq:XP_021325529.1};
RN [1] {ECO:0000313|RefSeq:XP_021325529.1}
RP IDENTIFICATION.
RC STRAIN=Tuebingen {ECO:0000313|RefSeq:XP_021325529.1};
RC TISSUE=Fibroblasts and whole tissue
RC {ECO:0000313|RefSeq:XP_021325529.1};
RG RefSeq;
RL Submitted (AUG-2025) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the ADRM1 family.
CC {ECO:0000256|ARBA:ARBA00009216}.
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DR RefSeq; XP_021325529.1; XM_021469854.3.
DR AlphaFoldDB; A0A8M9PKV4; -.
DR SMR; A0A8M9PKV4; -.
DR GeneID; 796450; -.
DR AGR; ZFIN:ZDB-GENE-040426-905; -.
DR CTD; 11047; -.
DR ZFIN; ZDB-GENE-040426-905; adrm1.
DR Proteomes; UP000000437; Chromosome 23.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
DR CDD; cd13314; PH_Rpn13; 1.
DR FunFam; 1.10.2020.20:FF:000001; Proteasomal ubiquitin receptor ADRM1; 1.
DR FunFam; 2.30.29.70:FF:000001; Proteasomal ubiquitin receptor ADRM1; 1.
DR Gene3D; 1.10.2020.20; -; 1.
DR Gene3D; 2.30.29.70; Proteasomal ubiquitin receptor Rpn13/ADRM1; 1.
DR InterPro; IPR044867; DEUBAD_dom.
DR InterPro; IPR006773; Rpn13/ADRM1.
DR InterPro; IPR044868; Rpn13/ADRM1_Pru.
DR InterPro; IPR038633; Rpn13/ADRM1_Pru_sf.
DR InterPro; IPR032368; RPN13_DEUBAD.
DR InterPro; IPR038108; RPN13_DEUBAD_sf.
DR PANTHER; PTHR12225; ADHESION REGULATING MOLECULE 1 110 KDA CELL MEMBRANE GLYCOPROTEIN; 1.
DR PANTHER; PTHR12225:SF0; PROTEASOMAL UBIQUITIN RECEPTOR ADRM1; 1.
DR Pfam; PF04683; Rpn13_ADRM1_Pru; 1.
DR Pfam; PF16550; RPN13_C; 1.
DR PROSITE; PS51916; DEUBAD; 1.
DR PROSITE; PS51917; PRU; 1.
PE 1: Evidence at protein level;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Proteasome {ECO:0000256|ARBA:ARBA00022942};
KW Proteomics identification {ECO:0007829|PeptideAtlas:A0A8M9PKV4};
KW Receptor {ECO:0000313|RefSeq:XP_021325529.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000437}.
FT DOMAIN 17..130
FT /note="Pru"
FT /evidence="ECO:0000259|PROSITE:PS51917"
FT DOMAIN 281..395
FT /note="DEUBAD"
FT /evidence="ECO:0000259|PROSITE:PS51916"
FT REGION 191..264
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 381..410
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 191..257
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 381..401
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 410 AA; 42596 MW; 0DF487D721BDF6A7 CRC64;
MSSGALFPSL VSGSRSSSSK YLVEFRAGKM TLKGSTVTPD KRKGTVYIQQ TDDSLIHFCW
KDRTSGNVED DLIIFPDDCE FKRVNQCTTG RVYVLKFKAG SKRLFFWMQE PKTDKDDEYC
RKVNEYLNNP PMPGALGSGG GGGHELSALG EGGLQSLLGN MSHNQLMQLI GPTGLGGLGA
LAGPGLASLL GSGGPATSSS TSSSRSQSAA ATPSSGSAAR LSSTQAPTTP VTPAATSSGS
PTVTPTTPAA QTPSLPAGPA SSTQPIQLSD LQSILATMNV PAMPTEGSGV DLASVLTPDV
MAPILANPEV QQRLLPYLPS GESLPQSAEE IQNTLTSPQF QQAMSMFSSA LASGQLGPLM
NQFGLPSEAV DAANKGDVEA FAKAMEGSDS KTDDGDSKDK KDDDEDMSLD
//
