ID A0A8S1KA38_9CILI Unreviewed; 444 AA.
AC A0A8S1KA38;
DT 12-OCT-2022, integrated into UniProtKB/TrEMBL.
DT 12-OCT-2022, sequence version 1.
DT 02-APR-2025, entry version 12.
DE RecName: Full=RBR-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012251};
DE EC=2.3.2.31 {ECO:0000256|ARBA:ARBA00012251};
GN ORFNames=PSON_ATCC_30995.1.T0060527 {ECO:0000313|EMBL:CAD8052580.1};
OS Paramecium sonneborni.
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC Oligohymenophorea; Peniculida; Parameciidae; Paramecium.
OX NCBI_TaxID=65129 {ECO:0000313|EMBL:CAD8052580.1, ECO:0000313|Proteomes:UP000692954};
RN [1] {ECO:0000313|EMBL:CAD8052580.1}
RP NUCLEOTIDE SEQUENCE.
RG Genoscope - CEA;
RA William W.;
RL Submitted (JAN-2021) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.;
CC EC=2.3.2.31; Evidence={ECO:0000256|ARBA:ARBA00001798};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CAD8052580.1}.
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DR EMBL; CAJJDN010000006; CAD8052580.1; -; Genomic_DNA.
DR OrthoDB; 303865at2759; -.
DR Proteomes; UP000692954; Unassembled WGS sequence.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016567; P:protein ubiquitination; IEA:InterPro.
DR CDD; cd22584; Rcat_RBR_unk; 1.
DR FunFam; 3.30.40.10:FF:000894; RBR-type E3 ubiquitin transferase; 1.
DR InterPro; IPR031127; E3_UB_ligase_RBR.
DR InterPro; IPR002867; IBR_dom.
DR InterPro; IPR044066; TRIAD_supradom.
DR PANTHER; PTHR11685; RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING; 1.
DR Pfam; PF01485; IBR; 2.
DR SMART; SM00647; IBR; 2.
DR PROSITE; PS51873; TRIAD; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000692954};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 102..296
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS51873"
FT COILED 305..339
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 444 AA; 52686 MW; 54D57FDB6DAAF4C3 CRC64;
MDEYYDEQYN IGLDEDYDNN DLQKNEILLS QNELYQEFLN RLDKIKDKIG ESPQVILNIL
IFFNFEEQSI YEKLLLDGES DKIKSQLQEQ GIYNESEVKF HENIFCSICE QNGIQGFSLN
CDHKFCQSCW NQMIEIQFSS QIPLVRCLQD QCFERLPNSF LEQYPNYKQI LIKRFMQHDS
SITWCPGLNC ENVFKYLNFS HSIKCPCGIK FCSKCREEKH YPIPCDILKK VLEYQQSNEY
WAALNASKCP QCGRLIQRTE GCFHLKCLCG QHFCFKCSGP WAKDHEKSFY TCPFTNTNKN
PSKHAVQLKN ELQNVNTNIQ NILSSIKNLK LKIKKVQLDS IIEYSEKIIN LLKTSKSFLY
YKFYLLENND VSIYEQTFQQ FQELMDFFIQ ILENKIQEIE DNESLKGQFI LEFIHFDDSE
KKILQNLKIQ KKIIKKYIVE TLIM
//
