ID   A0A8S1KY63_PARPR        Unreviewed;      1240 AA.
AC   A0A8S1KY63;
DT   12-OCT-2022, integrated into UniProtKB/TrEMBL.
DT   12-OCT-2022, sequence version 1.
DT   02-APR-2025, entry version 14.
DE   RecName: Full=RING-type domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=PPRIM_AZ9-3.1.T0270198 {ECO:0000313|EMBL:CAD8058403.1};
OS   Paramecium primaurelia.
OC   Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC   Oligohymenophorea; Peniculida; Parameciidae; Paramecium.
OX   NCBI_TaxID=5886 {ECO:0000313|EMBL:CAD8058403.1, ECO:0000313|Proteomes:UP000688137};
RN   [1] {ECO:0000313|EMBL:CAD8058403.1}
RP   NUCLEOTIDE SEQUENCE.
RG   Genoscope - CEA;
RA   William W.;
RL   Submitted (JAN-2021) to the EMBL/GenBank/DDBJ databases.
CC   -!- PATHWAY: Protein modification; protein ubiquitination.
CC       {ECO:0000256|ARBA:ARBA00004906}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CAD8058403.1}.
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DR   EMBL; CAJJDM010000026; CAD8058403.1; -; Genomic_DNA.
DR   OMA; KEDIRFC; -.
DR   Proteomes; UP000688137; Unassembled WGS sequence.
DR   GO; GO:0000151; C:ubiquitin ligase complex; IEA:TreeGrafter.
DR   GO; GO:0043130; F:ubiquitin binding; IEA:TreeGrafter.
DR   GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:TreeGrafter.
DR   GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IEA:TreeGrafter.
DR   GO; GO:0097039; P:protein linear polyubiquitination; IEA:TreeGrafter.
DR   CDD; cd20335; BRcat_RBR; 1.
DR   CDD; cd22585; Rcat_RBR_DEAH12-like; 1.
DR   InterPro; IPR002867; IBR_dom.
DR   InterPro; IPR051628; LUBAC_E3_Ligases.
DR   InterPro; IPR044066; TRIAD_supradom.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR017907; Znf_RING_CS.
DR   PANTHER; PTHR22770:SF13; RING-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR22770; UBIQUITIN CONJUGATING ENZYME 7 INTERACTING PROTEIN-RELATED; 1.
DR   Pfam; PF01485; IBR; 1.
DR   SMART; SM00647; IBR; 1.
DR   SMART; SM00184; RING; 1.
DR   PROSITE; PS51873; TRIAD; 1.
DR   PROSITE; PS00518; ZF_RING_1; 1.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000688137};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00175}.
FT   DOMAIN          1029..1232
FT                   /note="RING-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51873"
FT   DOMAIN          1033..1080
FT                   /note="RING-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50089"
SQ   SEQUENCE   1240 AA;  145685 MW;  8A68373425895453 CRC64;
     MYLTRQGQVR IKYASQQKNF HDNVNRYNFE RKTIVIDYSN IDIEKQIPEQ FTKQNYKYCS
     QISNVDYKYD ILIINPALID QIKTNGFQVV EIQTPVLPIE QRRFLSDYNT QEQKLQLIHK
     TIMQQINEER DILIYCMDAN EIEYLRVLFE QSQIRVIVKI DNEFNQLFNR VMHQPNYSNT
     VFLLMEPQQL ESYNITLIIH TNQREIIKRR DDNTIEYSYQ NLSQVDLQVR EISKSNSEGI
     MIYYAFSEQQ YLQLTMQAQK SSNIDLESDI FEKLLCNLSK QEDCKYLQKF GIMIAALFTS
     GQLLQIFDKQ CLQKQLSIKT SSYWSKQGDY HSWYNIIMQI IVLLNSCEDE KISSIIKKFC
     NDNKINLIKA LLIIAKLKYF SSLYEIDDLD VLDGLQQLNL KKQSSSIDGF QTDNEYQLEQ
     LFPISRDYKM HKYSLQKIFK IINLPQYILG IKENQVLYSA VAENKFRKIS VQEHIVQNIC
     TAVMNLLWND EESEISKLEH KYKCIIEPFN INNLVIYSDN SKQVEDELVS IISKFKQQLS
     QQVKEYEYQN SNIRFIISNG GVIDKCYYSN NSILEISQLS LETKESEIRS LIEPYSLINT
     ITLIPYKISQ TAQIDLRDKD ATLEIINDLD ETEFQGCTIK VSSTYIKKEQ NKKFHPYIIK
     LSWFIYHCKG NAEITFNNEM AAQEFYNQYN DTILDGKKMI MQVNNDIVNI SNLTQYITEL
     DLFRLSTKIK SINISKSVLY EPKFDIFQKV ESLLFDENRK HHIGFKHQQL YRIRNQRKDY
     KRVLKLGVPS INFVNSALTN FNNLLIQLGL QQVKLYCEAQ YKHQYKVKQD FIKFVRNNIK
     SIQQKFNNLF RIEQVDNSGS EIELHLVSDN YMVFSKVRDT IQNIIDGYII NFGELNTILF
     SDVGQQFIQE LEIQKSVIIS LDQFKKIIKV YCLDEQFQEL QDIIKSFLES NSTITVRLTP
     QKLKKLLGDD YQGLLFLQQK FKLTDVVPIK KNNQLKLSGQ AKNLEEAIQY LEAFLESKDE
     NIENQSINQD NTCCYCLNQM KQPYILTNCN HKFCNECLNY DFSNSIKDIN SLPIKCSLCQ
     NLILLEDIQN ILGLAKYEKL VELSINKYVN DMRGVLIFCF NPGCSNILRV KGDTIYCENC
     KVTYCLKCKV QMHYGMTCWE YQTGDQKIME ELMKKEDIRF CPVCRSLAQK ISGCMSVACS
     SCKKYICWKN LPNSSKPCMK VFNNSTECHQ HLTNVHGGYY
//