ID A0A8S1T771_PAROT Unreviewed; 1903 AA.
AC A0A8S1T771;
DT 12-OCT-2022, integrated into UniProtKB/TrEMBL.
DT 12-OCT-2022, sequence version 1.
DT 02-APR-2025, entry version 13.
DE RecName: Full=ATP-dependent RNA helicase {ECO:0008006|Google:ProtNLM};
GN ORFNames=POCTA_138.1.T0180335 {ECO:0000313|EMBL:CAD8146502.1};
OS Paramecium octaurelia.
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC Oligohymenophorea; Peniculida; Parameciidae; Paramecium.
OX NCBI_TaxID=43137 {ECO:0000313|EMBL:CAD8146502.1, ECO:0000313|Proteomes:UP000683925};
RN [1] {ECO:0000313|EMBL:CAD8146502.1}
RP NUCLEOTIDE SEQUENCE.
RG Genoscope - CEA;
RA William W.;
RL Submitted (JAN-2021) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the DEAD box helicase family. DEAH subfamily.
CC PRP16 sub-subfamily. {ECO:0000256|ARBA:ARBA00038040}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CAD8146502.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CAJJDP010000018; CAD8146502.1; -; Genomic_DNA.
DR OMA; VEICNKC; -.
DR OrthoDB; 299620at2759; -.
DR Proteomes; UP000683925; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:TreeGrafter.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR CDD; cd20335; BRcat_RBR; 1.
DR CDD; cd17917; DEXHc_RHA-like; 1.
DR CDD; cd22585; Rcat_RBR_DEAH12-like; 1.
DR CDD; cd18791; SF2_C_RHA; 1.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C-like.
DR InterPro; IPR002867; IBR_dom.
DR InterPro; IPR044066; TRIAD_supradom.
DR InterPro; IPR027370; Znf-RING_euk.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF91; PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE PRP16; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF01485; IBR; 1.
DR Pfam; PF22191; IBR_1; 1.
DR Pfam; PF13445; zf-RING_UBOX; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00647; IBR; 2.
DR SMART; SM00184; RING; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS51873; TRIAD; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022806};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000683925};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 489..650
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 667..846
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 1694..1903
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS51873"
FT DOMAIN 1698..1738
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
SQ SEQUENCE 1903 AA; 225566 MW; 337C6FCF662F99DD CRC64;
MNSNAIVNQN TLRDVQMVYQ KAIRMISCLK EKHKLITRIR LVDSDKAIFQ ELAQGMGQLI
ELLRKGCDVH LIFKQNLPYF EVQLDLEPFI VEPGKMKEYL LRKQLRELGL KNIKFESKEC
REHNIADDFI NQEDEFKRDE CAELLKERFD TFKVQDEQAI IEILKKYLKK NLIETYNREL
IDIRFYINQD FEIVIEYKIN DNQLNLQKKI KRRKWSEIKD AISHFYTYQY LQEITLSMIE
QMFYIDEIEF TELSRCVQQI VQDFKSSYNQ NLKYPISIYK SSYWDILGIL PRSLNTHNRF
GQCKIMIIQN QSRLFFLNHQ KIIENEQIKN DITLFQTYTQ LIADSKQRLE MIKKNVTSGN
TQNLIKQKKE LIEKLQILPE LEQEIYDQEI LEKQKSDQQN YYNEEDFILQ EEIYDQMKAI
TDKIEQTKQI YAEYHRVLNK VKNDVINFQG LKTIQENKIY LKNLYKRVLQ EKQRVIQKLP
IYFKKRELID NIQQSQAILL IGATGSGKST QLVQYIYEEI ELKGKIMCVE PRMIAARSLA
KRVAEEMHTK LGGRVAYLNE YDQLDDENKI IFTQDRIILN ILQKDPLLND YEIVIIDEAH
ERNMNTDILL GLLKDIMNKR KDLKIIIMSA TMDEQLFSRY FQCQAFKVEG KLFDVKIKYQ
NSYSDRYIEQ IYSLIQDKII SKVMNETYTQ RHVLVFLAGV DEIHRLLYLF QDYFDMDEFL
FLGLHGQMTQ DEQFNVFQET RKIKIIFSTR VAETALTIND VSVVIDIGVD RFSEYDQKRG
MQITKINWIS QAQANQRAGR AGRTRQGKCY RLYSEMEYLT QMQEHKTPEI QRCCLDLVVL
RIKSFNKDPF EFEFIQSPNH QAMRDSQQYL IDIKALDEQG NITVLGKFMS QIQTEPRMSR
ILIEAYYKNV FREALSIICV MLNNQSLYLK NTDISNKIEC LHEMGDFFTY SRVYWDFKSL
IDSNYSNAQI KQRCLEKGYH YKTLKNCEKA FDEMEKTFSY FDLQLCDNQE LKNKILWNSD
ATRDECVMTC FLTAFYPDLC VYNGNPYIGY TFLKSKRNVR IYGSSTLSLL NHFPKYIICS
DLYSSDYFDF CRVAQEVKIE KLKEILKPSQ IEEIENFVPD KYQYQQLRNV SSSLLNHLMH
TFNQYSYDEQ EKRFSYYCNK DLDNGIFEMW SLKPIDLEFY QKDYYEKLKS YLYFRLYGQG
MLVYFKHGAQ IHDTQQCTQS ELAIVQFFSS PFNIGEIQQI LNEQHLYYNN LFQINANKFG
YCGQIFTNSQ ESANQITYVL NEKAEQRLKL QNEQQYYERQ QLFTIKPREL RNRVIRSSVE
LIFYGCLNKG FGFVQFNNSE EAEDFLIKTI SIVKFKGWQQ DLKICQDKNT KIRISNVPYN
ANEYELLKYL KELAQQKGCS KPHSLHLISN EQVETKDWNQ EINKVFEKYT GEKPLHLDIR
ADKNNYRILV RVMATTNPIK LEEMRKQINF AENVIGCSSV TMKIEYKIIK IISKSILLLN
EEKINNIKQQ LQAKYSEDLL RIFSSGENMI IIGKNPNLVR QASLMLHGVL NGYQLKVSLR
KQVFKQILRN RQFFEDLLSL QDVHGFKFNT GLLQFGKIKV YLNQDSLIEI QNAINSMINQ
QVSSNLIVSI RNYSFKSLLT IKDNIMFMLQ EKYNVSIDFI LQKKQIIIYG NNEQAQKCKD
HLLKSLSKSP EVQQQNICEI CYGELTEKYV LALCNHIFCK SCLYESIKVQ NNSPYKCPQQ
SCDNSISLYD LQQILCEIEF SKLLDQSFKR YKDQHAHEYV GCITPDCEEF FKKLPEDKEQ
FYYCQSCLQS FCLQCKRNAH PKISCEEAKK LFIDGKDLDE SELLKMNIKR CPKCQMGVQK
NEGCRHLHCT NCGNHFCWVC LHQANLSQDI YAHLNHYHGG AYE
//
