ID A0A8S9B626_9HELO Unreviewed; 563 AA.
AC A0A8S9B626;
DT 12-OCT-2022, integrated into UniProtKB/TrEMBL.
DT 12-OCT-2022, sequence version 1.
DT 02-APR-2025, entry version 9.
DE RecName: Full=RBR-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012251};
DE EC=2.3.2.31 {ECO:0000256|ARBA:ARBA00012251};
GN ORFNames=EG329_002838 {ECO:0000313|EMBL:KAE8442805.1};
OS Mollisiaceae sp. DMI_Dod_QoI.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Helotiales; Mollisiaceae.
OX NCBI_TaxID=2728926 {ECO:0000313|EMBL:KAE8442805.1, ECO:0000313|Proteomes:UP000423986};
RN [1] {ECO:0000313|EMBL:KAE8442805.1, ECO:0000313|Proteomes:UP000423986}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DMI_Dod_QoI {ECO:0000313|EMBL:KAE8442805.1,
RC ECO:0000313|Proteomes:UP000423986};
RA Lichtner F.J.;
RT "Venturia inaequalis Genome Resource.";
RL Submitted (JUL-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.;
CC EC=2.3.2.31; Evidence={ECO:0000256|ARBA:ARBA00001798};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAE8442805.1}.
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DR EMBL; VXCB01000141; KAE8442805.1; -; Genomic_DNA.
DR OrthoDB; 1431934at2759; -.
DR Proteomes; UP000423986; Unassembled WGS sequence.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016567; P:protein ubiquitination; IEA:InterPro.
DR CDD; cd20335; BRcat_RBR; 1.
DR Gene3D; 1.20.120.1750; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR031127; E3_UB_ligase_RBR.
DR InterPro; IPR002867; IBR_dom.
DR InterPro; IPR044066; TRIAD_supradom.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR11685; RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING; 1.
DR Pfam; PF01485; IBR; 1.
DR SMART; SM00647; IBR; 1.
DR SUPFAM; SSF57850; RING/U-box; 3.
DR PROSITE; PS51873; TRIAD; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000423986};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 304..563
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS51873"
FT DOMAIN 308..362
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 1..91
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 201..228
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 462..488
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 502..550
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..15
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 59..68
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 470..488
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 502..529
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 530..542
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 563 AA; 63873 MW; B002EF86519FA61A CRC64;
MSKMKRLLRS FSKRNLRNEE ENEVDSSPRT ENFQRRPVWS IDEEEPWSFN RLNDGEAAEQ
SSSRNAPQVS GFEQYRKDMN IPPSRTPQKK PDTRFIHELE AESNTWAQGH SSSSSEANDP
LQAIYGTADI QFFGSQYGLG AAKVESPDEI ASAYHDQMVE QVAALNFYEE MMRNAAPDIQ
RAATGKAETL WGNTLKSAAT AEPDLASTSE YPASRDIQDD QNSQKPEITK TGMFGVADAE
EFWRTVMSIA TTPDTPAVPA AESSKAAALN SVPQELPTEV HSVAIPSFFP ATATIPTDTS
AERLPTNCII CIEDFTPDFS APPWITHACT HPPSVCLPCL AKCIKNDLDN KIWNQIKCPE
CDVTLVYEDI KRLADPETFV RYEELSFRSA VSSDSDFIWC PSPSCGFGQL HATGQKHPIV
RCLKCGFRSC FKHGVAWHER LTCDEYDEML QNPIGFKSAL EREEEERIAE EERQRQRHEA
ELARARAQQE AEAERRRWEE MRREEAEQRK REEAERQRQR EEVLRKQMEE QASMSTVQNT
TKRCPGCSWP IEKNRGCAHM TLS
//
