ID A0A8T0BR95_SILME Unreviewed; 1254 AA.
AC A0A8T0BR95;
DT 12-OCT-2022, integrated into UniProtKB/TrEMBL.
DT 12-OCT-2022, sequence version 1.
DT 28-JAN-2026, entry version 13.
DE RecName: Full=Thrombospondin-like N-terminal domain-containing protein {ECO:0000259|SMART:SM00210};
GN ORFNames=HF521_017960 {ECO:0000313|EMBL:KAF7708903.1};
OS Silurus meridionalis (Southern catfish) (Silurus soldatovi meridionalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC Siluridae; Silurus.
OX NCBI_TaxID=175797 {ECO:0000313|EMBL:KAF7708903.1, ECO:0000313|Proteomes:UP000606274};
RN [1] {ECO:0000313|EMBL:KAF7708903.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=SWU-2019-XX {ECO:0000313|EMBL:KAF7708903.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:KAF7708903.1};
RA Zhang Y., Wang D., Peng Z.;
RT "Chromosome-level assembly of Southern catfish (Silurus meridionalis)
RT provides insights into visual adaptation to the nocturnal and benthic
RT lifestyles.";
RL Submitted (AUG-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAF7708903.1}.
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DR EMBL; JABFDY010000004; KAF7708903.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A8T0BR95; -.
DR Proteomes; UP000606274; Unassembled WGS sequence.
DR GO; GO:0005581; C:collagen trimer; IEA:UniProtKB-KW.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR FunFam; 2.60.120.200:FF:000039; Collagen XV alpha 1 chain; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR Gene3D; 3.40.1620.70; -; 1.
DR Gene3D; 3.10.100.10; Mannose-Binding Protein A, subunit A; 1.
DR InterPro; IPR016186; C-type_lectin-like/link_sf.
DR InterPro; IPR008160; Collagen.
DR InterPro; IPR050938; Collagen_Structural_Proteins.
DR InterPro; IPR010515; Collagenase_NC10/endostatin.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR016187; CTDL_fold.
DR InterPro; IPR048287; TSPN-like_N.
DR InterPro; IPR045463; XV/XVIII_trimerization_dom.
DR PANTHER; PTHR37456:SF6; COLLAGEN ALPHA-1(XXIII) CHAIN-LIKE ISOFORM X2; 1.
DR PANTHER; PTHR37456; SI:CH211-266K2.1; 1.
DR Pfam; PF01391; Collagen; 4.
DR Pfam; PF20010; Collagen_trimer; 1.
DR Pfam; PF06482; Endostatin; 1.
DR SMART; SM00210; TSPN; 1.
DR SUPFAM; SSF56436; C-type lectin-like; 2.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
PE 4: Predicted;
KW Collagen {ECO:0000256|ARBA:ARBA00023119};
KW Reference proteome {ECO:0000313|Proteomes:UP000606274};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..1254
FT /note="Thrombospondin-like N-terminal domain-containing
FT protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5035790157"
FT DOMAIN 36..224
FT /note="Thrombospondin-like N-terminal"
FT /evidence="ECO:0000259|SMART:SM00210"
FT REGION 221..687
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 705..984
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 255..267
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 305..323
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 341..352
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 372..381
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 467..496
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 565..575
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 602..616
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 639..651
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 652..669
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 779..795
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 810..819
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 840..858
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 886..901
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 924..933
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 966..980
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1254 AA; 128991 MW; 48E2E36B53E9C9BE CRC64;
MAIRVSPWCW LYLSALGLLH PATGFQLQDE RSSSNQLDLT ELIGVPLPPS VSFITGFEGF
PAYSFGPDAN VGRLTRSFIP DPFFHDFAII VTAKPTTRHG GVLFAITDAL QKIVHLGVAL
APVEDGSQRV VLYYTEPGTA RTQEAASFKM GDLTGHWARF TLAVQGDEVK LYMDCEEHHR
VAFHRSQKGL TFEPSSGIFV GNAGGTRLQR FVGSIQQLVL TPDPRAPDEQ CEEDDPYASG
YGSGDNEYDD TETPDEVKKV HEEREYPPDE DQTLPVRAPP TEASSEGPFD DEDLEEGSSG
QDVVPIDREP SRTEKAVYNK GDDYPLTMPV HKGEKGDRGP AGPPGPPGPP GTPSSSGPKG
DISSWVGQPG ARGPPGPPGP TGAPGKDGLP GSRGEDGKSG ETGVPGFPGI PGDPGIKGEK
GDAGIGLPGI PGPPGPPGRS GAPRYVDAID GSGFEDFDSD TEVIRGPPGP PGPPGQPGPP
GPPQGLLPGP MGPPGAPGKD GLMGVPGIPG ISGKYGEPGN DGQKGDKGDT GLPGHAGQKG
DTGQPGLPGS PGTAGPEGPK GEPGPAGPPG PPGPPSRFNF DLLDSEGSGV GGGSGFGQNI
PRGPPGIPGL PGPPGPKGKD GVNGLPGTSE KGEPGPAGPE GKPGQSGLPG KNGEKGEKGE
MGQKGERGLD GVSIPGPPGP PGPVINLQDL MLNDTEGLYN FTGIFDPQGP LGPRGPKGDR
GIPGVPGHPG LKGEKGEPGL TIGPDGSLLS GPQGPKGLKG DHGVHGLPGA MGPVGPSGPK
GEFGFPGRPG RPGLNGRKGE KGDSNGLQGP PGPPGPPGRP GIFNCPKGTV FPIPPRPHCK
TSTNGNSTSE GASCSTSGAK GEKGERGLPG PPGTTITMLG AGSVGDKGDY GLRGEKGEKG
EAGMPGAPGQ PGTSGVVGPK GDSIIGPPGR PGLQGPPGSP GIGRPGATGL RGPPGPPGYS
SAAAIPGPPG PQGPPGPPGP AGGGFGSIKK YPTLYAMKSY VVEVGTLSMV TDTGKLYLKV
QGGWKEILLG GLIEVNSPAV LSQDDAQPLI LTPQLSNTHK THTGSALRLV ALNTPLTGDL
GSIHSVNKQC RLQAQAMGIR DDYKAFLSHH LQDLIDIVQL PYRTSLPIVN LRGEVLFKNW
ESIFSHHALP AGIPLYSFDG RDVMSDPFWP QKAIWHGSSE RGRRLDDKNC ESWRAGDMAI
TGQASFLYSG LLNQQTRSCS NQFIVLCIEI NPDHNTVEEL KRAQYRHRRW HHRY
//
