ID A0A8T0FLX4_ARGBR Unreviewed; 653 AA.
AC A0A8T0FLX4;
DT 12-OCT-2022, integrated into UniProtKB/TrEMBL.
DT 12-OCT-2022, sequence version 1.
DT 28-JAN-2026, entry version 13.
DE RecName: Full=Forkhead box protein L2 {ECO:0000256|ARBA:ARBA00034872};
GN ORFNames=HNY73_006263 {ECO:0000313|EMBL:KAF8791385.1};
OS Argiope bruennichi (Wasp spider) (Aranea bruennichi).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Araneae;
OC Araneomorphae; Entelegynae; Araneoidea; Araneidae; Argiope.
OX NCBI_TaxID=94029 {ECO:0000313|EMBL:KAF8791385.1, ECO:0000313|Proteomes:UP000807504};
RN [1] {ECO:0000313|EMBL:KAF8791385.1}
RP NUCLEOTIDE SEQUENCE.
RA Sheffer M.M., Hoppe A., Krehenwinkel H., Uhl G., Kuss A.W., Jensen L.,
RA Jensen C., Gillespie R.G., Hoff K.J., Prost S.;
RT "Chromosome-level reference genome of the European wasp spider Argiope
RT bruennichi: a resource for studies on range expansion and evolutionary
RT adaptation.";
RL bioRxiv 0:0-0(2020).
RN [2] {ECO:0000313|EMBL:KAF8791385.1}
RP NUCLEOTIDE SEQUENCE.
RA Sheffer M.;
RL Submitted (JUN-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00089}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAF8791385.1}.
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DR EMBL; JABXBU010000011; KAF8791385.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A8T0FLX4; -.
DR Proteomes; UP000807504; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:TreeGrafter.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:TreeGrafter.
DR GO; GO:0009653; P:anatomical structure morphogenesis; IEA:TreeGrafter.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR FunFam; 1.10.10.10:FF:000135; forkhead box protein G1; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR001766; Fork_head_dom.
DR InterPro; IPR050211; FOX_domain-containing.
DR InterPro; IPR018122; TF_fork_head_CS_1.
DR InterPro; IPR030456; TF_fork_head_CS_2.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11829; FORKHEAD BOX PROTEIN; 1.
DR PANTHER; PTHR11829:SF411; FORKHEAD BOX PROTEIN L2; 1.
DR Pfam; PF00250; Forkhead; 1.
DR PRINTS; PR00053; FORKHEAD.
DR SMART; SM00339; FH; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00657; FORK_HEAD_1; 1.
DR PROSITE; PS00658; FORK_HEAD_2; 1.
DR PROSITE; PS50039; FORK_HEAD_3; 1.
PE 4: Predicted;
KW Differentiation {ECO:0000256|ARBA:ARBA00022782};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00089}; Isopeptide bond {ECO:0000256|ARBA:ARBA00022499};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00089}; Reference proteome {ECO:0000313|Proteomes:UP000807504};
KW Ubl conjugation {ECO:0000256|ARBA:ARBA00022843}.
FT DOMAIN 408..501
FT /note="Fork-head"
FT /evidence="ECO:0000259|PROSITE:PS50039"
FT DNA_BIND 408..501
FT /note="Fork-head"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00089"
FT REGION 181..213
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 263..336
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 204..213
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 301..313
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 317..336
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 653 AA; 72342 MW; 7DB5AD34D4B2D5DE CRC64;
MSFEDAFVEH SSRPWPSLTY GKIRLWILAR LHQMSTKQHY ELNLIECVMK LNIHKNEMEQ
CRLRCTALGA LIRRISNIII NSLKASPSPL DMTSVSYTSC AATTGFSDTG IAPRSAPYPV
ALYPCSGRER IGEESCQPKS STSPVLSPSH LYTSYSEPNG AGVFKTSSPL HFSSAYPMYT
SRSETTDTGL SRDCARSYTP YPRTRSNNIS RHLNSGSYVT SYSPPHCDNR STSSIATTNL
LHSSSTPLLS NCIDDPESHT LHHTTNDCND EASHSNNETG MTMNVDPVDP TTANSSTSEC
ENERKGIKRR LSESSEENTS IKIKNSPSIS DLRQPSLCSD NKAMSLNTAD PFNVDTKPTN
HSGSIIVQPF GGNSKSMKLG AANVSNSSKV HINTSSSGGM SGSVKQERPP FSYVAMIRQA
ILESPSKRLT LQEIYSYVLG TFPYYKSKDG WKNSIRHNLS LNKCFIRVPR EGGGEKKGSF
WTFDPAFNDM FEGNNYRRRK RMKRPSREGV HVQSSGASFT PTFTPTFTRP YAHTYLNPSD
FLTSDYRSVA STERNWPLAH MQGSSQLRHS GRSSLASYPS CQRMQAQTLH VGYMQSSQMD
PSISTSTQSS IPLPAAYPAH SYVPPPAAFP GHYPTHCLRE SACSTPQSRY HPY
//
