ID A0A8T1QBD6_CARIL Unreviewed; 590 AA.
AC A0A8T1QBD6;
DT 12-OCT-2022, integrated into UniProtKB/TrEMBL.
DT 12-OCT-2022, sequence version 1.
DT 18-JUN-2025, entry version 13.
DE RecName: Full=RBR-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012251};
DE EC=2.3.2.31 {ECO:0000256|ARBA:ARBA00012251};
GN ORFNames=CIPAW_06G138200 {ECO:0000313|EMBL:KAG6651806.1},
GN I3842_06G139200 {ECO:0000313|EMBL:KAG6709584.1};
OS Carya illinoinensis (Pecan).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fagales; Juglandaceae; Carya.
OX NCBI_TaxID=32201 {ECO:0000313|EMBL:KAG6651806.1, ECO:0000313|Proteomes:UP000811609};
RN [1] {ECO:0000313|EMBL:KAG6651806.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAG6651806.1};
RA Platts A., Shu S., Wright S., Barry K., Edger P., Pires J.C., Schmutz J.;
RT "WGS assembly of Carya illinoinensis cv. Pawnee.";
RL Submitted (DEC-2020) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KAG6709584.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAG6709584.1};
RA Lovell J.T., Bentley N., Bhattarai G., Jenkins J.W., Sreedasyam A.,
RA Alarcon Y., Bock C., Boston L., Carlson J., Cervantes K., Clermont K.,
RA Krom N., Kubenka K., Mamidi S., Mattison C., Monteros M., Pisani C.,
RA Plott C., Rajasekar S., Rhein H.S., Rohla C., Song M., Hilaire R.S.,
RA Shu S., Wells L., Wang X., Webber J., Heerema R.J., Klein P., Conner P.,
RA Grauke L., Grimwood J., Schmutz J., Randall J.J.;
RL Submitted (JAN-2021) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Might act as an E3 ubiquitin-protein ligase, or as part of E3
CC complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating
CC enzymes and then transfers it to substrates.
CC {ECO:0000256|ARBA:ARBA00003976}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.;
CC EC=2.3.2.31; Evidence={ECO:0000256|ARBA:ARBA00001798};
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- SIMILARITY: Belongs to the RBR family. Ariadne subfamily.
CC {ECO:0000256|ARBA:ARBA00005884}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAG6651806.1}.
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DR EMBL; CM031814; KAG6651806.1; -; Genomic_DNA.
DR EMBL; CM031830; KAG6709584.1; -; Genomic_DNA.
DR OrthoDB; 10009520at2759; -.
DR Proteomes; UP000811246; Chromosome 6.
DR Proteomes; UP000811609; Chromosome 6.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016567; P:protein ubiquitination; IEA:InterPro.
DR CDD; cd20346; BRcat_RBR_ANKIB1; 1.
DR CDD; cd22586; Rcat_RBR_ARI1-like; 1.
DR CDD; cd16773; RING-HC_RBR_TRIAD1; 1.
DR FunFam; 1.20.120.1750:FF:000013; RBR-type E3 ubiquitin transferase; 1.
DR FunFam; 3.30.40.10:FF:000019; RBR-type E3 ubiquitin transferase; 1.
DR Gene3D; 1.20.120.1750; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR045840; Ariadne.
DR InterPro; IPR048962; ARIH1-like_UBL.
DR InterPro; IPR031127; E3_UB_ligase_RBR.
DR InterPro; IPR002867; IBR_dom.
DR InterPro; IPR044066; TRIAD_supradom.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR11685; RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING; 1.
DR Pfam; PF19422; Ariadne; 1.
DR Pfam; PF01485; IBR; 2.
DR Pfam; PF21235; UBA_ARI1; 1.
DR SMART; SM00647; IBR; 2.
DR SUPFAM; SSF57850; RING/U-box; 3.
DR PROSITE; PS51873; TRIAD; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000811609};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 120..334
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS51873"
FT DOMAIN 124..172
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 539..590
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 540..550
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 552..563
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 590 AA; 67621 MW; 0AD5E4D8070FF5D5 CRC64;
MSLLLSMEDC ASDGDNYCSD RDSLDGIENE EPEFQCAPPK GSTTKVITKE SLLAAQREDL
RRVMEMLSLR EHHARTLLIH YRWDVERLVA VLVEKGKACL FAEAGVTVVG HQDLDSSLPS
IVMCDICMEG RPGGETTRVD CGHCFCNNCW TEHFMVKINE GQSRRIRCMA HKCNSICDEA
VVRNLVSKKH PDMAEKFDRF LLESYIEDNK RVKWCPSAPH CGNAIRIEDD EFCEVECSCG
LQFCFSCLSE AHSPCSCIMW QLWVKKCRDE SETVNWITAH TQPCPKCHKP VEKNGGCNLV
SCICGQAFCW LCGGATGRDH NWSSITGHSC GRFKVEGEKK SERAKRDHYR YIHYYNRYRA
HTDSFKQESK LKETIQERVS ITEERDSRLR DFSWVNNGLY RLFRSRRVLS YSYPFAFYMF
GDELFKDEMT KEESEIKQHL FEDQQQQLEA NVEKLSKILE EPFDQYSEDK VMEIRMQVIN
LSVITDTLCH KLYECIENDL LGSLQFGNHN IAPYKSKGIE RASELTACWK SNNRDNYLPS
DHEASAESDR PSGSGCSDES GCSSRKRARK DGVGSGLFDL NMPAEVIDRN
//
