ID A0A8U0A3Y6_9EURY Unreviewed; 309 AA.
AC A0A8U0A3Y6;
DT 12-OCT-2022, integrated into UniProtKB/TrEMBL.
DT 12-OCT-2022, sequence version 1.
DT 28-JAN-2026, entry version 15.
DE RecName: Full=Formimidoylglutamase {ECO:0000256|NCBIfam:TIGR01227};
DE EC=3.5.3.8 {ECO:0000256|NCBIfam:TIGR01227};
GN Name=hutG {ECO:0000313|EMBL:UPM42673.1};
GN ORFNames=MW046_12015 {ECO:0000313|EMBL:UPM42673.1};
OS Halocatena salina.
OC Archaea; Methanobacteriati; Methanobacteriota; Stenosarchaea group;
OC Halobacteria; Halobacteriales; Natronomonadaceae; Halocatena.
OX NCBI_TaxID=2934340 {ECO:0000313|EMBL:UPM42673.1, ECO:0000313|Proteomes:UP000831768};
RN [1] {ECO:0000313|EMBL:UPM42673.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=AD-1 {ECO:0000313|EMBL:UPM42673.1};
RA Cui H.-L.;
RT "Halocatena sp. nov., isolated from a salt lake.";
RL Submitted (APR-2022) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the arginase family. {ECO:0000256|PROSITE-
CC ProRule:PRU00742}.
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DR EMBL; CP096019; UPM42673.1; -; Genomic_DNA.
DR RefSeq; WP_247993344.1; NZ_CP096019.1.
DR AlphaFoldDB; A0A8U0A3Y6; -.
DR GeneID; 71928784; -.
DR KEGG; haad:MW046_12015; -.
DR Proteomes; UP000831768; Chromosome.
DR GO; GO:0008783; F:agmatinase activity; IEA:TreeGrafter.
DR GO; GO:0050415; F:formimidoylglutamase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0019556; P:L-histidine catabolic process to glutamate and formamide; IEA:UniProtKB-UniRule.
DR GO; GO:0033389; P:putrescine biosynthetic process from arginine, via agmatine; IEA:TreeGrafter.
DR CDD; cd09990; Agmatinase-like; 1.
DR Gene3D; 3.40.800.10; Ureohydrolase domain; 1.
DR InterPro; IPR005923; HutG.
DR InterPro; IPR006035; Ureohydrolase.
DR InterPro; IPR023696; Ureohydrolase_dom_sf.
DR NCBIfam; TIGR01227; hutG; 1.
DR PANTHER; PTHR11358; ARGINASE/AGMATINASE; 1.
DR PANTHER; PTHR11358:SF26; GUANIDINO ACID HYDROLASE, MITOCHONDRIAL; 1.
DR Pfam; PF00491; Arginase; 1.
DR PIRSF; PIRSF036979; Arginase; 1.
DR SUPFAM; SSF52768; Arginase/deacetylase; 1.
DR PROSITE; PS51409; ARGINASE_2; 1.
PE 3: Inferred from homology;
KW Histidine metabolism {ECO:0000256|ARBA:ARBA00022808};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:UPM42673.1};
KW Manganese {ECO:0000256|ARBA:ARBA00023211};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000831768}.
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..10
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 309 AA; 32555 MW; C602F97A3980163C CRC64;
MTGTDLTTQF DWHGPSTDPN DEQFGDVTEA TTLTEAATYE AVVLGEPTDR AVIGRQGAQE
GPSHLRSALN GTKTHHLTRG TVGPVGDLGD VRFSESADVP ARQQTVATIT EDVHALDARP
VFLGGDNSLT YPNARPLLAS GSLGIVSFDA HFDCRSGAPS SGTPYRQLFD DGLDAFAVVG
ARHFENTTTY AEYLDGRGTV VTAEEVGQDL RAAARTAIDA VADVEQLYVS LDLDVLDVTA
APGVSAPTPG GLTTRELYRL LGTIANDDRV AGFEVVECAP PLDRGDRTAV AGARAIAHVL
SAWTTEDTT
//
