ID   A0A8U0RPT7_MUSPF        Unreviewed;       775 AA.
AC   A0A8U0RPT7;
DT   12-OCT-2022, integrated into UniProtKB/TrEMBL.
DT   12-OCT-2022, sequence version 1.
DT   28-JAN-2026, entry version 16.
DE   SubName: Full=E3 ubiquitin-protein ligase ZNF598 isoform X2 {ECO:0000313|RefSeq:XP_044928062.1};
GN   Name=ZNF598 {ECO:0000313|RefSeq:XP_044928062.1};
OS   Mustela putorius furo (European domestic ferret) (Mustela furo).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC   Mustelinae; Mustela.
OX   NCBI_TaxID=9669 {ECO:0000313|Proteomes:UP000000715, ECO:0000313|RefSeq:XP_044928062.1};
RN   [1] {ECO:0000313|RefSeq:XP_044928062.1}
RP   IDENTIFICATION.
RC   TISSUE=Brain {ECO:0000313|RefSeq:XP_044928062.1};
RG   RefSeq;
RL   Submitted (AUG-2025) to UniProtKB.
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DR   RefSeq; XP_044928062.1; XM_045072127.1.
DR   AlphaFoldDB; A0A8U0RPT7; -.
DR   GeneID; 101678845; -.
DR   CTD; 90850; -.
DR   Proteomes; UP000000715; Unplaced.
DR   GO; GO:0043022; F:ribosome binding; IEA:TreeGrafter.
DR   GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:TreeGrafter.
DR   GO; GO:0072344; P:rescue of stalled ribosome; IEA:InterPro.
DR   InterPro; IPR057634; PAH_ZNF598/HEL2.
DR   InterPro; IPR056437; Znf-C2H2_ZNF598/HEL2.
DR   InterPro; IPR044288; ZNF598/HEL2.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   InterPro; IPR059042; Znf_C2H2_ZNF598.
DR   PANTHER; PTHR22938:SF0; E3 UBIQUITIN-PROTEIN LIGASE ZNF598; 1.
DR   PANTHER; PTHR22938; ZINC FINGER PROTEIN 598; 1.
DR   Pfam; PF23202; PAH_ZNF598; 1.
DR   Pfam; PF23230; zf-C2H2_13; 1.
DR   Pfam; PF23208; zf_C2H2_ZNF598; 1.
DR   SMART; SM00355; ZnF_C2H2; 4.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000000715}.
FT   DOMAIN          52..73
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS00028"
FT   REGION          135..202
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          215..437
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          449..539
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          703..723
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        178..194
FT                   /note="Low complexity"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        215..226
FT                   /note="Low complexity"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        227..255
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        282..296
FT                   /note="Low complexity"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        312..329
FT                   /note="Low complexity"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        359..370
FT                   /note="Low complexity"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        385..400
FT                   /note="Low complexity"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        402..411
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        521..537
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   775 AA;  84128 MW;  02FDE6E03BFBD42C CRC64;
     MRKQHELFCC KLCLKHLKIF TYERKWYSRK DLARHRMQGD PDDTSHRGHP LCKFCDERYL
     DNDELLKHLR RDHYFCHFCD AEGAQDYYSD YAYLREHFRE KHFLCEEGRC STEQFTHAFR
     TEIDLKAHRT TCHSRSRAEA RQNRQIDLQF SYAPRHSRRN EGVVGGEDYE EVDRYNRQGR
     AGRASGRGAQ QNRRGSWRYK REEEDREVAA AIRASVAVQQ QQQQQQEARR SEDREEGGRA
     KKDEAGVRGL EELRGPRRPP RTQGEGAGLK EASPNGPVSP EGTPATGPAP GAVLPSTLPP
     PTSKLKDEDF PSLCASTSSS SSSCSAVAAP GPVGLGLTYP VPARGRSTFQ EDDFPALVSS
     ASKPSTAPTS LISAWNGSGS KKVAHPTAGA PAASGSSQPA RKAGKGGKGS KKAGPLPSEE
     EEEDGRTGLT AQELRSVPTT VAVSSLLALA STQTLTKVGK KKKVGSEKPG AVSPPPLPPD
     KDGPLGAEQT PTTSAGRAEG PVALIVNGHT EGPAPARSTP KEPPGLPRPL GPLPCPTPQE
     DFPALGVPCP PRMPPPPGFS AVVLLKGTPP PPPPGLVPPI SKPPPGFSGL LPGSHPACVP
     STVTTTKAPR LTAAPQAYLV PENFRERNLQ LIQSIRDFLQ SDEARFGKFK SHSGEFRQGV
     ISAAQYYKSC RDLLGENFQK IFNELLVLLP DTAKQQELLS AHTHFRGRER PPGTKAKKNK
     KSAWQGSARP AGLDCCVCPT CQQVLAHGDV SSHQALHAAQ DHDFPSLQAI ARILT
//