ID A0A8W4FNM4_PIG Unreviewed; 1220 AA.
AC A0A8W4FNM4;
DT 14-DEC-2022, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2022, sequence version 1.
DT 28-JAN-2026, entry version 17.
DE SubName: Full=Collagen type XV alpha 1 chain {ECO:0000313|Ensembl:ENSSSCP00000080514.1};
GN Name=COL15A1 {ECO:0000313|Ensembl:ENSSSCP00000080514.1};
OS Sus scrofa (Pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX NCBI_TaxID=9823 {ECO:0000313|Ensembl:ENSSSCP00000080514.1, ECO:0000313|Proteomes:UP000008227};
RN [1] {ECO:0000313|Ensembl:ENSSSCP00000080514.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Duroc {ECO:0000313|Ensembl:ENSSSCP00000080514.1};
RX PubMed=32543654;
RA Warr A., Affara N., Aken B., Beiki H., Bickhart D.M., Billis K., Chow W.,
RA Eory L., Finlayson H.A., Flicek P., Giron C.G., Griffin D.K., Hall R.,
RA Hannum G., Hourlier T., Howe K., Hume D.A., Izuogu O., Kim K., Koren S.,
RA Liu H., Manchanda N., Martin F.J., Nonneman D.J., O'Connor R.E.,
RA Phillippy A.M., Rohrer G.A., Rosen B.D., Rund L.A., Sargent C.A.,
RA Schook L.B., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R.,
RA Tseng E., Tuggle C.K., Watson M., Smith T.P.L., Archibald A.L.;
RT "An improved pig reference genome sequence to enable pig genetics and
RT genomics research.";
RL Gigascience 9:giaa051-giaa051(2020).
RN [2] {ECO:0000313|Ensembl:ENSSSCP00000080514.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (AUG-2025) to UniProtKB.
RN [3] {ECO:0000313|Ensembl:ENSSSCP00000080514.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2025) to UniProtKB.
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DR AlphaFoldDB; A0A8W4FNM4; -.
DR Ensembl; ENSSSCT00000095865.1; ENSSSCP00000080514.1; ENSSSCG00000005380.5.
DR GeneTree; ENSGT00940000158302; -.
DR Proteomes; UP000008227; Chromosome 1.
DR GO; GO:0005581; C:collagen trimer; IEA:UniProtKB-KW.
DR CDD; cd00247; Endostatin-like; 1.
DR CDD; cd00110; LamG; 1.
DR FunFam; 3.40.1620.70:FF:000002; Collagen alpha 1 (XV) chain; 1.
DR FunFam; 2.60.120.200:FF:000039; Collagen XV alpha 1 chain; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR Gene3D; 3.40.1620.70; -; 1.
DR Gene3D; 3.10.100.10; Mannose-Binding Protein A, subunit A; 1.
DR InterPro; IPR016186; C-type_lectin-like/link_sf.
DR InterPro; IPR008160; Collagen.
DR InterPro; IPR050149; Collagen_superfamily.
DR InterPro; IPR010515; Collagenase_NC10/endostatin.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR016187; CTDL_fold.
DR InterPro; IPR001791; Laminin_G.
DR InterPro; IPR048287; TSPN-like_N.
DR InterPro; IPR045463; XV/XVIII_trimerization_dom.
DR PANTHER; PTHR24023; COLLAGEN ALPHA; 1.
DR PANTHER; PTHR24023:SF912; COLLAGEN ALPHA-1(XV) CHAIN; 1.
DR Pfam; PF01391; Collagen; 3.
DR Pfam; PF20010; Collagen_trimer; 1.
DR Pfam; PF06482; Endostatin; 1.
DR Pfam; PF13385; Laminin_G_3; 1.
DR SMART; SM00282; LamG; 1.
DR SMART; SM00210; TSPN; 1.
DR SUPFAM; SSF56436; C-type lectin-like; 2.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
PE 1: Evidence at protein level;
KW Collagen {ECO:0000256|ARBA:ARBA00023119};
KW Proteomics identification {ECO:0007829|PeptideAtlas:A0A8W4FNM4};
KW Reference proteome {ECO:0000313|Proteomes:UP000008227};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 18..206
FT /note="Thrombospondin-like N-terminal"
FT /evidence="ECO:0000259|SMART:SM00210"
FT DOMAIN 67..205
FT /note="Laminin G"
FT /evidence="ECO:0000259|SMART:SM00282"
FT REGION 201..229
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 245..297
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 354..392
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 476..732
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 770..851
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 899..933
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 509..518
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 544..554
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 580..590
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 655..669
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 704..718
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 811..824
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1220 AA; 125434 MW; CEB0E73007C245F1 CRC64;
MCDAWPLSLP AELASQGHLD LTELIGVPLP SSVSFVTGYG GFPAYSFGPG ANVGRPARTL
IPPTFFRDFA ISVTVKPSSA RGGVLFAITD AFQKVIYLGL RLSAVEDGRQ RVILYYTEPG
SQVSHEAASF PVPVMTHRWN RFAVVVQGEE ASLLVECEEQ GHVSFPRSSQ ALAFEPSAGI
FVGNAGATGL ERFTGSIQQL TVHSDPRTPE ELCEAEESSA SGEASGLQET DGVAEMVEAV
TYTQAPSEPA EVEPINMPPT PSPLSEDAEL SGEPVPEGTQ GTTNLSAFPH SSPEQGSGEI
LNDTLERVHT VDGAPVTDTG SGDGAFLHVI EESPHTEEGL AATAAAVESE VTISTAGEAE
TESVPTEGPT LSMSTKDPGE EVTLGPDDEE GSAVTAAEEA EVLVSSPGEA EAGSVPTGEL
TLSMSTQDPG EGGPVHEESL TTAVTAKAPL STFEEEASRV PTDGLAPLIP TVAPEQVFTS
GPGDDDLAAA ATEEPLISSG AEELSGVPPE GPPLPLPTVA PERGGAPGEE GEGLPGPPPP
TRPAGPTAGA EAEGSSLGWG LDIGSGSGDP VRSEELLRGP PGPPGPPGLP GIPGRPGTDV
FVGPPGSPGE DGPAGEPGPP GRIISLSSSL QGDPGSRGLP GPPGKNGQVG TPGVMGPPGP
PGPPGPPGPG CAMGQGFEDT EGSGSIRLLH EPRISGPVAS VGPKGEKGDQ GPKGERGMDG
ASIVGPPGPR GPPGRIEVLS SSLINITHGF MNLSDIPELV GPPGPEGIPG LPGFPGPRGP
KGDTGVPGFP GLKGEQGEKG EPGAILTGDV PLERLRGKKG EPGEHGAPGP MGPKGPPGHK
GEFGLPGRPG RPGLNGLKGA KGDRGVMMPV SATLGPPWGW GGGDTSAVFP IPVRPHCKTP
VSSVKGEKGS WGLPGSKGEK GDQGAQGPPG PPVDPAYLRH FLNSLKGENG DRGMKGEKGD
TYEGFSVSGP PGLPGSPGLV VSRDPSTSSS LKSCSFPRSP QSFSNMDDML QKAHLVIEGT
FIYLRDSTEF FIRVRDGWKK LQLGELIPLP ADSLPPPALS GNPHQPQLPL TSISSVNYDR
PALHLVALNT PSSGDLRADF QCFQQARAAG LLSTYRAFLS SHLQDLSTIV RKAERYSLPI
VNLKGQVLFN NWDSIFSGHG GQFNTHVPIY SFDGRDVMTD PSWPQKVVWH GSSTHGVRLV
DQYCEAWRTA DVAVMGLAPR
//
