ID   A0A8W8J8D2_MAGGI        Unreviewed;       500 AA.
AC   A0A8W8J8D2;
DT   14-DEC-2022, integrated into UniProtKB/TrEMBL.
DT   14-DEC-2022, sequence version 1.
DT   28-JAN-2026, entry version 13.
DE   RecName: Full=SH3 domain-containing protein {ECO:0000259|PROSITE:PS50002};
OS   Magallana gigas (Pacific oyster) (Crassostrea gigas).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC   Autobranchia; Pteriomorphia; Ostreida; Ostreoidea; Ostreidae; Magallana.
OX   NCBI_TaxID=29159 {ECO:0000313|EnsemblMetazoa:G17159.23:cds, ECO:0000313|Proteomes:UP000005408};
RN   [1] {ECO:0000313|EnsemblMetazoa:G17159.23:cds}
RP   IDENTIFICATION.
RC   STRAIN=05x7-T-G4-1.051#20 {ECO:0000313|EnsemblMetazoa:G17159.23:cds};
RG   EnsemblMetazoa;
RL   Submitted (AUG-2022) to UniProtKB.
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DR   AlphaFoldDB; A0A8W8J8D2; -.
DR   EnsemblMetazoa; G17159.23; G17159.23:cds; G17159.
DR   EnsemblMetazoa; G17159.7; G17159.7:cds; G17159.
DR   Proteomes; UP000005408; Unassembled WGS sequence.
DR   GO; GO:0005884; C:actin filament; IEA:TreeGrafter.
DR   GO; GO:0030864; C:cortical actin cytoskeleton; IEA:TreeGrafter.
DR   GO; GO:0005886; C:plasma membrane; IEA:TreeGrafter.
DR   GO; GO:0030427; C:site of polarized growth; IEA:TreeGrafter.
DR   GO; GO:0051015; F:actin filament binding; IEA:TreeGrafter.
DR   GO; GO:0016477; P:cell migration; IEA:TreeGrafter.
DR   GO; GO:0030833; P:regulation of actin filament polymerization; IEA:TreeGrafter.
DR   CDD; cd11959; SH3_Cortactin; 1.
DR   FunFam; 2.30.30.40:FF:000398; Hematopoietic cell-specific Lyn substrate 1; 1.
DR   Gene3D; 2.30.30.40; SH3 Domains; 1.
DR   InterPro; IPR035716; Cortactin_SH3.
DR   InterPro; IPR003134; Hs1_Cortactin.
DR   InterPro; IPR036028; SH3-like_dom_sf.
DR   InterPro; IPR001452; SH3_domain.
DR   PANTHER; PTHR10829; CORTACTIN AND DREBRIN; 1.
DR   PANTHER; PTHR10829:SF23; CORTACTIN, ISOFORM A; 1.
DR   Pfam; PF02218; HS1_rep; 5.
DR   Pfam; PF00018; SH3_1; 1.
DR   PRINTS; PR00452; SH3DOMAIN.
DR   SMART; SM00326; SH3; 1.
DR   SUPFAM; SSF50044; SH3-domain; 1.
DR   PROSITE; PS51090; CORTACTIN; 6.
DR   PROSITE; PS50002; SH3; 1.
PE   4: Predicted;
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005408};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW   ProRule:PRU00192}.
FT   DOMAIN          442..500
FT                   /note="SH3"
FT                   /evidence="ECO:0000259|PROSITE:PS50002"
FT   REGION          1..27
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          66..94
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          150..444
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        66..84
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        170..198
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        210..235
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        291..310
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        320..374
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        382..396
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        413..423
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   500 AA;  56103 MW;  AEF7B7BF8EF8C6A4 CRC64;
     QSSIMWKAAA GHSVKTGKPP VNDDDDDWET EADFVNDVSE QEQRWGAKTI EGSGHKGSLN
     LDQLRQEVST DDKSVKQKQM EEGPKASYGY GGKFGVQKDR MDKSAVGSNY VADVEKHSSQ
     TDAAKGFGGK YGVQKDRQDK AAVGFDYAGK TEKHQSQTDY SKGFGGKYGV QRDRQDKNAV
     GWEHHEQVEK HESQKDYSKG FGGKYGVQTD RVDKSALGYE HHEQVDKHES QKDYSRGFGG
     KYGVQTDRQD KSALGYDSQE KVALHPSQTD MSKGFGGKFG VDAENKDKSA GSYNDMQGVS
     SSYTRTQADA SSEGARNIKA RFENLAKSGE EEAKKKAEEE RKRRQAREER EKEEQRRQQE
     ERLNREKLEE EERAASQPEP QPEPEPEPEP EQEDYGDVSY QPEPVHRQVP EEPPAEEPED
     AYEDTTPQDA YEDITPEPAK SSGGLTAVAI YDYQAADDDE ITFDPDDIIT DIEQVDEGWW
     RGSCRGKNGL FPANYVEIQQ
//