ID A0A8X6FBM5_TRICU Unreviewed; 387 AA.
AC A0A8X6FBM5;
DT 14-DEC-2022, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2022, sequence version 1.
DT 28-JAN-2026, entry version 12.
DE SubName: Full=Forkhead box protein D3-A {ECO:0000313|EMBL:GFQ75056.1};
GN Name=foxd3-a {ECO:0000313|EMBL:GFQ75056.1};
GN ORFNames=TNCT_337171 {ECO:0000313|EMBL:GFQ75056.1};
OS Trichonephila clavata (Joro spider) (Nephila clavata).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Araneae;
OC Araneomorphae; Entelegynae; Araneoidea; Nephilidae; Trichonephila.
OX NCBI_TaxID=2740835 {ECO:0000313|EMBL:GFQ75056.1, ECO:0000313|Proteomes:UP000887116};
RN [1] {ECO:0000313|EMBL:GFQ75056.1}
RP NUCLEOTIDE SEQUENCE.
RA Kono N., Nakamura H., Mori M., Yoshida Y., Ohtoshi R., Malay A.D.,
RA Moran D.A.P., Tomita M., Numata K., Arakawa K.;
RT "Multicomponent nature underlies the extraordinary mechanical properties of
RT spider dragline silk.";
RL Submitted (JUL-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00089}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GFQ75056.1}.
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DR EMBL; BMAO01001661; GFQ75056.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A8X6FBM5; -.
DR OrthoDB; 5402974at2759; -.
DR Proteomes; UP000887116; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:TreeGrafter.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:TreeGrafter.
DR GO; GO:0009653; P:anatomical structure morphogenesis; IEA:TreeGrafter.
DR GO; GO:0030154; P:cell differentiation; IEA:TreeGrafter.
DR FunFam; 1.10.10.10:FF:000598; forkhead box protein I1 isoform X2; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR001766; Fork_head_dom.
DR InterPro; IPR050211; FOX_domain-containing.
DR InterPro; IPR018122; TF_fork_head_CS_1.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11829:SF402; FORK HEAD DOMAIN-CONTAINING PROTEIN FD3-RELATED; 1.
DR PANTHER; PTHR11829; FORKHEAD BOX PROTEIN; 1.
DR Pfam; PF00250; Forkhead; 1.
DR PRINTS; PR00053; FORKHEAD.
DR SMART; SM00339; FH; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00657; FORK_HEAD_1; 1.
DR PROSITE; PS50039; FORK_HEAD_3; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00089};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00089}; Reference proteome {ECO:0000313|Proteomes:UP000887116}.
FT DOMAIN 113..207
FT /note="Fork-head"
FT /evidence="ECO:0000259|PROSITE:PS50039"
FT DNA_BIND 113..207
FT /note="Fork-head"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00089"
FT REGION 66..108
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 387 AA; 42497 MW; A19BD07DB9D9E127 CRC64;
MASEPGPRSQ AISLTNGNLI MDSVQHGALV PRPAYIPSQD LMCSPMMTLP PHDSKLDALV
SVDSDSDVQD TDFDGGGVAE ADTTDPSIEP SFKRQDNNTE DAGSTKGKGH LVKPPYSYIA
LITMAILHSA EKKLTLSGIC EFIKNRFPFY RDKFPAWTNS IRHNLSLNDC FVKIAREAGN
PGKGNYWTLD PLSESMFDNG SFLRRRKRYK RQQTYPLKDS SAFMAATLDP YRHGLFAGHP
NLALGYPYMP HMPPPVPLLT TQDLARVTLH PIHLGAMHNP MVAPVCAGPP AIFDNPSDIT
STSTQCPKAM TSKPSFSIDR IIGDSKSPDV KPEMLTLRPN VPLLSHSPLD TAFATCPGST
LNAFEKYRQY LQTISSSAMD VNGTWSR
//
