ID A0A8X6KCC2_TRICU Unreviewed; 346 AA.
AC A0A8X6KCC2;
DT 14-DEC-2022, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2022, sequence version 1.
DT 28-JAN-2026, entry version 9.
DE SubName: Full=Bardet-Biedl syndrome 5 protein homolog {ECO:0000313|EMBL:GFQ67623.1};
GN Name=bbs5 {ECO:0000313|EMBL:GFQ67623.1};
GN ORFNames=TNCT_95931 {ECO:0000313|EMBL:GFQ67623.1};
OS Trichonephila clavata (Joro spider) (Nephila clavata).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Araneae;
OC Araneomorphae; Entelegynae; Araneoidea; Nephilidae; Trichonephila.
OX NCBI_TaxID=2740835 {ECO:0000313|EMBL:GFQ67623.1, ECO:0000313|Proteomes:UP000887116};
RN [1] {ECO:0000313|EMBL:GFQ67623.1}
RP NUCLEOTIDE SEQUENCE.
RA Kono N., Nakamura H., Mori M., Yoshida Y., Ohtoshi R., Malay A.D.,
RA Moran D.A.P., Tomita M., Numata K., Arakawa K.;
RT "Multicomponent nature underlies the extraordinary mechanical properties of
RT spider dragline silk.";
RL Submitted (JUL-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell projection, cilium membrane
CC {ECO:0000256|ARBA:ARBA00004309}. Cytoplasm, cytoskeleton, microtubule
CC organizing center, centrosome, centriolar satellite
CC {ECO:0000256|ARBA:ARBA00004607}.
CC -!- SIMILARITY: Belongs to the BBS5 family.
CC {ECO:0000256|ARBA:ARBA00005822}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GFQ67623.1}.
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DR EMBL; BMAO01020474; GFQ67623.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A8X6KCC2; -.
DR OrthoDB; 10261999at2759; -.
DR Proteomes; UP000887116; Unassembled WGS sequence.
DR GO; GO:0034464; C:BBSome; IEA:InterPro.
DR GO; GO:0034451; C:centriolar satellite; IEA:UniProtKB-SubCell.
DR GO; GO:0036064; C:ciliary basal body; IEA:TreeGrafter.
DR GO; GO:0060170; C:ciliary membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0032266; F:phosphatidylinositol-3-phosphate binding; IEA:TreeGrafter.
DR GO; GO:0060271; P:cilium assembly; IEA:TreeGrafter.
DR InterPro; IPR006606; BBL5.
DR InterPro; IPR030804; BBS5/fem-3.
DR InterPro; IPR014003; BBS5_PH.
DR PANTHER; PTHR21351:SF0; BARDET-BIEDL SYNDROME 5 PROTEIN; 1.
DR PANTHER; PTHR21351; BARDET-BIEDL SYNDROME PROTEIN 5; 1.
DR Pfam; PF07289; BBL5; 1.
DR PIRSF; PIRSF010072; DUF1448; 1.
DR SMART; SM00683; DM16; 2.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Cilium {ECO:0000256|ARBA:ARBA00023069};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000887116}.
FT DOMAIN 30..84
FT /note="BBSome complex member BBS5 PH"
FT /evidence="ECO:0000259|SMART:SM00683"
FT DOMAIN 160..214
FT /note="BBSome complex member BBS5 PH"
FT /evidence="ECO:0000259|SMART:SM00683"
SQ SEQUENCE 346 AA; 39375 MW; 43261AD6751E457A CRC64;
MAVNKVEPLW QDRDIKFDLS PAEMNFHCGE KLIDKLDSVE DTKGNSGDAG KLFITNLRLI
WQSYVKPRVS LSVGFNCVTN MSTRTVNSKL RGMTEALYIL TKVHSTRFEF IFTNLIPGTT
RLMTSVMSVY KAYNSSKWYR ELKLRGSVVL SKQLKVLPQE QIYSKVNGVW NLSSDQGNLG
TFFITNIRLV WHANMNELFN ISIPYIQIVS LKVRESKFGM ALVVESSENS GGYVLGFKID
PLERLQEVFK EISSLYQVHS TNPILGVDFF IEEKVIVDNE IPQCAPIDED VEIINSKECD
TFAAYFADEN HLKDREPVYC EELGLAVEKI KDGFTMSSLW EVIPSS
//
