ID   A0A8X6XUC2_9ARAC        Unreviewed;       661 AA.
AC   A0A8X6XUC2;
DT   14-DEC-2022, integrated into UniProtKB/TrEMBL.
DT   14-DEC-2022, sequence version 1.
DT   28-JAN-2026, entry version 14.
DE   SubName: Full=E3 ubiquitin-protein ligase TTC3 {ECO:0000313|EMBL:GFY59679.1};
GN   Name=Ttc3 {ECO:0000313|EMBL:GFY59679.1};
GN   ORFNames=TNIN_241032 {ECO:0000313|EMBL:GFY59679.1};
OS   Trichonephila inaurata madagascariensis.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Araneae;
OC   Araneomorphae; Entelegynae; Araneoidea; Nephilidae; Trichonephila;
OC   Trichonephila inaurata.
OX   NCBI_TaxID=2747483 {ECO:0000313|EMBL:GFY59679.1, ECO:0000313|Proteomes:UP000886998};
RN   [1] {ECO:0000313|EMBL:GFY59679.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Kono N., Nakamura H., Mori M., Yoshida Y., Ohtoshi R., Malay A.D.,
RA   Moran D.A.P., Tomita M., Numata K., Arakawa K.;
RT   "Multicomponent nature underlies the extraordinary mechanical properties of
RT   spider dragline silk.";
RL   Submitted (AUG-2020) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GFY59679.1}.
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DR   EMBL; BMAV01012741; GFY59679.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A8X6XUC2; -.
DR   Proteomes; UP000886998; Unassembled WGS sequence.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR043866; TTC3/DZIP3_dom.
DR   PANTHER; PTHR17550; E3 UBIQUITIN-PROTEIN LIGASE TTC3; 1.
DR   PANTHER; PTHR17550:SF4; E3 UBIQUITIN-PROTEIN LIGASE TTC3; 1.
DR   Pfam; PF19179; TTC3_DZIP3_dom; 1.
DR   SUPFAM; SSF48452; TPR-like; 2.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000886998}.
FT   DOMAIN          540..649
FT                   /note="E3 ubiquitin-protein ligase TTC3/DZIP3"
FT                   /evidence="ECO:0000259|Pfam:PF19179"
FT   REGION          353..384
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        356..366
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   661 AA;  75598 MW;  F7CB7BAD33C824F5 CRC64;
     MFQGLDTTSV YDRCIAAGLC MAHRKELKAY DDNKSQEIQR KALLYIRLQI FSPLLHQRPF
     CCEKLRVLFA KAECFSPKEN QENHDEFLDR LLVLDSIAVF LLCHFCKICC AGAFFESGPR
     AHIRPESEKD IFLKLLTHTT IDEKDIGLLT PLLENFKDVS DVILKVSYVA VLLYVRNISV
     KIDINEAVRH IDENMKKDGE ECLRWEAVGG EAMKRLNWEE AFEAYSVALN FKPYCSSLLV
     HRSRSLTKMW RLKDAFMDGY LAATFDPSNI NGYLRMVIAL SMLQDFMFCA NVADYCLYKC
     SGSTEILKLR TVEEFKDKAE IALIEIAPGL ANEHIAKLEK RALARRNIND LPELIEPSDS
     DSDCEDAPAP MEASNSDESD SNIDCSKPEI NGCPNGSLKI VEDEVKVLQE SLKEASQTLL
     NGHEVMAMRR FRDALDEIKG SPEIHKYEEC DIICIKYAYA FACYKSGGYD NTLKAITILK
     EITEKNKSIV FPAVYYCIGL AYLKIYRFKL ALENFRIVDD MLQKKVQCNS FVWPGLVTVI
     EETKLDHLKS VLPDLIKECE NPPLPNATCR YEDCSLQPSI YYSDPDFKGL YCIHCSEHCY
     LQYHVQCWKS IRTLANHIDK EFLDKKCYTP DCEGVIVHIQ IINKEGDVVK EVNFKFISIA
     T
//