ID A0A8X7ZE03_POPTO Unreviewed; 426 AA.
AC A0A8X7ZE03;
DT 14-DEC-2022, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2022, sequence version 1.
DT 28-JAN-2026, entry version 10.
DE RecName: Full=Radical SAM core domain-containing protein {ECO:0000259|PROSITE:PS51918};
GN ORFNames=POTOM_028791 {ECO:0000313|EMBL:KAG6767581.1};
OS Populus tomentosa (Chinese white poplar).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Malpighiales; Salicaceae; Saliceae; Populus.
OX NCBI_TaxID=118781 {ECO:0000313|EMBL:KAG6767581.1, ECO:0000313|Proteomes:UP000886885};
RN [1] {ECO:0000313|EMBL:KAG6767581.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=GM15 {ECO:0000313|EMBL:KAG6767581.1};
RC TISSUE=Leaf {ECO:0000313|EMBL:KAG6767581.1};
RA An X., Gao K., Chen Z., Li J., Yang X., Yang X., Zhou J., Guo T., Zhao T.,
RA Huang S., Miao D., Khan W.U., Rao P., Ye M., Lei B., Liao W., Wang J.,
RA Ji L., Li Y., Guo B., Mustafa N.S., Li S., Yun Q., Keller S.R., Mao J.,
RA Zhang R., Strauss S.H.;
RT "Hybrid origin of Populus tomentosa Carr. identified through genome
RT sequencing and phylogenomic analysis.";
RL bioRxiv 0:0-0(2020).
CC -!- COFACTOR:
CC Name=[2Fe-2S] cluster; Xref=ChEBI:CHEBI:190135;
CC Evidence={ECO:0000256|ARBA:ARBA00034078};
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAG6767581.1}.
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DR EMBL; JAAWWB010000014; KAG6767581.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A8X7ZE03; -.
DR OrthoDB; 2414104at2759; -.
DR Proteomes; UP000886885; Chromosome 7D.
DR GO; GO:0005739; C:mitochondrion; IEA:TreeGrafter.
DR GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:TreeGrafter.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0004076; F:biotin synthase activity; IEA:InterPro.
DR GO; GO:0009102; P:biotin biosynthetic process; IEA:InterPro.
DR CDD; cd01335; Radical_SAM; 1.
DR HAMAP; MF_01694; BioB; 1.
DR InterPro; IPR010722; BATS_dom.
DR InterPro; IPR002684; Biotin_synth/BioAB.
DR InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR InterPro; IPR007197; rSAM.
DR NCBIfam; TIGR00433; bioB; 1.
DR PANTHER; PTHR22976; BIOTIN SYNTHASE; 1.
DR PANTHER; PTHR22976:SF2; BIOTIN SYNTHASE, MITOCHONDRIAL; 1.
DR Pfam; PF06968; BATS; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDG01060; BATS_domain_containing; 1.
DR SFLD; SFLDS00029; Radical_SAM; 1.
DR SMART; SM00876; BATS; 1.
DR SMART; SM00729; Elp3; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00022485};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00022485};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022485};
KW Reference proteome {ECO:0000313|Proteomes:UP000886885}.
FT DOMAIN 77..350
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 426 AA; 47183 MW; 3E128B8931B5E74E CRC64;
MLSIRSIFRS QPRLSSVTLS SLCYSSSSAA AIQAEKAIKD GPRNDWTRQE IKEVYDSPLL
DLLFHGAQVH RYAHNFREVQ QCTLLSIKTG GCSEDCSYCP QSSRYNTGLK AQRLMTKETV
IEAAKRAKEA GSTRFCMGAA WRDTIGRKTN FNQILDYVKE ISAKGLFPSC VSTEVSCQER
ELEKFLHLEL FKMKAYMLAH AFKVAMDMGM EVCCTLGMLE KQQAVELKKA GLTAYNHNLD
TSREYYPNII TTRSYDERLE TLEHVREAGI SVCSGGIIGL GEAEEDRVGL LHTLATLPTH
PESVPINALV AVKGTPLQEQ KPVEIWEMIR MIGSARIVMP KAMVRLSAGR VRFSMAEQAL
CFLAGANSIF TGEKLLTTPN NDYDADQLMF KVLGLIPKSP SFSAAEEKAC ACEAEHCQEA
VSSSSG
//
