ID A0A8X8YBF9_SALSN Unreviewed; 320 AA.
AC A0A8X8YBF9;
DT 14-DEC-2022, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2022, sequence version 1.
DT 28-JAN-2026, entry version 12.
DE RecName: Full=RING-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012483};
DE EC=2.3.2.27 {ECO:0000256|ARBA:ARBA00012483};
GN ORFNames=SASPL_107509 {ECO:0000313|EMBL:KAG6429458.1};
OS Salvia splendens (Scarlet sage).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Lamiales; Lamiaceae; Nepetoideae; Mentheae; Salviinae;
OC Salvia; Salvia subgen. Calosphace; core Calosphace.
OX NCBI_TaxID=180675 {ECO:0000313|EMBL:KAG6429458.1};
RN [1] {ECO:0000313|EMBL:KAG6429458.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Huo1 {ECO:0000313|EMBL:KAG6429458.1};
RC TISSUE=Leaf {ECO:0000313|EMBL:KAG6429458.1};
RA Mao J.F.;
RL Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KAG6429458.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Huo1 {ECO:0000313|EMBL:KAG6429458.1};
RC TISSUE=Leaf {ECO:0000313|EMBL:KAG6429458.1};
RA Zhang R.-G.;
RT "Plant Genome Project.";
RL Submitted (AUG-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.;
CC EC=2.3.2.27; Evidence={ECO:0000256|ARBA:ARBA00000900};
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- SIMILARITY: Belongs to the SINA (Seven in absentia) family.
CC {ECO:0000256|ARBA:ARBA00009119}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAG6429458.1}.
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DR EMBL; PNBA02000003; KAG6429458.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A8X8YBF9; -.
DR OrthoDB; 941555at2759; -.
DR Proteomes; UP000298416; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR CDD; cd16571; RING-HC_SIAHs; 1.
DR CDD; cd03829; Sina; 1.
DR FunFam; 3.30.40.10:FF:000041; E3 ubiquitin-protein ligase SINAT3; 1.
DR FunFam; 2.60.210.10:FF:000004; E3 ubiquitin-protein ligase SINAT5-like; 1.
DR Gene3D; 2.60.210.10; Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2, Chain A; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR018121; 7-in-absentia-prot_TRAF-dom.
DR InterPro; IPR052088; E3_ubiquitin-ligase_SINA.
DR InterPro; IPR049548; Sina-like_RING.
DR InterPro; IPR008974; TRAF-like.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR013010; Znf_SIAH.
DR PANTHER; PTHR10315; E3 UBIQUITIN PROTEIN LIGASE SIAH; 1.
DR PANTHER; PTHR10315:SF80; E3 UBIQUITIN-PROTEIN LIGASE SINAT3; 1.
DR Pfam; PF21362; Sina_RING; 1.
DR Pfam; PF03145; Sina_TRAF; 1.
DR Pfam; PF21361; Sina_ZnF; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF49599; TRAF domain-like; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
DR PROSITE; PS51081; ZF_SIAH; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000298416};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00455}.
FT DOMAIN 59..95
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 112..172
FT /note="SIAH-type"
FT /evidence="ECO:0000259|PROSITE:PS51081"
SQ SEQUENCE 320 AA; 36227 MW; 6A2B69CCD25ACB57 CRC64;
MAALEIDSVE CVSSIDGNED EEIVSHTKQH DLPHQYSSKP HGAVAVGLVP TSVHELLECP
VCTNSMYPPI HQCHNGHTLC STCKSRVHNR CPTCRQELGD IRCLALEKVA ESLELPCKFF
SLGCAEIFPY YSKLKHEAVC NFRPHNCPYA GSECSVTGDI PFLVAHLRDD HKVDMHTGST
FNHRYVKSNP REVENATWML TVFNCFGQYF CLHFEAFQLG MAPVYMAFLR FMGDETEARN
YSYSLEVGAN GRKLIWEGTP RSIRCSHRKV RDSHDGLIIQ RNMALFFSGD KKELKLRVTG
RIWKEQQNPD TGVCIPNLSI
//
