ID A0A913X7K4_EXADI Unreviewed; 1599 AA.
AC A0A913X7K4;
DT 22-FEB-2023, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2023, sequence version 1.
DT 28-JAN-2026, entry version 12.
DE RecName: Full=Fibronectin type-III domain-containing protein {ECO:0000259|PROSITE:PS50853};
OS Exaiptasia diaphana (Tropical sea anemone) (Aiptasia pulchella).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC Aiptasiidae; Exaiptasia.
OX NCBI_TaxID=2652724 {ECO:0000313|EnsemblMetazoa:XP_020899697.1, ECO:0000313|Proteomes:UP000887567};
RN [1] {ECO:0000313|EnsemblMetazoa:XP_020899697.1}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (NOV-2022) to UniProtKB.
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DR RefSeq; XP_020899697.1; XM_021044038.2.
DR EnsemblMetazoa; XM_021044038.2; XP_020899697.1; LOC110238366.
DR GeneID; 110238366; -.
DR KEGG; epa:110238366; -.
DR OMA; KEINCDK; -.
DR OrthoDB; 10060752at2759; -.
DR Proteomes; UP000887567; Unplaced.
DR GO; GO:0005581; C:collagen trimer; IEA:UniProtKB-KW.
DR GO; GO:0031012; C:extracellular matrix; IEA:TreeGrafter.
DR GO; GO:0005615; C:extracellular space; IEA:TreeGrafter.
DR GO; GO:0030020; F:extracellular matrix structural constituent conferring tensile strength; IEA:TreeGrafter.
DR GO; GO:0030198; P:extracellular matrix organization; IEA:TreeGrafter.
DR CDD; cd00063; FN3; 1.
DR FunFam; 2.60.40.10:FF:000028; Neuronal cell adhesion molecule; 1.
DR Gene3D; 3.40.1620.70; -; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 3.10.100.10; Mannose-Binding Protein A, subunit A; 1.
DR InterPro; IPR016186; C-type_lectin-like/link_sf.
DR InterPro; IPR008160; Collagen.
DR InterPro; IPR050149; Collagen_superfamily.
DR InterPro; IPR010515; Collagenase_NC10/endostatin.
DR InterPro; IPR016187; CTDL_fold.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR045463; XV/XVIII_trimerization_dom.
DR PANTHER; PTHR24023; COLLAGEN ALPHA; 1.
DR PANTHER; PTHR24023:SF1082; COLLAGEN TRIPLE HELIX REPEAT; 1.
DR Pfam; PF01391; Collagen; 5.
DR Pfam; PF20010; Collagen_trimer; 1.
DR Pfam; PF06482; Endostatin; 1.
DR Pfam; PF00041; fn3; 1.
DR SMART; SM00060; FN3; 1.
DR SUPFAM; SSF56436; C-type lectin-like; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR PROSITE; PS50853; FN3; 1.
PE 4: Predicted;
KW Collagen {ECO:0000256|ARBA:ARBA00023119};
KW Reference proteome {ECO:0000313|Proteomes:UP000887567};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 251..343
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 416..464
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 480..1340
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 432..441
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 443..464
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 546..561
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 592..601
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 619..634
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 639..651
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 734..743
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 774..794
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 802..815
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 893..920
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 940..949
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 983..1010
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1049..1062
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1076..1085
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1088..1110
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1177..1190
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1255..1273
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1297..1323
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1599 AA; 159007 MW; 66D186CA6B82B100 CRC64;
MSTSVPDVTT GDISTSAPGV TTGDISTGAA SVTTGDMTPS AAGVTTGDMS TASPAVTTGD
LSSSALGVTT GDISTGAASV TTGVMTPSAA GVTTGDMSSV SPAVSTGNMT RASTFASIPP
TPSSITTEEK TIKTTIYTKD WSVTITLSVV LPDLKXIHEN LSPSSELYRL LSKPILTNVE
KFASNFESFV YAKLISVSRR SGSAVATVEL RFSSLKKNEL IDLVEVLEDN RAIEELAVGS
SNITADKVPS APIGVQVHSI SPTVAKVLWE PIALNSRHXS LLGYKVYYRA ANSKKWNTAS
CNCTNVSVKN LKPNVKYRIR VFALTTNGNG IPSPALEVIT GQGIGAAATT VKPISTAPSC
AVTCPKGEKG DRGSIGLPGL PGQTVYLSSN NGTVHLVKGS KGEPGSCSTN CSSMLKIRGP
KGEPGKSIVG PPGKPGNPGP PGVSGQPGAS GLPGTPGAPG LPATYINMTT GEVIRILQGQ
KGQQGFNGSK GETGFKGDKG ITGSDGXKGE KGQDGRPGPQ GKRGLIGLPG KSLPGPQGKP
GPVGIKGEKG DPGAPKGEKG SEGPPGSIGI KGDKGESVTG PPGPPGPPGD GSITNGHSTC
SCPPGPKGVT GLTGQSGRDG LKGESGEKGQ KGEIGEPGIP APISPPFPGP PGLKGVKGEP
GDPGYPGLRG EIGLQGPPGF KGESGQVGIK GTPGIPGTKG DRGNAGRIGF PGIKGSPGEP
GPVGPTGAAG KSGGKGEKGE RGIKGATGTN GLKGEPGVPG IQGEQGVIGS AGEKGAKGDR
GLAGIKGEKG DEGIGIKGAQ GSPGTSGTQG PRGRQGPPGP PGLVAFVKGA KGEIGLTGKP
GTPGEKGNEG DEGQKGSQGI KGEQGSKGEV GATGPRGKPG LVIPGPSGPQ GPPGSKGSSG
EKGSTGEAGL KGPIGPPGLK GSKGEIGPVG PKGKSIQGXP GPPGPPGPPG LITEVLIPGQ
GQQKGGVSKG QKGNPGRPGF PGQPGTDGEP GEPGLXGPPG DLGPQGLEGP IGQKGRKGEI
GSPGKQGLQG IAGRPGQKGA VGPQGDRGLS GPPGIPGQSG PSGDKGTRGA VGPAGERGEK
GDKGESGQPG PAGAQGQKGT AGKQGPQGPV GLPGPQGPPG LDGEAGRKGE KGNQGFGVKG
IKGEKGSMGP RGANGFPGRK GAKGDFGQSG LPGPAGEPGV SGLPGSVGPP GRKGERGDTG
PIGIRGEKGE VGSPGVPGKD GLVGIPGQTG VKGEAGDRGN DGANGAKGDK GTKGQDGQPG
VKGSPGDVTT VVGPPGPPGP PGLSTIKNEN GTIIRGPPGP PGPKSLIPGP PGPPGPPGSP
GPPGDSKRSV GKTPVDIPGM KTMEHGVVTF DSLNNMIQSA PAVFAGTIAF VLSEQRLYVK
TSTGWRLVLV GPLVIGQTPT DQIYVTQEPS NGMLILPQPG IRLTGRYLRL IALNYPITGQ
MGTLAGIDGQ CWKQSRKAGF IGGFRAFLSN TLQHIYTVVP RGERDLPVAN LKGEQIFSSW
RKLFAKHLAF NPKTPIYSFD GEDVNKSKRW STKYFWHGSK NDGRKAEENC GSWQSRSGKD
LSTASALDGS SAILDEQYYT CDNRFAVLCI QTSHNTFRK
//
