ID A0A913XGF2_EXADI Unreviewed; 341 AA.
AC A0A913XGF2;
DT 22-FEB-2023, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2023, sequence version 1.
DT 28-JAN-2026, entry version 12.
DE RecName: Full=BBSome complex member BBS5 {ECO:0000256|ARBA:ARBA00047191};
OS Exaiptasia diaphana (Tropical sea anemone) (Aiptasia pulchella).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC Aiptasiidae; Exaiptasia.
OX NCBI_TaxID=2652724 {ECO:0000313|EnsemblMetazoa:XP_020903821.1, ECO:0000313|Proteomes:UP000887567};
RN [1] {ECO:0000313|EnsemblMetazoa:XP_020903821.1}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (NOV-2022) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell projection, cilium membrane
CC {ECO:0000256|ARBA:ARBA00004309}. Cytoplasm, cytoskeleton, microtubule
CC organizing center, centrosome, centriolar satellite
CC {ECO:0000256|ARBA:ARBA00004607}.
CC -!- SIMILARITY: Belongs to the BBS5 family.
CC {ECO:0000256|ARBA:ARBA00005822}.
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DR RefSeq; XP_020903821.1; XM_021048162.2.
DR AlphaFoldDB; A0A913XGF2; -.
DR EnsemblMetazoa; XM_021048162.2; XP_020903821.1; LOC110242205.
DR GeneID; 110242205; -.
DR KEGG; epa:110242205; -.
DR OMA; PNFGIQY; -.
DR OrthoDB; 10261999at2759; -.
DR Proteomes; UP000887567; Unplaced.
DR GO; GO:0034464; C:BBSome; IEA:InterPro.
DR GO; GO:0034451; C:centriolar satellite; IEA:UniProtKB-SubCell.
DR GO; GO:0036064; C:ciliary basal body; IEA:TreeGrafter.
DR GO; GO:0060170; C:ciliary membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0032266; F:phosphatidylinositol-3-phosphate binding; IEA:TreeGrafter.
DR GO; GO:0060271; P:cilium assembly; IEA:TreeGrafter.
DR FunFam; 2.30.29.30:FF:000232; Bardet-Biedl syndrome 5 isoform 1; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR006606; BBL5.
DR InterPro; IPR030804; BBS5/fem-3.
DR InterPro; IPR014003; BBS5_PH.
DR InterPro; IPR011993; PH-like_dom_sf.
DR PANTHER; PTHR21351:SF0; BARDET-BIEDL SYNDROME 5 PROTEIN; 1.
DR PANTHER; PTHR21351; BARDET-BIEDL SYNDROME PROTEIN 5; 1.
DR Pfam; PF07289; BBL5; 1.
DR PIRSF; PIRSF010072; DUF1448; 1.
DR SMART; SM00683; DM16; 2.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Cilium {ECO:0000256|ARBA:ARBA00023069};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000887567}.
FT DOMAIN 27..81
FT /note="BBSome complex member BBS5 PH"
FT /evidence="ECO:0000259|SMART:SM00683"
FT DOMAIN 157..211
FT /note="BBSome complex member BBS5 PH"
FT /evidence="ECO:0000259|SMART:SM00683"
SQ SEQUENCE 341 AA; 38739 MW; 91CF9BD4B3969F8F CRC64;
MADCNLWEDR DVRFDITLQQ MQLRSGEILI DKLDSVEDTK GNNGDRGRLM VTNLRLIWHS
QSMPRVNLSV GYGAVVNIST RTAHSKLRGQ TEALYLLTRC NNTRFEFIFT NLVSGSPRLF
TTVISVYRAY ESSKLYRDLK LRGALIQNKQ LRILPLEQVY DKINGVWNLS SDQGNLGTFY
ITNVRLVWHA NMNDSFNVSI PYLQMKTVRI RDSKFGLALV VETSQQSGGY VLGFRIDPVE
KLQEAVKEIQ SLQKVYSASP IFGVEFETED KPQALEEVTV DPVQDDIEIV NEGTTDAFAA
YFADGDKTSD REPIYSEQLG LAIEKLKDGF TLQELWEAVP N
//
