ID A0A914NY01_9BILA Unreviewed; 473 AA.
AC A0A914NY01;
DT 22-FEB-2023, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2023, sequence version 1.
DT 27-NOV-2024, entry version 10.
DE RecName: Full=phospholipase D {ECO:0000256|ARBA:ARBA00012027};
DE EC=3.1.4.4 {ECO:0000256|ARBA:ARBA00012027};
OS Panagrolaimus davidi.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Tylenchina; Panagrolaimomorpha; Panagrolaimoidea; Panagrolaimidae;
OC Panagrolaimus.
OX NCBI_TaxID=227884 {ECO:0000313|Proteomes:UP000887578, ECO:0000313|WBParaSite:PDA_v2.g10332.t1};
RN [1] {ECO:0000313|WBParaSite:PDA_v2.g10332.t1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (NOV-2022) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1,2-diacyl-
CC sn-glycero-3-phosphate + choline + H(+); Xref=Rhea:RHEA:14445,
CC ChEBI:CHEBI:15354, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:57643, ChEBI:CHEBI:58608; EC=3.1.4.4;
CC Evidence={ECO:0000256|ARBA:ARBA00000798};
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DR WBParaSite; PDA_v2.g10332.t1; PDA_v2.g10332.t1; PDA_v2.g10332.
DR Proteomes; UP000887578; Unplaced.
DR GO; GO:0043231; C:intracellular membrane-bounded organelle; IEA:TreeGrafter.
DR GO; GO:0004630; F:phospholipase D activity; IEA:TreeGrafter.
DR GO; GO:0009395; P:phospholipid catabolic process; IEA:TreeGrafter.
DR GO; GO:0060627; P:regulation of vesicle-mediated transport; IEA:TreeGrafter.
DR Gene3D; 3.30.870.10; Endonuclease Chain A; 3.
DR InterPro; IPR001736; PLipase_D/transphosphatidylase.
DR InterPro; IPR015679; PLipase_D_fam.
DR PANTHER; PTHR18896:SF76; PHOSPHOLIPASE; 1.
DR PANTHER; PTHR18896; PHOSPHOLIPASE D; 1.
DR Pfam; PF00614; PLDc; 1.
DR SMART; SM00155; PLDc; 1.
DR SUPFAM; SSF56024; Phospholipase D/nuclease; 3.
DR PROSITE; PS50035; PLD; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Lipid degradation {ECO:0000256|ARBA:ARBA00022963};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Reference proteome {ECO:0000313|Proteomes:UP000887578}.
FT DOMAIN 10..37
FT /note="PLD phosphodiesterase"
FT /evidence="ECO:0000259|PROSITE:PS50035"
SQ SEQUENCE 473 AA; 54592 MW; 560A4F411347E402 CRC64;
MYHGHCHATF LWTHHEKFIV VDQLIAFVGG IDLTYGRWDD HRHVLSDLGY VDVLPSIKNE
QTESIESALT SAVDAATKAI IADTNLSELR KNKRKPHRRI ELLFLKLGGE CLEKNAFSIT
QSEQQNGKRM FKLSKLKGPK NVFEEDLSEA AIDGTEFHNA EDVSFTVDSD KVTLLTPLDS
TEKDISKEKP QLSNYSKILS NSIIQTYQKT IPEGTDLIRI SVINPDPYEI HETTAHTFGG
THSYSKNPFR RLYENIAIQL RRLAFSRESK TIEEYVINFY VIQKQQVEIG KKENAGKLFP
GKDYVNFIFK DIVDADDAFS DFTDRYNMPR MPWHDSQTGT YGEAARDVAR HFIQRWNAAK
REKLRNNDAY PYLIPKSYDN IRVPSAIINE DMYKTEVQVL RSVTRWSALT DKTEDSIHQA
YISLMENAKH YIYIENQFFV SMINNADVSN EISKTICDRI IRAHRYVLSL IIR
//
