ID A0A914WP82_9BILA Unreviewed; 415 AA.
AC A0A914WP82;
DT 22-FEB-2023, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2023, sequence version 1.
DT 28-JAN-2026, entry version 12.
DE RecName: Full=Proteasomal ubiquitin receptor ADRM1 homolog {ECO:0000256|ARBA:ARBA00070663};
OS Plectus sambesii.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Plectida; Plectina;
OC Plectoidea; Plectidae; Plectus.
OX NCBI_TaxID=2011161 {ECO:0000313|Proteomes:UP000887566, ECO:0000313|WBParaSite:PSAMB.scaffold4783size13524.g25153.t1};
RN [1] {ECO:0000313|WBParaSite:PSAMB.scaffold4783size13524.g25153.t1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (NOV-2022) to UniProtKB.
CC -!- FUNCTION: May function as a proteasomal ubiquitin receptor. May promote
CC the deubiquitinating activity associated with the 26S proteasome.
CC {ECO:0000256|ARBA:ARBA00054744}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the ADRM1 family.
CC {ECO:0000256|ARBA:ARBA00009216}.
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DR AlphaFoldDB; A0A914WP82; -.
DR WBParaSite; PSAMB.scaffold4783size13524.g25153.t1; PSAMB.scaffold4783size13524.g25153.t1; PSAMB.scaffold4783size13524.g25153.
DR Proteomes; UP000887566; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0008541; C:proteasome regulatory particle, lid subcomplex; IEA:TreeGrafter.
DR GO; GO:0061133; F:endopeptidase activator activity; IEA:TreeGrafter.
DR GO; GO:0070628; F:proteasome binding; IEA:TreeGrafter.
DR CDD; cd13314; PH_Rpn13; 1.
DR FunFam; 2.30.29.70:FF:000001; Proteasomal ubiquitin receptor ADRM1; 1.
DR Gene3D; 1.10.2020.20; -; 1.
DR Gene3D; 2.30.29.70; Proteasomal ubiquitin receptor Rpn13/ADRM1; 1.
DR InterPro; IPR044867; DEUBAD_dom.
DR InterPro; IPR006773; Rpn13/ADRM1.
DR InterPro; IPR044868; Rpn13/ADRM1_Pru.
DR InterPro; IPR038633; Rpn13/ADRM1_Pru_sf.
DR InterPro; IPR032368; RPN13_DEUBAD.
DR InterPro; IPR038108; RPN13_DEUBAD_sf.
DR PANTHER; PTHR12225; ADHESION REGULATING MOLECULE 1 110 KDA CELL MEMBRANE GLYCOPROTEIN; 1.
DR PANTHER; PTHR12225:SF0; PROTEASOMAL UBIQUITIN RECEPTOR ADRM1; 1.
DR Pfam; PF04683; Rpn13_ADRM1_Pru; 1.
DR Pfam; PF16550; RPN13_C; 1.
DR PROSITE; PS51916; DEUBAD; 1.
DR PROSITE; PS51917; PRU; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Proteasome {ECO:0000256|ARBA:ARBA00022942};
KW Reference proteome {ECO:0000313|Proteomes:UP000887566}.
FT DOMAIN 13..132
FT /note="Pru"
FT /evidence="ECO:0000259|PROSITE:PS51917"
FT DOMAIN 261..374
FT /note="DEUBAD"
FT /evidence="ECO:0000259|PROSITE:PS51916"
FT REGION 210..240
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 353..415
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 353..366
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 380..391
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 396..409
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 415 AA; 44078 MW; 6B7C4A0651CF3043 CRC64;
MTAMFANTRS SQQSSGYLVE FKAGKSALSA GSTPDKRKVV ADKTKGQVFI KQSNDQLMHF
CWKNRETGAV VDDLIIFPGD TEFLRVKECP DGRVFVLKFK NSDRRCFFWL QEGKTDKDDE
YCRKVNDLLN NPPTRSVGRG GGDRADQLAG LGLGGAEDLG ALGNLDQGQL MQLLSLMGQG
GGGLDPATAS ALLPQLGLGG GSDGGISSTP LTTNVTPATA ATSTPPTGRT GRGRTQQGQT
TAPIQLSELQ NIISSISVPQ GQGPAGREIS LESVMTGENL QEAVRSEGNE ARLLPLLPTE
APVEQNREEL QQTIRAPQFR QATEIFGHAL QTGQLGPVLQ QFGVNPEAVE AASRGDMEKF
AEKLTEAEGG PKAADEKNPS GSGSSESGQG DSSEDATVRE PEPKRGKTDD EMDLD
//
