ID A0A914YI93_9BILA Unreviewed; 370 AA.
AC A0A914YI93;
DT 22-FEB-2023, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2023, sequence version 1.
DT 18-JUN-2025, entry version 12.
DE RecName: Full=Ribosome assembly factor mrt4 {ECO:0000256|RuleBase:RU364039};
OS Panagrolaimus superbus.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Tylenchina; Panagrolaimomorpha; Panagrolaimoidea; Panagrolaimidae;
OC Panagrolaimus.
OX NCBI_TaxID=310955 {ECO:0000313|Proteomes:UP000887577, ECO:0000313|WBParaSite:PSU_v2.g20054.t1};
RN [1] {ECO:0000313|WBParaSite:PSU_v2.g20054.t1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (NOV-2022) to UniProtKB.
CC -!- FUNCTION: Component of the ribosome assembly machinery. Nuclear paralog
CC of the ribosomal protein P0, it binds pre-60S subunits at an early
CC stage of assembly in the nucleolus, and is replaced by P0 in
CC cytoplasmic pre-60S subunits and mature 80S ribosomes.
CC {ECO:0000256|ARBA:ARBA00004046, ECO:0000256|RuleBase:RU364039}.
CC -!- SUBUNIT: Associates with the pre-60S ribosomal particle.
CC {ECO:0000256|ARBA:ARBA00011117, ECO:0000256|RuleBase:RU364039}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|RuleBase:RU364039}.
CC Nucleus, nucleolus {ECO:0000256|RuleBase:RU364039}.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uL10 family.
CC {ECO:0000256|ARBA:ARBA00008889, ECO:0000256|RuleBase:RU364039}.
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DR WBParaSite; PSU_v2.g20054.t1; PSU_v2.g20054.t1; PSU_v2.g20054.
DR Proteomes; UP000887577; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0030687; C:preribosome, large subunit precursor; IEA:TreeGrafter.
DR GO; GO:0003723; F:RNA binding; IEA:TreeGrafter.
DR GO; GO:0000956; P:nuclear-transcribed mRNA catabolic process; IEA:TreeGrafter.
DR GO; GO:0000027; P:ribosomal large subunit assembly; IEA:InterPro.
DR GO; GO:0006364; P:rRNA processing; IEA:TreeGrafter.
DR CDD; cd05796; Ribosomal_P0_like; 1.
DR FunFam; 3.30.70.1730:FF:000005; Ribosome assembly factor mrt4; 1.
DR FunFam; 3.90.105.20:FF:000003; Ribosome assembly factor mrt4; 1.
DR Gene3D; 3.30.70.1730; -; 1.
DR Gene3D; 3.90.105.20; -; 1.
DR InterPro; IPR033867; Mrt4.
DR InterPro; IPR001790; Ribosomal_uL10.
DR InterPro; IPR040637; Ribosomal_uL10-like_insert.
DR InterPro; IPR043164; Ribosomal_uL10-like_insert_sf.
DR InterPro; IPR043141; Ribosomal_uL10-like_sf.
DR InterPro; IPR051742; Ribosome_Assembly_uL10.
DR PANTHER; PTHR45841:SF1; MRNA TURNOVER PROTEIN 4 HOMOLOG; 1.
DR PANTHER; PTHR45841; MRNA TURNOVER PROTEIN 4 MRTO4; 1.
DR Pfam; PF00466; Ribosomal_L10; 1.
DR Pfam; PF17777; RL10P_insert; 1.
DR SUPFAM; SSF160369; Ribosomal protein L10-like; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|RuleBase:RU364039};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU364039};
KW Reference proteome {ECO:0000313|Proteomes:UP000887577};
KW Ribosome biogenesis {ECO:0000256|RuleBase:RU364039}.
FT DOMAIN 126..195
FT /note="Large ribosomal subunit protein uL10-like insertion"
FT /evidence="ECO:0000259|Pfam:PF17777"
SQ SEQUENCE 370 AA; 42206 MW; 440CC6C779383A10 CRC64;
MPKSKRDKEI SLTKVKKKTR ENKNAVINRI QDALAQHKNI FVFSIDSMRS TKMTEIRQKF
KETSRFFYGK NTVMSVALGR DAATEKEKGL HKVSQLLKGQ CGLMFTNENG KNVIKFFKEY
SENDHARAGQ EVDEDISLEK GPLPQFAFSV EPQLRKLGLP TKLEKGVIEL VDDFTVCKAG
DKLNPEQAKI LKLLDHKLSH FQVNLIAHWS ADKGLTTLYY DTSANTFFKA STTAAFFSTT
TKCLKEVGKR EIRFSETAAY QGVDRRSFDL KSEWKPDYYQ THSYRTKKLL SALLSLTAVI
IWIGCIREES DLDAIFNTPP HLITAGLERK MLKEQIQKNK RDGKDTSLLQ AELEYVDVKE
AALKAQFSKK
//
