ID   A0A915AZ81_PARUN        Unreviewed;       724 AA.
AC   A0A915AZ81;
DT   22-FEB-2023, integrated into UniProtKB/TrEMBL.
DT   22-FEB-2023, sequence version 1.
DT   28-JAN-2026, entry version 15.
DE   SubName: Full=Peptidase S8/S53 domain-containing protein {ECO:0000313|WBParaSite:PgR021_g001_t02};
OS   Parascaris univalens (Nematode worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Ascaridomorpha; Ascaridoidea; Ascarididae; Parascaris.
OX   NCBI_TaxID=6257 {ECO:0000313|Proteomes:UP000887569, ECO:0000313|WBParaSite:PgR021_g001_t02};
RN   [1] {ECO:0000313|WBParaSite:PgR021_g001_t02}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2022) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the peptidase S8 family.
CC       {ECO:0000256|ARBA:ARBA00011073, ECO:0000256|PROSITE-ProRule:PRU01240}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC       feature annotation. {ECO:0000256|PROSITE-ProRule:PRU01240}.
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DR   AlphaFoldDB; A0A915AZ81; -.
DR   WBParaSite; PgR021_g001_t02; PgR021_g001_t02; PgR021_g001.
DR   Proteomes; UP000887569; Unplaced.
DR   GO; GO:0005794; C:Golgi apparatus; IEA:TreeGrafter.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR   InterPro; IPR057060; MBTPS1_3rd.
DR   InterPro; IPR057032; MBTPS1_4th.
DR   InterPro; IPR000209; Peptidase_S8/S53_dom.
DR   InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR   InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR   InterPro; IPR050131; Peptidase_S8_subtilisin-like.
DR   PANTHER; PTHR43806:SF7; MEMBRANE-BOUND TRANSCRIPTION FACTOR SITE-1 PROTEASE; 1.
DR   PANTHER; PTHR43806; PEPTIDASE S8; 1.
DR   Pfam; PF23094; MBTPS1_3rd; 1.
DR   Pfam; PF23090; MBTPS1_4th; 1.
DR   Pfam; PF00082; Peptidase_S8; 1.
DR   SUPFAM; SSF52743; Subtilisin-like; 1.
DR   PROSITE; PS51892; SUBTILASE; 1.
DR   PROSITE; PS00138; SUBTILASE_SER; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Protease {ECO:0000256|ARBA:ARBA00022670};
KW   Reference proteome {ECO:0000313|Proteomes:UP000887569};
KW   Serine protease {ECO:0000256|ARBA:ARBA00022825}.
FT   DOMAIN          7..147
FT                   /note="Peptidase S8/S53"
FT                   /evidence="ECO:0000259|Pfam:PF00082"
FT   DOMAIN          168..294
FT                   /note="MBTPS1 third"
FT                   /evidence="ECO:0000259|Pfam:PF23094"
FT   DOMAIN          295..564
FT                   /note="MBTPS1 fourth"
FT                   /evidence="ECO:0000259|Pfam:PF23090"
SQ   SEQUENCE   724 AA;  79955 MW;  BEECB80B1B954A03 CRC64;
     MDKVWELTAN GVILISAIGN DGPKFGTLNN PADQMDVIGV GGINMDSKVA RFSSRGMTTW
     ELPGGYGRVK PDIVTFGASV YGSALDGGCR ALSGTSVASP VVAGAVTLML SGIDDRRLWN
     PAVVKQALVE GAMRLPNAAT MFEQGAGRID LLASFDYMRK YKPSITLIPP YIDFTECPYM
     WPYCSQPLYV SSIPTIVNVT IVNGLGVSGR IIEPPVWEPF LDENGDLLKI AITYPDLLWP
     WSGYMAVAMS VAQDGISYEG TAAGRITITV TADEHGMKKR AVATFMVRVR IIPTPPRSQR
     IIWDQYRNMR YPPGYLPRDD LRDHANPLDW TADHPHTNFK ALYQHLRSSG YHIEVLGEPL
     TCVDLSDYAT YIVVDPEDEF FPSEREKLYL DVVDAGLNLV VFADWFNATV IDKIRFLDEN
     TKQWWQPETG GTNLPALNDL LSYWNITLGA QVFDGVVSLG RMTMKYSSGS SVVQTPFGSF
     VTKANLTDVG AETITGEKSS QLYEAAVFTF YRSVSTSKRR AGFVAVFGDS TCLEVGTSAD
     MRSCIPLLDA LLDSANEGQM SESLRRAVRS MEIRLPEGEP DAIALPRRII TSNFARYSKV
     ISALESDGSP VFRPQPKCKR FPMIVPHPIS NVTSPSDLNE GRRQNGQLDS FYDKIRSDAA
     AAQFNELDQF FDANTNLDRR AVSTNSVAFL GHPYISYLLW GSVVQNGRAF FRWSGSIQSA
     VTIF
//