ID A0A915U6T9_9BACT Unreviewed; 513 AA.
AC A0A915U6T9;
DT 22-FEB-2023, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2023, sequence version 1.
DT 28-JAN-2026, entry version 14.
DE SubName: Full=Selenobiotic family peptide radical SAM maturase {ECO:0000313|EMBL:BCO10567.1};
GN ORFNames=GF1_29430 {ECO:0000313|EMBL:BCO10567.1};
OS Desulfolithobacter dissulfuricans.
OC Bacteria; Pseudomonadati; Thermodesulfobacteriota; Desulfobulbia;
OC Desulfobulbales; Desulfobulbaceae; Desulfolithobacter.
OX NCBI_TaxID=2795293 {ECO:0000313|EMBL:BCO10567.1, ECO:0000313|Proteomes:UP001063350};
RN [1] {ECO:0000313|EMBL:BCO10567.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=GF1 {ECO:0000313|EMBL:BCO10567.1};
RA Hashimoto Y., Tame A., Sawayama S., Miyazaki J., Takai K., Nakagawa S.;
RT "Desulfobium dissulfuricans gen. nov., sp. nov., a novel mesophilic,
RT sulfate-reducing bacterium isolated from a deep-sea hydrothermal vent.";
RL Submitted (DEC-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AP024233; BCO10567.1; -; Genomic_DNA.
DR RefSeq; WP_267927295.1; NZ_AP024233.1.
DR AlphaFoldDB; A0A915U6T9; -.
DR KEGG; ddu:GF1_29430; -.
DR Proteomes; UP001063350; Chromosome.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd01335; Radical_SAM; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR023885; 4Fe4S-binding_SPASM_dom.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR InterPro; IPR023807; Peptide_mod_rSAM.
DR InterPro; IPR050377; Radical_SAM_PqqE_MftC-like.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR058240; rSAM_sf.
DR NCBIfam; TIGR04082; rSAM_for_selen; 1.
DR NCBIfam; TIGR04085; rSAM_more_4Fe4S; 1.
DR PANTHER; PTHR11228:SF7; PQQA PEPTIDE CYCLASE; 1.
DR PANTHER; PTHR11228; RADICAL SAM DOMAIN PROTEIN; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR Pfam; PF13186; SPASM; 1.
DR SFLD; SFLDS00029; Radical_SAM; 1.
DR SFLD; SFLDG01067; SPASM/twitch_domain_containing; 1.
DR SMART; SM00729; Elp3; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP001063350};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 191..404
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 513 AA; 58265 MW; 0BBAF3F48D1527BC CRC64;
MKKSSPENIY SACCRYLPPL PTVPDHDLVS WLADHPHLYT EHPFLPDLAR LEQALHFLRH
TPPPLPETVD RRQINPALEL LSLNWRQLSR LLDDPAIRPE PGQEFVLAVR KPDTGEVTVR
TATSHDLLAL KLVSEDMDER QTAREGGVPL ATIEAILYQA MEQGLILSPP SRIARPPDFP
RGEVSDPSFF TASVFTLQWH ITQTCDLHCR HCYDRSDRAT MELAQGIKIL DDLYDFAKAH
HVHAQVTFTG GNPLLYPHFN ELYREAAERG FLTAILGNPM PRHRLEEMLA VQKPEFYQVS
LEGLQPHNDY IRGPGHFERV LAFLDLLREL DIYSMVMLTL TRANMDEVLE LAELLRDRVD
LFTFNRLAMV GEGASLASAP FERFEQFLNR YMEACRDNPC MGLKDNFFNL VRHKKKMEYT
GGCAGYGCGA AFNFVSILPD GEVHACRKLP SPMGNIFENS LQEIYHSPQA RKYRRGSSAC
ADCAIRPVCG GCLAVTYGFG RDIFTELDPY CFR
//
