ID A0A916UKV3_9HYPH Unreviewed; 690 AA.
AC A0A916UKV3;
DT 22-FEB-2023, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2023, sequence version 1.
DT 28-JAN-2026, entry version 12.
DE RecName: Full=Selenocysteine-specific elongation factor {ECO:0000256|ARBA:ARBA00015953};
DE AltName: Full=SelB translation factor {ECO:0000256|ARBA:ARBA00031615};
GN Name=selB {ECO:0000313|EMBL:GGC75394.1};
GN ORFNames=GCM10010994_37310 {ECO:0000313|EMBL:GGC75394.1};
OS Chelatococcus reniformis.
OC Bacteria; Pseudomonadati; Pseudomonadota; Alphaproteobacteria;
OC Hyphomicrobiales; Chelatococcaceae; Chelatococcus.
OX NCBI_TaxID=1494448 {ECO:0000313|EMBL:GGC75394.1, ECO:0000313|Proteomes:UP000637002};
RN [1] {ECO:0000313|EMBL:GGC75394.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CGMCC 1.12919 {ECO:0000313|EMBL:GGC75394.1};
RX PubMed=25193709;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Walter F., Albersmeier A., Kalinowski J., Ruckert C.;
RT "Complete genome sequence of Corynebacterium casei LMG S-19264T (=DSM
RT 44701T), isolated from a smear-ripened cheese.";
RL Int. J. Syst. Evol. Microbiol. 189:76-77(2014).
RN [2] {ECO:0000313|EMBL:GGC75394.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CGMCC 1.12919 {ECO:0000313|EMBL:GGC75394.1};
RA Sun Q., Zhou Y.;
RL Submitted (SEP-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Translation factor necessary for the incorporation of
CC selenocysteine into proteins. It probably replaces EF-Tu for the
CC insertion of selenocysteine directed by the UGA codon. SelB binds GTP
CC and GDP. {ECO:0000256|ARBA:ARBA00025526}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GGC75394.1}.
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DR EMBL; BMGG01000006; GGC75394.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A916UKV3; -.
DR Proteomes; UP000637002; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0004020; F:adenylylsulfate kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:InterPro.
DR GO; GO:0001514; P:selenocysteine incorporation; IEA:InterPro.
DR CDD; cd04171; SelB; 1.
DR CDD; cd03696; SelB_II; 1.
DR CDD; cd15491; selB_III; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 3.
DR InterPro; IPR057335; Beta-barrel_SelB.
DR InterPro; IPR050055; EF-Tu_GTPase.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR015190; Elong_fac_SelB-wing-hlx_typ-2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR015191; SelB_WHD4.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR InterPro; IPR004535; Transl_elong_SelB.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR00475; selB; 1.
DR PANTHER; PTHR43721; ELONGATION FACTOR TU-RELATED; 1.
DR PANTHER; PTHR43721:SF9; GTP-BINDING PROTEIN 1; 1.
DR Pfam; PF25461; Beta-barrel_SelB; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR Pfam; PF09106; WHD_2nd_SelB; 1.
DR Pfam; PF09107; WHD_3rd_SelB; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SUPFAM; SSF50465; EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 3.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000637002}.
FT DOMAIN 1..171
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT REGION 647..690
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 690 AA; 72967 MW; 9B195D0C30822CBC CRC64;
MIIGTAGHID HGKTALVRAL TGVNTDRLKE EKARGISIDL GFAYQPTPDG DVLGFVDVPG
HERFVRTMLA GAAGIDYVLL VVAADDGVMP QTREHLAILE LLGVTRGVVA LTKADLAAPR
QRETVTAEVR AALVGGALAT ADIVPVSTVT GEGIAALGDR LAREAAAFTA RDTAGRFRLA
IDRSFTLRGA GTVVTGTVLS GSVTVGDHLI VSPSGLPVRV RSIHAQNRPA ERGRAGERCA
LNLAGERVTR EAFARGDVVL DPLLHAPAAR IDATLAVLAS EPRPIGQWSP VRLHTAAVEV
GARVVLLGDG AILPGEEAFV QLVLERPVAA AVGDRYVLRD TSARRTIGGG RLVDLRAPAR
RRRTPQRFAQ LAAQATGAPD AALAALLAVA PRVVELDGFG RDRALSDAQL EAALARPGII
RIATGGVRFA LAGADWEALT SGLRGTLAAF HRDNPDLPGI GLERLRLQSE PRLPAPAFAA
VLRGLARTGD VALDGAWVRL AGHEVHLTPA DEAVWREIRP RLGGTARFRP PRVRDIAGLI
GASEAEVRRL LKRVGRMGEA DEVAHDHFFL RATVAELIDI LGRLAAAAGR SGFTAAQFRD
QVDSGRKVAI QILEFFDRHG VTLRRGDLRH IDVHRLDLFR PAGETEAPAI AGGEASPVGR
PDFKSGRGRA PVSGGFDSHS PPPALSDRAR
//
