ID A0A917GT00_9FLAO Unreviewed; 358 AA.
AC A0A917GT00;
DT 22-FEB-2023, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2023, sequence version 1.
DT 28-JAN-2026, entry version 13.
DE RecName: Full=Peptide chain release factor 1 {ECO:0000256|HAMAP-Rule:MF_00093, ECO:0000256|NCBIfam:TIGR00019};
DE Short=RF-1 {ECO:0000256|HAMAP-Rule:MF_00093};
GN Name=prfA {ECO:0000256|HAMAP-Rule:MF_00093,
GN ECO:0000313|EMBL:GGG55487.1};
GN ORFNames=GCM10010976_27940 {ECO:0000313|EMBL:GGG55487.1};
OS Bizionia arctica.
OC Bacteria; Pseudomonadati; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Bizionia.
OX NCBI_TaxID=1495645 {ECO:0000313|EMBL:GGG55487.1, ECO:0000313|Proteomes:UP000625976};
RN [1] {ECO:0000313|EMBL:GGG55487.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CGMCC 1.12751 {ECO:0000313|EMBL:GGG55487.1};
RX PubMed=25193709;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Walter F., Albersmeier A., Kalinowski J., Ruckert C.;
RT "Complete genome sequence of Corynebacterium casei LMG S-19264T (=DSM
RT 44701T), isolated from a smear-ripened cheese.";
RL Int. J. Syst. Evol. Microbiol. 189:76-77(2014).
RN [2] {ECO:0000313|EMBL:GGG55487.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CGMCC 1.12751 {ECO:0000313|EMBL:GGG55487.1};
RA Sun Q., Zhou Y.;
RL Submitted (SEP-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Peptide chain release factor 1 directs the termination of
CC translation in response to the peptide chain termination codons UAG and
CC UAA. {ECO:0000256|ARBA:ARBA00002986, ECO:0000256|HAMAP-Rule:MF_00093}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00093}.
CC -!- PTM: Methylated by PrmC. Methylation increases the termination
CC efficiency of RF1. {ECO:0000256|HAMAP-Rule:MF_00093}.
CC -!- SIMILARITY: Belongs to the prokaryotic/mitochondrial release factor
CC family. {ECO:0000256|ARBA:ARBA00010835, ECO:0000256|HAMAP-
CC Rule:MF_00093}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GGG55487.1}.
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DR EMBL; BMFQ01000003; GGG55487.1; -; Genomic_DNA.
DR RefSeq; WP_188465920.1; NZ_BMFQ01000003.1.
DR AlphaFoldDB; A0A917GT00; -.
DR Proteomes; UP000625976; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0016149; F:translation release factor activity, codon specific; IEA:UniProtKB-UniRule.
DR FunFam; 3.30.160.20:FF:000004; Peptide chain release factor 1; 1.
DR FunFam; 3.30.70.1660:FF:000002; Peptide chain release factor 1; 1.
DR Gene3D; 3.30.160.20; -; 1.
DR Gene3D; 3.30.70.1660; -; 1.
DR Gene3D; 6.10.140.1950; -; 1.
DR HAMAP; MF_00093; Rel_fac_1; 1.
DR InterPro; IPR005139; PCRF.
DR InterPro; IPR000352; Pep_chain_release_fac_I.
DR InterPro; IPR045853; Pep_chain_release_fac_I_sf.
DR InterPro; IPR050057; Prokaryotic/Mito_RF.
DR InterPro; IPR004373; RF-1.
DR NCBIfam; TIGR00019; prfA; 1.
DR NCBIfam; NF001859; PRK00591.1; 1.
DR PANTHER; PTHR43804; LD18447P; 1.
DR PANTHER; PTHR43804:SF7; LD18447P; 1.
DR Pfam; PF03462; PCRF; 1.
DR Pfam; PF00472; RF-1; 1.
DR SMART; SM00937; PCRF; 1.
DR SUPFAM; SSF75620; Release factor; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00093};
KW Methylation {ECO:0000256|ARBA:ARBA00022481, ECO:0000256|HAMAP-
KW Rule:MF_00093};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917, ECO:0000256|HAMAP-
KW Rule:MF_00093}; Reference proteome {ECO:0000313|Proteomes:UP000625976}.
FT DOMAIN 62..177
FT /note="Peptide chain release factor"
FT /evidence="ECO:0000259|SMART:SM00937"
FT COILED 41..71
FT /evidence="ECO:0000256|SAM:Coils"
FT MOD_RES 233
FT /note="N5-methylglutamine"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00093"
SQ SEQUENCE 358 AA; 40528 MW; 535C63F7C4FA122D CRC64;
MLDKLQIVKQ RFDEVSDLII QPDIMTDQKR YVELNKEYKD LRLLMDKREE YIELTENLKE
AEEILADGSD QEMVDMAKMQ YDEAKEGIPK LEDAIKVLLI PKDPEDVKNA VVELRAGTGG
DEASIFAGDL FRMYSKYCES KGWKVDTVDY SEGTNGGFKE IQFEVTGDNV YGTLKFEAGV
HRVQRVPQTE TQGRVHTSAA TVMVFPEAEE FDVEINPKEV RVDFFCSSGP GGQSVNTTYS
AVRLTHIPTG LVAQCQDQKS QHKNKEKAFK VLRSRLYEME LAKKNAEDAL KRGSMVSSGD
RSAKIRTYNY SQGRVTDHRI GLTLYDLGNI VNGDIQRIID ELQLAENTEK LKANTDVI
//
