ID A0A917UUX4_9BACI Unreviewed; 396 AA.
AC A0A917UUX4;
DT 22-FEB-2023, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2023, sequence version 1.
DT 02-APR-2025, entry version 11.
DE SubName: Full=Nucleoside transporter {ECO:0000313|EMBL:GGJ88110.1};
GN Name=nupC {ECO:0000313|EMBL:GGJ88110.1};
GN ORFNames=GCM10007063_08270 {ECO:0000313|EMBL:GGJ88110.1};
OS Lentibacillus kapialis.
OC Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae;
OC Lentibacillus.
OX NCBI_TaxID=340214 {ECO:0000313|EMBL:GGJ88110.1, ECO:0000313|Proteomes:UP000658382};
RN [1] {ECO:0000313|EMBL:GGJ88110.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=JCM 12580 {ECO:0000313|EMBL:GGJ88110.1};
RX PubMed=30832757;
RA Wu L., Ma J.;
RT "The Global Catalogue of Microorganisms (GCM) 10K type strain sequencing
RT project: providing services to taxonomists for standard genome sequencing
RT and annotation.";
RL Int. J. Syst. Evol. Microbiol. 69:895-898(2019).
RN [2] {ECO:0000313|EMBL:GGJ88110.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=JCM 12580 {ECO:0000313|EMBL:GGJ88110.1};
RA Sun Q., Ohkuma M.;
RL Submitted (SEP-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
CC -!- SIMILARITY: Belongs to the concentrative nucleoside transporter (CNT)
CC (TC 2.A.41) family. {ECO:0000256|ARBA:ARBA00009033}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GGJ88110.1}.
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DR EMBL; BMNQ01000006; GGJ88110.1; -; Genomic_DNA.
DR RefSeq; WP_188631810.1; NZ_BMNQ01000006.1.
DR Proteomes; UP000658382; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005337; F:nucleoside transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0015293; F:symporter activity; IEA:TreeGrafter.
DR InterPro; IPR008276; C_nuclsd_transpt.
DR InterPro; IPR011657; CNT_C_dom.
DR InterPro; IPR002668; CNT_N_dom.
DR InterPro; IPR011642; Gate_dom.
DR PANTHER; PTHR10590:SF23; NUPC_NUPG FAMILY NUCLEOSIDE CNT TRANSPORTER; 1.
DR PANTHER; PTHR10590; SODIUM/NUCLEOSIDE COTRANSPORTER; 1.
DR Pfam; PF07670; Gate; 1.
DR Pfam; PF07662; Nucleos_tra2_C; 1.
DR Pfam; PF01773; Nucleos_tra2_N; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000658382};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 29..47
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 90..111
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 166..186
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 193..213
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 249..271
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 283..300
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 336..356
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 377..395
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 9..80
FT /note="Concentrative nucleoside transporter N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01773"
FT DOMAIN 91..189
FT /note="Nucleoside transporter/FeoB GTPase Gate"
FT /evidence="ECO:0000259|Pfam:PF07670"
FT DOMAIN 193..393
FT /note="Concentrative nucleoside transporter C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07662"
SQ SEQUENCE 396 AA; 42165 MW; FF88C6CE66C1CAFF CRC64;
MDILFGIIAI AVVLGLAYLM SNDKKNINYR GIIVMLLAQL VITWFMFNTQ IGSAVIKGIS
AGFNKLIEFG KEGINFVVGG IQIAEGGSVF FFNVLLLIIF FATLLSVLTY LRILPPIIKY
LGGLLSKVTG LPRVESFNAV NSIFFGQSEA LLAIKTQFHH LDNNRLYIVS ASAMGSVSAS
IVGAYLQILP PEYVLAALPL NMFSALILAS IIAPVNIPKE EDQVDVQEVS HDKSIFEAMS
NGALDGGKIA LIVAAMLIAF IASLELVNWL IQLVFAGLTL QDILGYIIAP IGILMGISPG
EVIEAGGVMG TKIVTNEFVA MLEFEQKMGG LSEKTIGIVS VFLTSFANFS SIGIIAGTVQ
GIDSKKAVQV SGFGMKLLIG ATFASILSAT IAGLFL
//
