ID A0A919R0L1_9ACTN Unreviewed; 603 AA.
AC A0A919R0L1;
DT 22-FEB-2023, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2023, sequence version 1.
DT 28-JAN-2026, entry version 14.
DE SubName: Full=Translation elongation factor {ECO:0000313|EMBL:GII77163.1};
GN Name=selB {ECO:0000313|EMBL:GII77163.1};
GN ORFNames=Sru01_21450 {ECO:0000313|EMBL:GII77163.1};
OS Sphaerisporangium rufum.
OC Bacteria; Bacillati; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Streptosporangiaceae; Sphaerisporangium.
OX NCBI_TaxID=1381558 {ECO:0000313|EMBL:GII77163.1, ECO:0000313|Proteomes:UP000655287};
RN [1] {ECO:0000313|EMBL:GII77163.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NBRC 109079 {ECO:0000313|EMBL:GII77163.1};
RA Komaki H., Tamura T.;
RT "Whole genome shotgun sequence of Sphaerisporangium rufum NBRC 109079.";
RL Submitted (JAN-2021) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GII77163.1}.
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DR EMBL; BOOU01000032; GII77163.1; -; Genomic_DNA.
DR RefSeq; WP_203984026.1; NZ_BOOU01000032.1.
DR AlphaFoldDB; A0A919R0L1; -.
DR Proteomes; UP000655287; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:TreeGrafter.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0035368; F:selenocysteine insertion sequence binding; IEA:TreeGrafter.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0000049; F:tRNA binding; IEA:TreeGrafter.
DR GO; GO:0001514; P:selenocysteine incorporation; IEA:InterPro.
DR GO; GO:0016259; P:selenocysteine metabolic process; IEA:TreeGrafter.
DR CDD; cd04171; SelB; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR057335; Beta-barrel_SelB.
DR InterPro; IPR050543; eIF2G.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR015191; SelB_WHD4.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR42854; EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 3 FAMILY MEMBER; 1.
DR PANTHER; PTHR42854:SF3; EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 3-RELATED; 1.
DR Pfam; PF25461; Beta-barrel_SelB; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF09107; WHD_3rd_SelB; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Elongation factor {ECO:0000313|EMBL:GII77163.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000655287}.
FT DOMAIN 1..167
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT REGION 265..289
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 603 AA; 61982 MW; 75142AE5E1622BF5 CRC64;
MHVIATAGHV DHGKSTLVRA LTGMEPDRLA EERRRGLTIE LGYAWTTLPS GARLALVDVP
GHERFLSTML AGAGPVPAAL LVVAADEGWM PQSEEHLLAL EALGVRHVLL AVTRSDLADP
GPATRQALAR LAAGGLPGVP AVAVSGRTGT GLAELTAELD RLAARLPGAD PAAPARLWVD
RVFTVRGSGT VVTGTLPAGR IRAGDELSLD GTPVRVRGLQ TLKEQAESVT GVARVAVNLR
GAFTRGTALV TPGAWTGTDL VDVRLTAPGP RGDGGTAPPG GRPGPAAGGD AFALPAEVTA
HIGSAAVTCR VRPLGAGTAR LRLARPLPLH VGDVLVLRDP GRPRELPSVV AGAAVLDVRP
PALRRRGAAR ARAAELAAAP GAAALLRTHR FLPAAELAAM GVKPPGPPVA GDWHADPELW
QALPGRLAAA VGEYAAHDPM EPGMPVEAAR RALGLPDRRL VAALIRPPLT LAAGRITTGG
ASGLPAPVAA AVDRLRAELA GAPFRAPEAD RLAALGLGRK EIAAAVRAGA LLRIAEGVVL
LPGADRRAAA LLAGLPQPFT VSQARQALDT SRRVAVPLLE HLERARLTTR TDDGRHRCRP
VGA
//
