ID A0A920C9X8_9BACL Unreviewed; 297 AA.
AC A0A920C9X8;
DT 22-FEB-2023, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2023, sequence version 1.
DT 05-FEB-2025, entry version 9.
DE SubName: Full=Dihydrodipicolinate synthase family protein {ECO:0000313|EMBL:GIO29589.1};
GN Name=dapA_1 {ECO:0000313|EMBL:GIO29589.1};
GN ORFNames=J2TS6_07300 {ECO:0000313|EMBL:GIO29589.1};
OS Paenibacillus albilobatus.
OC Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
OC Paenibacillus.
OX NCBI_TaxID=2716884 {ECO:0000313|EMBL:GIO29589.1, ECO:0000313|Proteomes:UP000679779};
RN [1] {ECO:0000313|EMBL:GIO29589.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=J2TS6 {ECO:0000313|EMBL:GIO29589.1};
RA Okamoto M., Kumagai M., Kanamori H., Takamatsu D.;
RT "Antimicrobial resistance genes in bacteria isolated from Japanese honey,
RT and their potential for conferring macrolide and lincosamide resistance in
RT the American foulbrood pathogen Paenibacillus larvae.";
RL Submitted (MAR-2021) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the DapA family.
CC {ECO:0000256|PIRNR:PIRNR001365}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GIO29589.1}.
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DR EMBL; BORQ01000001; GIO29589.1; -; Genomic_DNA.
DR Proteomes; UP000679779; Unassembled WGS sequence.
DR GO; GO:0008840; F:4-hydroxy-tetrahydrodipicolinate synthase activity; IEA:TreeGrafter.
DR CDD; cd00408; DHDPS-like; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR002220; DapA-like.
DR PANTHER; PTHR12128; DIHYDRODIPICOLINATE SYNTHASE; 1.
DR PANTHER; PTHR12128:SF72; DIHYDRODIPICOLINATE SYNTHASE; 1.
DR Pfam; PF00701; DHDPS; 1.
DR PIRSF; PIRSF001365; DHDPS; 1.
DR PRINTS; PR00146; DHPICSNTHASE.
DR SMART; SM01130; DHDPS; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|PIRNR:PIRNR001365};
KW Reference proteome {ECO:0000313|Proteomes:UP000679779}.
FT ACT_SITE 134
FT /note="Proton donor/acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
FT ACT_SITE 162
FT /note="Schiff-base intermediate with substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
FT BINDING 202
FT /ligand="pyruvate"
FT /ligand_id="ChEBI:CHEBI:15361"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-2"
SQ SEQUENCE 297 AA; 32831 MW; 9BE6B1A2239E3C08 CRC64;
MSKFPGIYVA TVTPFTASYE VDFNRLKEHV DWLIQKGVDG IIPTGSLGEY ATLTSEERAQ
VITATIDAAA GRVPVVIGGA APSTKQVVEL IQFSKEKGAE GVMALPPINY KPTEDEVVAH
YEAVSNAGLP VIVYNNPYDY PVDLTPRILQ KLSKFENIVA VKEFSGDVRR VYDILRETDL
EVMIGVDDLA LEGALAGATG WIAGFANAFP RESITVFNMT RTGRVDEALE LYRYLLPLFH
FDANPRLVQA IKYVMDFVGQ PAGPSRPPRL PLPEEDRLAV QEAYKYAVNR PIRIVQE
//
