ID A0A927JDJ6_9ACTN Unreviewed; 403 AA.
AC A0A927JDJ6;
DT 22-FEB-2023, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2023, sequence version 1.
DT 18-JUN-2025, entry version 13.
DE RecName: Full=DNA polymerase III subunit delta' {ECO:0000256|ARBA:ARBA00014363};
DE EC=2.7.7.7 {ECO:0000256|ARBA:ARBA00012417};
GN ORFNames=HT102_12315 {ECO:0000313|EMBL:MBD8507269.1};
OS Lolliginicoccus lacisalsi.
OC Bacteria; Bacillati; Actinomycetota; Actinomycetes; Mycobacteriales;
OC Hoyosellaceae; Lolliginicoccus.
OX NCBI_TaxID=2742202 {ECO:0000313|EMBL:MBD8507269.1, ECO:0000313|Proteomes:UP000642993};
RN [1] {ECO:0000313|EMBL:MBD8507269.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=G463 {ECO:0000313|EMBL:MBD8507269.1};
RA Yang Q., Guo P.Y., Liu S.W., Li F.N., Sun C.H.;
RT "Hoyosella lacisalsi sp. nov., a halotolerant actinobacterium isolated from
RT soil of Lake Gudzhirganskoe.";
RL Submitted (SEP-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) +
CC diphosphate; Xref=Rhea:RHEA:22508, Rhea:RHEA-COMP:17339, Rhea:RHEA-
CC COMP:17340, ChEBI:CHEBI:33019, ChEBI:CHEBI:61560, ChEBI:CHEBI:173112;
CC EC=2.7.7.7; Evidence={ECO:0000256|ARBA:ARBA00049244};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:MBD8507269.1}.
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DR EMBL; JACYWE010000007; MBD8507269.1; -; Genomic_DNA.
DR RefSeq; WP_192039716.1; NZ_JACYWE010000007.1.
DR Proteomes; UP000642993; Unassembled WGS sequence.
DR GO; GO:0009360; C:DNA polymerase III complex; IEA:InterPro.
DR GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0006261; P:DNA-templated DNA replication; IEA:TreeGrafter.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR004622; DNA_pol_HolB.
DR InterPro; IPR015199; DNA_pol_III_delta_C.
DR InterPro; IPR050238; DNA_Rep/Repair_Clamp_Loader.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR00678; holB; 1.
DR NCBIfam; NF005926; PRK07940.1; 1.
DR PANTHER; PTHR11669:SF8; DNA POLYMERASE III SUBUNIT DELTA; 1.
DR PANTHER; PTHR11669; REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT; 1.
DR Pfam; PF13177; DNA_pol3_delta2; 1.
DR Pfam; PF09115; DNApol3-delta_C; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00022932};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695,
KW ECO:0000313|EMBL:MBD8507269.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000642993};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:MBD8507269.1}.
FT DOMAIN 40..183
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
SQ SEQUENCE 403 AA; 42560 MW; 4CAADB9FB2A07B0B CRC64;
MAAVFDKLLG QDHAIRELLA ASTDARRSTR GSASIEHSAM THAWLFTGPP GSGRSIAALC
LAAALQCTSP DGPGCGHCAG CTSTLGGNHP DVRRIIPEGL SIATADMRAI VRTAARRPSV
GAWHVIIIED ADRLTEGAAN ALLKMVEEPP SHTVFMLCAP SPDPHDIAVT LRSRCRHITL
TTPSTTAIAH ALEARDHLDA ETAHWAAAIS AGHIGRARRL ATDEQARSRR ATVLAMPPTL
DRPAAAINAA DTLLATATED AKTLTAEIDT RETEELRTAL GAGGTGKGAA GALRGSAGAL
KDLERKQKSR ATRAIRDALD RALIDLAGYY RDALLASLGT TASPIHPDKS DDITQIARST
RPETLLNCID AILHCRDTLA TNTKPELAIT AMLTTISEHM RRG
//
