ID A0A927LXF0_9BACL Unreviewed; 539 AA.
AC A0A927LXF0;
DT 22-FEB-2023, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2023, sequence version 1.
DT 18-JUN-2025, entry version 13.
DE SubName: Full=NADH-quinone oxidoreductase subunit M {ECO:0000313|EMBL:MBE1447304.1};
GN ORFNames=GGC63_006831 {ECO:0000313|EMBL:MBE1447304.1};
OS Paenibacillus sp. OAS669.
OC Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
OC Paenibacillus.
OX NCBI_TaxID=2663821 {ECO:0000313|EMBL:MBE1447304.1, ECO:0000313|Proteomes:UP000608782};
RN [1] {ECO:0000313|EMBL:MBE1447304.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=OAS669 {ECO:0000313|EMBL:MBE1447304.1};
RA Northen T.;
RT "Enriched cells from switchgrass and soil in EcoFAB chamber, Walnut Creek,
RT California, United States.";
RL Submitted (OCT-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|RuleBase:RU000320}; Multi-pass membrane protein
CC {ECO:0000256|RuleBase:RU000320}.
CC -!- SIMILARITY: Belongs to the complex I subunit 4 family.
CC {ECO:0000256|ARBA:ARBA00009025}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:MBE1447304.1}.
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DR EMBL; JADBDR010000027; MBE1447304.1; -; Genomic_DNA.
DR RefSeq; WP_192705845.1; NZ_JADBDR010000027.1.
DR Proteomes; UP000608782; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
DR GO; GO:0048039; F:ubiquinone binding; IEA:TreeGrafter.
DR GO; GO:0042773; P:ATP synthesis coupled electron transport; IEA:InterPro.
DR GO; GO:0015990; P:electron transport coupled proton transport; IEA:TreeGrafter.
DR InterPro; IPR000260; NADH4_N.
DR InterPro; IPR010227; NADH_Q_OxRdtase_chainM/4.
DR InterPro; IPR003918; NADH_UbQ_OxRdtase.
DR InterPro; IPR001750; ND/Mrp_TM.
DR NCBIfam; TIGR01972; NDH_I_M; 1.
DR PANTHER; PTHR43507; NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 4; 1.
DR PANTHER; PTHR43507:SF1; NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 4; 1.
DR Pfam; PF01059; Oxidored_q5_N; 1.
DR Pfam; PF00361; Proton_antipo_M; 1.
DR PRINTS; PR01437; NUOXDRDTASE4.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius}; NAD {ECO:0000256|ARBA:ARBA00023027};
KW Reference proteome {ECO:0000313|Proteomes:UP000608782};
KW Translocase {ECO:0000256|ARBA:ARBA00022967};
KW Transmembrane {ECO:0000256|RuleBase:RU000320, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..24
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 36..55
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 101..123
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 130..147
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 153..173
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 185..207
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 254..274
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 295..313
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 319..340
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 347..369
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 375..396
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 416..438
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 453..476
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 496..515
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 84..136
FT /note="NADH:ubiquinone oxidoreductase chain 4 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01059"
FT DOMAIN 147..464
FT /note="NADH:quinone oxidoreductase/Mrp antiporter
FT transmembrane"
FT /evidence="ECO:0000259|Pfam:PF00361"
SQ SEQUENCE 539 AA; 59110 MW; E476E298959CE94C CRC64;
MSDSMHLLSL IAFSPLLGVL VLLFMPAHKG QWIKTVAIVT TLIPLVLSAW LYSAFNHQLE
GMQFKEELGW IQVPLNHEAQ GLNQMTSFFF QFKYIMAVDG LSLPLVFLTA LIGTMAALAS
VYIKKRWKSY FIFYLLLETG MFGVFMAQDL FLFFVFFEVT LIPVFFLIGI WGYMERERAA
NKFLIYNGIG SAIMLIAFII LICTAGFGQV SNDSGNSIFY SGDLSVITSH LFQSEAAYVN
QSDYPFYLSD TMKWVLFIML LVAFGIKLPI FPFHTWMLRV HTEAPPSIVM IHSGILLKMG
AYGLIRFGVL LFPQQAVQWA TVLAILGVIN ILYGAILAFV QKDFKLVLAY SSISHMGIVL
LGIAAFNTIG LEGAVFQLVS HGLISALLFL LVGAIYERTQ TTMLDQLGGL AKNVPFISGI
LLVAGMASLG LPGLSGFISE FLAFAGLFQT AKVITVIGTI GVILTAVYVL RGVLAITYGP
PRIQGDGMKD ARLMEAIPMV ALVAFVVVLG IYPAVLSGPL HQTVSGFDQF IQTVVKIGG
//
