ID   A0A928VU93_9CYAN        Unreviewed;       457 AA.
AC   A0A928VU93;
DT   22-FEB-2023, integrated into UniProtKB/TrEMBL.
DT   22-FEB-2023, sequence version 1.
DT   18-JUN-2025, entry version 10.
DE   RecName: Full=Proton extrusion protein PxcA {ECO:0000256|HAMAP-Rule:MF_01308};
GN   Name=pxcA {ECO:0000256|HAMAP-Rule:MF_01308,
GN   ECO:0000313|EMBL:MBE9040362.1};
GN   ORFNames=IQ235_06095 {ECO:0000313|EMBL:MBE9040362.1};
OS   Zarconia navalis LEGE 11467.
OC   Bacteria; Bacillati; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC   Oscillatoriales; Oscillatoriales incertae sedis; Zarconia;
OC   Zarconia navalis.
OX   NCBI_TaxID=1828826 {ECO:0000313|EMBL:MBE9040362.1, ECO:0000313|Proteomes:UP000621799};
RN   [1] {ECO:0000313|EMBL:MBE9040362.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=LEGE 11467 {ECO:0000313|EMBL:MBE9040362.1};
RA   Castelo-Branco R., Eusebio N., Adriana R., Vieira A.,
RA   Brugerolle De Fraissinette N., Rezende De Castro R., Schneider M.P.,
RA   Vasconcelos V., Leao P.N.;
RL   Submitted (OCT-2020) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for H(+) efflux immediately after light irradiation
CC       to form a rapid H(+) concentration gradient across the thylakoid
CC       membranes. Together with PxcL, contributes to transient H(+) uptake
CC       following dark to light transition. {ECO:0000256|HAMAP-Rule:MF_01308}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000256|HAMAP-
CC       Rule:MF_01308}; Multi-pass membrane protein {ECO:0000256|HAMAP-
CC       Rule:MF_01308}. Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass
CC       membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the CemA family. {ECO:0000256|HAMAP-
CC       Rule:MF_01308}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:MBE9040362.1}.
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DR   EMBL; JADEXN010000077; MBE9040362.1; -; Genomic_DNA.
DR   RefSeq; WP_264320611.1; NZ_JADEXN010000077.1.
DR   Proteomes; UP000621799; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015078; F:proton transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01308; CemA_PxcA; 1.
DR   InterPro; IPR004282; CemA.
DR   NCBIfam; NF002703; PRK02507.1-1; 1.
DR   PANTHER; PTHR33650:SF2; CHLOROPLAST ENVELOPE MEMBRANE PROTEIN; 1.
DR   PANTHER; PTHR33650; CHLOROPLAST ENVELOPE MEMBRANE PROTEIN-RELATED; 1.
DR   Pfam; PF03040; CemA; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane {ECO:0000256|HAMAP-Rule:MF_01308};
KW   Cell membrane {ECO:0000256|HAMAP-Rule:MF_01308};
KW   Hydrogen ion transport {ECO:0000256|ARBA:ARBA00022781, ECO:0000256|HAMAP-
KW   Rule:MF_01308};
KW   Ion transport {ECO:0000256|ARBA:ARBA00023065, ECO:0000256|HAMAP-
KW   Rule:MF_01308};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|HAMAP-Rule:MF_01308};
KW   Reference proteome {ECO:0000313|Proteomes:UP000621799};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|HAMAP-
KW   Rule:MF_01308};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|HAMAP-
KW   Rule:MF_01308};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|HAMAP-Rule:MF_01308}.
FT   REGION          139..179
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        148..157
FT                   /note="Low complexity"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   457 AA;  52768 MW;  BD3336F13AC1C0BB CRC64;
     MKASIFSPVQ KAVGWVKQRY AQTPDRALEA AYRSAIAIEA IENEYFSGEK IQFQRTNLSS
     LELEAIQKEL KTNLGIIRQR IAEFNSSRSI LSLIIQTTTE PAPLQSVDRA NHQYLPEEKE
     RFTQNLKKLK IIDSVVAKYR QSPPQPPSSI SRSQTQRALT TPKPNENRSS DPSLPELFQD
     RIDRPSDVKP VSKRPSVSVL PRSILRTIDR LKRELDPQAE NEVVEEFRYH KNKTVLALKF
     ILLLILIPLL THQLSKNFVI SPIYEHFFAE KSAVFLNHDF EEEAFMDLNR FEERLKFEIL
     IGQTPKLSEE EMEEQVEEKA SEIAMEYHIR SDNAIENVFS DLMSLGAFCL VIFFSKREIA
     VLKSFIDDVV YGLSDSAKAF IIILFTDIFV GYHSPHGWEI ILEGLAHHFG IPESRDFNFL
     FIATFPVILD TVMKYWIFRY LNRISPSAVA TYRNMNE
//