ID A0A928W840_9CYAN Unreviewed; 614 AA.
AC A0A928W840;
DT 22-FEB-2023, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2023, sequence version 1.
DT 05-FEB-2025, entry version 7.
DE RecName: Full=protein-glutamate O-methyltransferase {ECO:0000256|ARBA:ARBA00012534};
DE EC=2.1.1.80 {ECO:0000256|ARBA:ARBA00012534};
GN ORFNames=IQ255_19555 {ECO:0000313|EMBL:MBE9046578.1};
OS Pleurocapsales cyanobacterium LEGE 10410.
OC Bacteria; Bacillati; Cyanobacteriota; Cyanophyceae; Pleurocapsales.
OX NCBI_TaxID=1828828 {ECO:0000313|EMBL:MBE9046578.1, ECO:0000313|Proteomes:UP000651301};
RN [1] {ECO:0000313|EMBL:MBE9046578.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=LEGE 10410 {ECO:0000313|EMBL:MBE9046578.1};
RA Castelo-Branco R., Eusebio N., Adriana R., Vieira A.,
RA Brugerolle De Fraissinette N., Rezende De Castro R., Schneider M.P.,
RA Vasconcelos V., Leao P.N.;
RL Submitted (OCT-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=L-glutamyl-[protein] + S-adenosyl-L-methionine = [protein]-L-
CC glutamate 5-O-methyl ester + S-adenosyl-L-homocysteine;
CC Xref=Rhea:RHEA:24452, Rhea:RHEA-COMP:10208, Rhea:RHEA-COMP:10311,
CC ChEBI:CHEBI:29973, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789,
CC ChEBI:CHEBI:82795; EC=2.1.1.80;
CC Evidence={ECO:0000256|ARBA:ARBA00001541};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:MBE9046578.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JADEXJ010000098; MBE9046578.1; -; Genomic_DNA.
DR Proteomes; UP000651301; Unassembled WGS sequence.
DR GO; GO:0008757; F:S-adenosylmethionine-dependent methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 1.10.155.10; Chemotaxis receptor methyltransferase CheR, N-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR050903; Bact_Chemotaxis_MeTrfase.
DR InterPro; IPR022642; CheR_C.
DR InterPro; IPR000780; CheR_MeTrfase.
DR InterPro; IPR022641; CheR_N.
DR InterPro; IPR036804; CheR_N_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR24422; CHEMOTAXIS PROTEIN METHYLTRANSFERASE; 1.
DR PANTHER; PTHR24422:SF10; CHEMOTAXIS PROTEIN METHYLTRANSFERASE 2; 1.
DR Pfam; PF01739; CheR; 1.
DR Pfam; PF03705; CheR_N; 1.
DR Pfam; PF00989; PAS; 1.
DR PRINTS; PR00996; CHERMTFRASE.
DR SMART; SM00138; MeTrc; 1.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF47757; Chemotaxis receptor methyltransferase CheR, N-terminal domain; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF57997; Tropomyosin; 1.
DR PROSITE; PS50123; CHER; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000651301};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 1..249
FT /note="CheR-type methyltransferase"
FT /evidence="ECO:0000259|PROSITE:PS50123"
FT DOMAIN 499..547
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT REGION 424..463
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 614 AA; 71100 MW; CE663CCD960078A2 CRC64;
MNTNDENTVF ESLLEFLRQE RGFDFTGYKR SSLVRRVRKQ MQAHDIEDFE TYLDYLQVHP
EEFLPLFDTI LINVTGFFRD RPAWNYLREQ IVDRVVRESG KAQIRVWSAG CSSGEEAYTL
AMVFAEAIGM ENLRDRLKIY ATDVDEDALN TARHATYSDK DLKSVPDELR EKYCEAVAGK
YVFRSELRRA VIFGRHDLVQ DAPISRLDLL VCRNTLMYFN AEIQTKILNR FHFALKNTGF
LFLGKAEMML THGNIFTPIS LPNRIFRPVP TNNRRDRISY LTNSQNKDRD NSDEKRQQIK
DSAFDAGFNA QLVIDSAGKL QLANMQARVM FGIKQLDLGR LLQDLEISYR PLELRSHIDR
IYSTRQVAII RDVPRYLPEG NTQYLDIYFN LLENGESETL GVSVSFIDVT RYHELQTELQ
RSNQELETAN EELQSSNEEL ETTNEELQST NEELETTNEE LQSTNEELET MNEELQSTNE
ELQTINDELR QRTSDLDRVN AFFNSILASL KAGVVVIDNQ LNILSWNDEA NEMWGLRFDE
VRGQSLFSLD IGLPIEQLRE PIRNCLAEGG DRQELAIDSI NRRGRSFKCR LSINPLMGPN
QERQGVILLM EVIK
//
