ID A0A931D9Y8_9ACTN Unreviewed; 354 AA.
AC A0A931D9Y8;
DT 22-FEB-2023, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2023, sequence version 1.
DT 08-OCT-2025, entry version 9.
DE SubName: Full=Cell wall-associated NlpC family hydrolase {ECO:0000313|EMBL:MBG6087194.1};
GN ORFNames=IW256_001307 {ECO:0000313|EMBL:MBG6087194.1};
OS Actinomadura viridis.
OC Bacteria; Bacillati; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Thermomonosporaceae; Actinomadura.
OX NCBI_TaxID=58110 {ECO:0000313|EMBL:MBG6087194.1, ECO:0000313|Proteomes:UP000614047};
RN [1] {ECO:0000313|EMBL:MBG6087194.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=DSM 43175 {ECO:0000313|EMBL:MBG6087194.1};
RA Klenk H.-P.;
RT "Sequencing the genomes of 1000 actinobacteria strains.";
RL Submitted (NOV-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase C40 family.
CC {ECO:0000256|ARBA:ARBA00007074}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:MBG6087194.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JADOUA010000001; MBG6087194.1; -; Genomic_DNA.
DR RefSeq; WP_197010093.1; NZ_BAABES010000006.1.
DR Proteomes; UP000614047; Unassembled WGS sequence.
DR GO; GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
DR CDD; cd13399; Slt35-like; 1.
DR Gene3D; 1.10.530.10; -; 1.
DR Gene3D; 3.90.1720.10; endopeptidase domain like (from Nostoc punctiforme); 1.
DR InterPro; IPR023346; Lysozyme-like_dom_sf.
DR InterPro; IPR000064; NLP_P60_dom.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR051794; PG_Endopeptidase_C40.
DR InterPro; IPR031304; SLT_2.
DR PANTHER; PTHR47359:SF3; NLP_P60 DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR47359; PEPTIDOGLYCAN DL-ENDOPEPTIDASE CWLO; 1.
DR Pfam; PF00877; NLPC_P60; 1.
DR Pfam; PF13406; SLT_2; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR SUPFAM; SSF53955; Lysozyme-like; 1.
DR PROSITE; PS51935; NLPC_P60; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:MBG6087194.1};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000614047};
KW Thiol protease {ECO:0000256|ARBA:ARBA00022807}.
FT DOMAIN 212..340
FT /note="NlpC/P60"
FT /evidence="ECO:0000259|PROSITE:PS51935"
SQ SEQUENCE 354 AA; 37910 MW; 829D66FC67D39369 CRC64;
MNRRRLLLAA ALGAAAMLFV ALMIVPVLFG ASQFMFGGGG AGGAACVDTS RAGAQPAEAN
DARAIPADYL ALYKQAGKDY GIPWNVLAGI GKVETSHGTS RLPGVSSGEN YAGAGGPMQF
LAATFKAFAV DGDKDGKKDR YDPDDAIPSA ARYLKHNGAP ERMRTALFMY NHSWDYVNLV
LDWAKRYVGG DFTVVQSNGV ECEDNELPAN VSGLVQRIIA FAMAQRGKRY IFGANGPDAW
DCSSIIQGAY RSVGLNIPRT TFQQWPWGVR IDKGKEQPGD LVFFNSGPGT SANNPGHVGM
VIGKGKMIVA SCSTCKPNIG VKPYKRSDWI GTTRPLARPD MQRKVARLVA QPAN
//
