ID A0A931H0N7_9BURK Unreviewed; 591 AA.
AC A0A931H0N7;
DT 22-FEB-2023, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2023, sequence version 1.
DT 28-JAN-2026, entry version 16.
DE RecName: Full=Selenocysteine-specific elongation factor {ECO:0000256|ARBA:ARBA00015953};
DE AltName: Full=SelB translation factor {ECO:0000256|ARBA:ARBA00031615};
GN Name=selB {ECO:0000313|EMBL:MBG9386413.1};
GN ORFNames=I5803_00120 {ECO:0000313|EMBL:MBG9386413.1};
OS Caenimonas aquaedulcis.
OC Bacteria; Pseudomonadati; Pseudomonadota; Betaproteobacteria;
OC Burkholderiales; Comamonadaceae; Caenimonas.
OX NCBI_TaxID=2793270 {ECO:0000313|EMBL:MBG9386413.1, ECO:0000313|Proteomes:UP000651050};
RN [1] {ECO:0000313|EMBL:MBG9386413.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=DR4.4 {ECO:0000313|EMBL:MBG9386413.1};
RA Le V., Ko S.-R., Ahn C.-Y., Oh H.-M.;
RT "Bacterial whole genome sequence for Caenimonas sp. DR4.4.";
RL Submitted (NOV-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Translation factor necessary for the incorporation of
CC selenocysteine into proteins. It probably replaces EF-Tu for the
CC insertion of selenocysteine directed by the UGA codon. SelB binds GTP
CC and GDP. {ECO:0000256|ARBA:ARBA00025526}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:MBG9386413.1}.
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DR EMBL; JADWYS010000001; MBG9386413.1; -; Genomic_DNA.
DR RefSeq; WP_196984403.1; NZ_JADWYS010000001.1.
DR AlphaFoldDB; A0A931H0N7; -.
DR Proteomes; UP000651050; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:TreeGrafter.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0001514; P:selenocysteine incorporation; IEA:InterPro.
DR CDD; cd04171; SelB; 1.
DR CDD; cd03696; SelB_II; 1.
DR CDD; cd15491; selB_III; 1.
DR FunFam; 3.40.50.300:FF:001064; Selenocysteine-specific translation elongation factor; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR057335; Beta-barrel_SelB.
DR InterPro; IPR050055; EF-Tu_GTPase.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR031157; G_TR_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR015191; SelB_WHD4.
DR InterPro; IPR005225; Small_GTP-bd.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR InterPro; IPR004535; Transl_elong_SelB.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR00475; selB; 1.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR43721:SF22; ELONGATION FACTOR TU, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43721; ELONGATION FACTOR TU-RELATED; 1.
DR Pfam; PF25461; Beta-barrel_SelB; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR Pfam; PF09107; WHD_3rd_SelB; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SUPFAM; SSF50465; EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00301; G_TR_1; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Elongation factor {ECO:0000313|EMBL:MBG9386413.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000651050}.
FT DOMAIN 1..172
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT REGION 571..591
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 573..584
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 591 AA; 63295 MW; 70F1146EA5B8951D CRC64;
MIVATAGHID HGKTTLVKAL TGVDTDRLPQ EKARGISIDI GFAYWQTPGG AVVGFVDVPG
HERFVRNMLA GVCGIDYAMV VVAADDGVMP QTREHLNILD LLGIRFGVAV ITKADRVDSA
RLREVADETR GLLQGTSLQD VRVLPVSSVT GAGVDALRDA LAQAAAGFTR NASEGRRMRF
AVDRAFTVAG SGTVVTGTVF DGAVRLGDRL LLSPGGREVR VRGIQKDGVK AERAQAGERC
ALNLAGVELS QVQRGDWVLH ADLHAPTSRL DVELQVLPGE AHALAHRTPV HLHLGTRDVT
ARVTLSHGSS VEPGRRAFAR LIVDQPIAAA RGDRFILRDQ SAQRTLGGGW VLDASPSQRR
LPQEMRVRQM QALAQPTPVD ALRALVACSP GGVDATALTR NFNLAPEAFT QLLKEAGLAA
VGTGAQTLVL TPAAADAKLL RKPVQALPEN PEHVRLWQLA EPVLRRAGFA GVTVAQLSEA
LRAKEFVLRD MLHRKAQAGD TVRVNDDRFY ARATIDEFIR VARTVAQHAP DGRFTAGKFR
DDAGIGRALA VQVLEALDRI GATQRVADVR VMRSPARSPS SESPLQGART P
//
