ID A0A931HXU2_9BACI Unreviewed; 318 AA.
AC A0A931HXU2;
DT 22-FEB-2023, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2023, sequence version 1.
DT 18-JUN-2025, entry version 11.
DE RecName: Full=UV DNA damage endonuclease {ECO:0000256|HAMAP-Rule:MF_00606};
DE Short=UV-endonuclease {ECO:0000256|HAMAP-Rule:MF_00606};
DE Short=UVED {ECO:0000256|HAMAP-Rule:MF_00606};
DE EC=3.-.-.- {ECO:0000256|HAMAP-Rule:MF_00606};
GN Name=uvsE {ECO:0000256|HAMAP-Rule:MF_00606,
GN ECO:0000313|EMBL:MBH0231695.1};
GN ORFNames=H0267_15900 {ECO:0000313|EMBL:MBH0231695.1};
OS Halobacillus yeomjeoni.
OC Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae;
OC Halobacillus.
OX NCBI_TaxID=311194 {ECO:0000313|EMBL:MBH0231695.1, ECO:0000313|Proteomes:UP000614490};
RN [1] {ECO:0000313|EMBL:MBH0231695.1, ECO:0000313|Proteomes:UP000614490}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KCTC 3957 {ECO:0000313|EMBL:MBH0231695.1,
RC ECO:0000313|Proteomes:UP000614490};
RX PubMed=16280505;
RA Yoon J.H., Kang S.J., Lee C.H., Oh H.W., Oh T.K.;
RT "Halobacillus yeomjeoni sp. nov., isolated from a marine solar saltern in
RT Korea.";
RL Int. J. Syst. Evol. Microbiol. 55:2413-2417(2005).
CC -!- FUNCTION: Component in a DNA repair pathway. Removal of UV LIGHT
CC damaged nucleotides. Recognizes pyrimidine dimers and cleave a
CC phosphodiester bond immediately 5' to the lesion.
CC {ECO:0000256|ARBA:ARBA00025029}.
CC -!- FUNCTION: Component in a DNA repair pathway. Removal of UV-light
CC damaged nucleotides. Recognizes pyrimidine dimers and cleave a
CC phosphodiester bond immediately 5' to the lesion. {ECO:0000256|HAMAP-
CC Rule:MF_00606}.
CC -!- SIMILARITY: Belongs to the uve1/UvsE family. {ECO:0000256|HAMAP-
CC Rule:MF_00606}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:MBH0231695.1}.
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DR EMBL; JADZSC010000004; MBH0231695.1; -; Genomic_DNA.
DR RefSeq; WP_197318327.1; NZ_JADZSC010000004.1.
DR Proteomes; UP000614490; Unassembled WGS sequence.
DR GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR GO; GO:0006290; P:pyrimidine dimer repair; IEA:UniProtKB-UniRule.
DR GO; GO:0009411; P:response to UV; IEA:InterPro.
DR Gene3D; 3.20.20.150; Divalent-metal-dependent TIM barrel enzymes; 1.
DR HAMAP; MF_00606; UV_endonuclease; 1.
DR InterPro; IPR004601; UvdE.
DR InterPro; IPR023520; UvdE_bac.
DR InterPro; IPR036237; Xyl_isomerase-like_sf.
DR NCBIfam; TIGR00629; uvde; 1.
DR PANTHER; PTHR31290; UV-DAMAGE ENDONUCLEASE; 1.
DR PANTHER; PTHR31290:SF5; UV-DAMAGE ENDONUCLEASE; 1.
DR Pfam; PF03851; UvdE; 1.
DR SUPFAM; SSF51658; Xylose isomerase-like; 1.
PE 3: Inferred from homology;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763, ECO:0000256|HAMAP-
KW Rule:MF_00606};
KW DNA excision {ECO:0000256|ARBA:ARBA00022769, ECO:0000256|HAMAP-
KW Rule:MF_00606};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204, ECO:0000256|HAMAP-
KW Rule:MF_00606};
KW Endonuclease {ECO:0000256|ARBA:ARBA00022759, ECO:0000256|HAMAP-
KW Rule:MF_00606};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|HAMAP-Rule:MF_00606};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722, ECO:0000256|HAMAP-Rule:MF_00606};
KW Reference proteome {ECO:0000313|Proteomes:UP000614490}.
SQ SEQUENCE 318 AA; 37203 MW; A12B2304E7568FBE CRC64;
MQIRFGYVSH ALSLWEATPA KTLTYSRYKK MSPEERIEKL EYITRTNLLH TLRALHYNIA
HEINLYRFSS SLVPLATHYE VEWDYITPFE DLYKEIGSLV QRHEMRTSFH PNQFTLFTSD
KNHVTQNAVQ DMEYHYALLE AMGLHEESHI NLHVGGAYGN KENALKRFHE NLNTLPGPIK
DQMTLENDDK TYTTSETLEV CEKESIPMMF DYHHFMANNT EEESLTDLLP RFYKTWERLG
MPPKIHISSP KSENAFRSHA SYVDPEFIKP LLKELKRLDV AVDFMIEAKE KDRALLQLID
DLSNIRGYKR VGGATLKI
//
