ID A0A934W7M4_9BURK Unreviewed; 647 AA.
AC A0A934W7M4;
DT 22-FEB-2023, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2023, sequence version 1.
DT 28-JAN-2026, entry version 15.
DE RecName: Full=Selenocysteine-specific elongation factor {ECO:0000256|ARBA:ARBA00015953};
DE AltName: Full=SelB translation factor {ECO:0000256|ARBA:ARBA00031615};
GN Name=selB {ECO:0000313|EMBL:MBK4736555.1};
GN ORFNames=JJB74_18175 {ECO:0000313|EMBL:MBK4736555.1};
OS Noviherbaspirillum pedocola.
OC Bacteria; Pseudomonadati; Pseudomonadota; Betaproteobacteria;
OC Burkholderiales; Oxalobacteraceae; Noviherbaspirillum.
OX NCBI_TaxID=2801341 {ECO:0000313|EMBL:MBK4736555.1, ECO:0000313|Proteomes:UP000622890};
RN [1] {ECO:0000313|EMBL:MBK4736555.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=DKR-6 {ECO:0000313|EMBL:MBK4736555.1};
RA Chaudhary D.K.;
RT "Genome sequence of strain Noviherbaspirillum sp. DKR-6.";
RL Submitted (JAN-2021) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Translation factor necessary for the incorporation of
CC selenocysteine into proteins. It probably replaces EF-Tu for the
CC insertion of selenocysteine directed by the UGA codon. SelB binds GTP
CC and GDP. {ECO:0000256|ARBA:ARBA00025526}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:MBK4736555.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JAEPBG010000008; MBK4736555.1; -; Genomic_DNA.
DR RefSeq; WP_200594120.1; NZ_JAEPBG010000008.1.
DR AlphaFoldDB; A0A934W7M4; -.
DR Proteomes; UP000622890; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0001514; P:selenocysteine incorporation; IEA:InterPro.
DR CDD; cd04171; SelB; 1.
DR CDD; cd15491; selB_III; 1.
DR Gene3D; 1.10.10.2770; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR057335; Beta-barrel_SelB.
DR InterPro; IPR050055; EF-Tu_GTPase.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR015191; SelB_WHD4.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR InterPro; IPR004535; Transl_elong_SelB.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR00475; selB; 1.
DR PANTHER; PTHR43721; ELONGATION FACTOR TU-RELATED; 1.
DR PANTHER; PTHR43721:SF11; SELENOCYSTEINE-SPECIFIC ELONGATION FACTOR; 1.
DR Pfam; PF25461; Beta-barrel_SelB; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR Pfam; PF09107; WHD_3rd_SelB; 1.
DR SUPFAM; SSF50465; EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 2.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Elongation factor {ECO:0000313|EMBL:MBK4736555.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000622890}.
FT DOMAIN 5..180
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
SQ SEQUENCE 647 AA; 68671 MW; 9F99E49E2822F875 CRC64;
MNGGNAHLTL GVIGHVDHGK TSLVRALTGT DTDRLKEEKE RGMSIVLGFA WLGFEEGIVD
VIDVPGHEAF VRTMIAGATG IDAALLVVDA REGIKPQTLE HLAIIELIGV SRGVIAITKS
DLVPGAERDA LLRRLRMRLK GTPLEFAPAV ATSIISGEGI AELKAALRGL LLAHEDAAPS
LARGYLPIDR VFSLPGHGTI VTGTLRAGRI AIGEELELMP SGRRATVRQL EMHGREVNMV
HAGQRVGVNL RHVKPQDVTR GDVLAAPGLL KLGEWLDAEI RVTPDAPAPI ANGQTLRLLF
GATDVAARVR LLGKETLAPG EAGLGQLRTA RPVAAAAGEA FILRRESPAA TLGGGRLLDV
AAGRHRRGDG AVRQRLAVLA RGRGDEALAE RLRGSGIAGM PLPRIAEMLG CDSDAARAAI
DGYARLHGAT VLHLQHHDAL CEALLACLRD FHRREPARAG APLPLCRASL PREVDDKLFK
SILRGLASSG NIAFGNGLAW LPGHDPFAAL DAKARGRAEQ IEAHFLQGGV TPPDVEDYTI
ERASAALFHM LVEQGRILLL TGQLPGQRIA FHREAIEAAK ARIRSAYPAP ARFTVSEARG
LLGSTRKFTV PLLAHLDAAG FTRRNGDIRV LREGLQAGAA ARSGEGA
//
