ID A0A938XNG9_9FIRM Unreviewed; 635 AA.
AC A0A938XNG9;
DT 22-FEB-2023, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2023, sequence version 1.
DT 28-JAN-2026, entry version 15.
DE RecName: Full=Selenocysteine-specific elongation factor {ECO:0000256|ARBA:ARBA00015953};
DE AltName: Full=SelB translation factor {ECO:0000256|ARBA:ARBA00031615};
GN ORFNames=JOC47_000558 {ECO:0000313|EMBL:MBM7555733.1};
OS Halanaerobacter jeridensis.
OC Bacteria; Bacillati; Bacillota; Clostridia; Halanaerobiales;
OC Halobacteroidaceae; Halanaerobacter.
OX NCBI_TaxID=706427 {ECO:0000313|EMBL:MBM7555733.1, ECO:0000313|Proteomes:UP000774000};
RN [1] {ECO:0000313|EMBL:MBM7555733.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=DSM 23230 {ECO:0000313|EMBL:MBM7555733.1};
RA Goeker M.;
RT "Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing the
RT most valuable type-strain genomes for metagenomic binning, comparative
RT biology and taxonomic classification.";
RL Submitted (JAN-2021) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Translation factor necessary for the incorporation of
CC selenocysteine into proteins. It probably replaces EF-Tu for the
CC insertion of selenocysteine directed by the UGA codon. SelB binds GTP
CC and GDP. {ECO:0000256|ARBA:ARBA00025526}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:MBM7555733.1}.
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DR EMBL; JAFBDQ010000002; MBM7555733.1; -; Genomic_DNA.
DR RefSeq; WP_204700453.1; NZ_JAFBDQ010000002.1.
DR AlphaFoldDB; A0A938XNG9; -.
DR Proteomes; UP000774000; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0001514; P:selenocysteine incorporation; IEA:InterPro.
DR CDD; cd04171; SelB; 1.
DR CDD; cd03696; SelB_II; 1.
DR CDD; cd15491; selB_III; 1.
DR Gene3D; 1.10.10.2770; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR057335; Beta-barrel_SelB.
DR InterPro; IPR050055; EF-Tu_GTPase.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR015190; Elong_fac_SelB-wing-hlx_typ-2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR015191; SelB_WHD4.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR InterPro; IPR004535; Transl_elong_SelB.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR00475; selB; 1.
DR PANTHER; PTHR43721:SF22; ELONGATION FACTOR TU, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43721; ELONGATION FACTOR TU-RELATED; 1.
DR Pfam; PF25461; Beta-barrel_SelB; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR Pfam; PF09106; WHD_2nd_SelB; 1.
DR Pfam; PF09107; WHD_3rd_SelB; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SUPFAM; SSF50465; EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 3.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Elongation factor {ECO:0000313|EMBL:MBM7555733.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000774000}.
FT DOMAIN 2..174
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT COILED 440..502
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 635 AA; 71404 MW; 9CB160A21B36DB7E CRC64;
MAENLIIGTA GHVDHGKTTL IGALTGENTD RLEEEQERGL SIDLGFSRLN FDNGLQAGII
DVPGHEKFIK NMLAGAGGVD IGLLVVAADE AIMEQTREHL AILELLNVEQ GVIAVTKSDK
VDSEWLELVI DEIKEFVEDT FLEDAAVIPV SGIEETGIED LKEELGHLMQ QLPDKDKEAN
VYFPIDRVFS IGGHGTVVTG TLMQGQIQLE DELEIYPSQL KARVRGLQVH EKDVEVAQPG
QRIGINLSGV DKDEIERGDV LAAQDSLVKT EYLDARLELI ESAPLVLEHG ERIRLHLGAK
EVIGRVYLLD SEELLPGEEG LVQFRLEDTV VANFKERYVL RRYSPMTTIG GGKILEANPA
QHRKNDEAVI KALQIKEEGT TAERIKLALQ REEDKALTVD DLVTRTSLAQ EQIREELMGL
QSRNEVIELD VGTESSLLHS DDYQQLMEEI IANLKDYHQE YHLRLGMPKE ELRTKLSLAL
TANEYDRLLD DLKEQEVIEE KQAKISLADF AVKLTADEKK IKAEIEEKFA QNKYLPPKLD
GLISSYSDEQ VAEEISNLLI NNGELIKVAH NIYFDYQAVK EAKELLINYL KKNETIDVAQ
FRDLLDSSRK YALPLLEYFD QRGVTKREGD IRRLS
//
