ID A0A940NJ28_9BACI Unreviewed; 397 AA.
AC A0A940NJ28;
DT 22-FEB-2023, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2023, sequence version 1.
DT 02-APR-2025, entry version 10.
DE SubName: Full=NupC/NupG family nucleoside CNT transporter {ECO:0000313|EMBL:MBP0725290.1};
GN ORFNames=J5Y03_08815 {ECO:0000313|EMBL:MBP0725290.1};
OS Gottfriedia endophytica.
OC Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae;
OC Gottfriedia.
OX NCBI_TaxID=2820819 {ECO:0000313|EMBL:MBP0725290.1, ECO:0000313|Proteomes:UP000682134};
RN [1] {ECO:0000313|EMBL:MBP0725290.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=RG28 {ECO:0000313|EMBL:MBP0725290.1};
RA Chhetri G.;
RT "Genome seq and assembly of Bacillus sp.";
RL Submitted (APR-2021) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
CC -!- SIMILARITY: Belongs to the concentrative nucleoside transporter (CNT)
CC (TC 2.A.41) family. {ECO:0000256|ARBA:ARBA00009033}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:MBP0725290.1}.
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DR EMBL; JAGIYQ010000005; MBP0725290.1; -; Genomic_DNA.
DR RefSeq; WP_209405279.1; NZ_JAGIYQ010000005.1.
DR Proteomes; UP000682134; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005337; F:nucleoside transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0015293; F:symporter activity; IEA:TreeGrafter.
DR InterPro; IPR008276; C_nuclsd_transpt.
DR InterPro; IPR011657; CNT_C_dom.
DR InterPro; IPR002668; CNT_N_dom.
DR PANTHER; PTHR10590:SF19; PURINE NUCLEOSIDE TRANSPORT PROTEIN NUPG; 1.
DR PANTHER; PTHR10590; SODIUM/NUCLEOSIDE COTRANSPORTER; 1.
DR Pfam; PF07662; Nucleos_tra2_C; 1.
DR Pfam; PF01773; Nucleos_tra2_N; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000682134};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..22
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 29..47
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 53..78
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 90..116
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 165..186
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 237..262
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 282..305
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 330..355
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 375..396
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 8..80
FT /note="Concentrative nucleoside transporter N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01773"
FT DOMAIN 192..393
FT /note="Concentrative nucleoside transporter C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07662"
SQ SEQUENCE 397 AA; 43584 MW; C94ABA17B68DE1F3 CRC64;
MFFFLNLIGI FVVIGLVFLC SPNKRNVKWR SIIVLAIVEV IITWFMLGTK FGAWTINLIA
SFFSFLVSSA YQGISFAFPS AMSIPHVDFF FAALMPIIFI ITFFDILTYF GILTWIIDKV
GWVISKISGL PKLESFFSIQ MMFLGNTEAL AVIRQQLAVL KENRLLTFGI MGMSSISGSI
IGAYLTMVPA KYVFAAIPLN CLNALLLASM LNPIFVSKEA DIVYIPSKEE KRDFFSTISN
SMIVGINMVI VIVAMVIGYV ALTACLNGIL EFFVKGLTIQ KIFSVIFSPF AYLLGLTGHD
AAYVAQLMGI KLATNEFVAM MDLKGRLNGL APHTVAVATT FLTSFANFST VGMIYGTFSS
ILGGDKSAII GRNVWRLLVS GIAVSLLSAM LVGLFVW
//
