ID A0A941ANZ4_9BACI Unreviewed; 726 AA.
AC A0A941ANZ4;
DT 22-FEB-2023, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2023, sequence version 1.
DT 18-JUN-2025, entry version 8.
DE SubName: Full=HD family phosphohydrolase {ECO:0000313|EMBL:MBP3951296.1};
GN ORFNames=J7W16_09135 {ECO:0000313|EMBL:MBP3951296.1};
OS Halalkalibacter suaedae.
OC Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae;
OC Halalkalibacter.
OX NCBI_TaxID=2822140 {ECO:0000313|EMBL:MBP3951296.1, ECO:0000313|Proteomes:UP000678228};
RN [1] {ECO:0000313|EMBL:MBP3951296.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=YZJH907-2 {ECO:0000313|EMBL:MBP3951296.1};
RA Lei R.F.R.;
RT "Bacillus suaedae sp. nov., isolated from Suaeda aralocaspica.";
RL Submitted (MAR-2021) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:MBP3951296.1}.
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DR EMBL; JAGKSQ010000003; MBP3951296.1; -; Genomic_DNA.
DR RefSeq; WP_210596985.1; NZ_JAGKSQ010000003.1.
DR Proteomes; UP000678228; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00077; HDc; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR006674; HD_domain.
DR InterPro; IPR006675; HDIG_dom.
DR InterPro; IPR011624; Metal-dep_PHydrolase_7TM_extra.
DR InterPro; IPR011621; Metal-dep_PHydrolase_7TM_intra.
DR InterPro; IPR052722; PgpH_phosphodiesterase.
DR NCBIfam; TIGR00277; HDIG; 1.
DR PANTHER; PTHR36442; CYCLIC-DI-AMP PHOSPHODIESTERASE PGPH; 1.
DR PANTHER; PTHR36442:SF1; CYCLIC-DI-AMP PHOSPHODIESTERASE PGPH; 1.
DR Pfam; PF07698; 7TM-7TMR_HD; 1.
DR Pfam; PF07697; 7TMR-HDED; 1.
DR Pfam; PF01966; HD; 1.
DR SMART; SM00471; HDc; 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000678228};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..43
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 287..308
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 320..338
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 344..364
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 394..414
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 426..444
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 456..479
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 508..664
FT /note="HD/PDEase"
FT /evidence="ECO:0000259|SMART:SM00471"
SQ SEQUENCE 726 AA; 81749 MW; E417937FCE770D62 CRC64;
MKRQSPIDQQ KWWRRLRNHP YIRAILFVLI GISLYLMMLG NVIPDTLDVR LSQIADQDIR
SPITIEHKTA TEIRRAEARD AIGPVYEQKK EYAQNQVRKV HDIFDLIIQV NEEVPQIEET
TEGEREEVVL TEEEILEQRL AYVDEVLSPG TSNDLSEETI ITFIEASDSQ LQIARETATN
AVFEIMNQTI SIRDLAESKR EVSNQIAIST VSNELLKAMI EIAQFAIIPN YIYDANATQQ
LRQEAAENVE PVLIREGELL VREGEMITHE IYEQLRVVGL LDDRINVFPY IGLALLVLLI
VLMLSYYLKE AETTVQKNNS HLLMFTIIFL LTVALIKITS LLQIIEIQGL GFIVPVSIGA
MLITLLIHTR VAIFASMMFA VIGSVIFNND TAGTFNFTYG FYILFSSFAG AYFLDRSNRV
SRILSAGLFV AGINIVVVTA LLFLKTVQTE WLEVGMHLGF AFLSGFIAAV LTIGLLPFLE
AGFGILSTTR LIELSNPNHP LLRKILVEAP GTYHHSVVVG NLSEAACESI GVNGLLARVG
SYYHDLGKTK RPHFFIENQM KMGNPHDKIS PQLSRTIIIA HPYDGADLLR EHKMPKEIID
IAEQHHGTTL LKYFYHKANQ DSDHPIPESQ FRYPGPKAKT KVSAIVGIAD SVEAAVRTIQ
KPTPDKIETL VRKIIQDKLE DGQFDESDLT LKELDQVAIS ICETLKGTFH ERIEYPEDVK
GKGEKE
//
