ID A0A942TYJ5_9BACI Unreviewed; 680 AA.
AC A0A942TYJ5;
DT 22-FEB-2023, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2023, sequence version 1.
DT 02-APR-2025, entry version 11.
DE SubName: Full=LPXTG cell wall anchor domain-containing protein {ECO:0000313|EMBL:MBS4209186.1};
GN ORFNames=KHA95_14075 {ECO:0000313|EMBL:MBS4209186.1};
OS Bacillus sp. FJAT-50079.
OC Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=2833577 {ECO:0000313|EMBL:MBS4209186.1, ECO:0000313|Proteomes:UP000678477};
RN [1] {ECO:0000313|EMBL:MBS4209186.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FJAT-50079 {ECO:0000313|EMBL:MBS4209186.1};
RA Liu G.;
RT "Novel Bacillus species.";
RL Submitted (MAY-2021) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted, cell wall
CC {ECO:0000256|ARBA:ARBA00004168}; Peptidoglycan-anchor
CC {ECO:0000256|ARBA:ARBA00004168}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:MBS4209186.1}.
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DR EMBL; JAGYPD010000005; MBS4209186.1; -; Genomic_DNA.
DR RefSeq; WP_213138164.1; NZ_JAGYPD010000005.1.
DR Proteomes; UP000678477; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004622; F:lysophospholipase activity; IEA:TreeGrafter.
DR Gene3D; 3.40.50.1110; SGNH hydrolase; 2.
DR InterPro; IPR051532; Ester_Hydrolysis_Enzymes.
DR InterPro; IPR019931; LPXTG_anchor.
DR InterPro; IPR013830; SGNH_hydro.
DR InterPro; IPR036514; SGNH_hydro_sf.
DR NCBIfam; TIGR01167; LPXTG_anchor; 1.
DR PANTHER; PTHR30383:SF27; SPORE GERMINATION LIPASE LIPC; 1.
DR PANTHER; PTHR30383; THIOESTERASE 1/PROTEASE 1/LYSOPHOSPHOLIPASE L1; 1.
DR Pfam; PF00746; Gram_pos_anchor; 1.
DR Pfam; PF13472; Lipase_GDSL_2; 1.
DR SUPFAM; SSF52266; SGNH hydrolase; 1.
PE 4: Predicted;
KW Cell wall {ECO:0000256|ARBA:ARBA00022512};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Peptidoglycan-anchor {ECO:0000256|ARBA:ARBA00023088};
KW Reference proteome {ECO:0000313|Proteomes:UP000678477};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..28
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 29..680
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5036888408"
FT TRANSMEM 651..670
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 40..118
FT /note="SGNH hydrolase-type esterase"
FT /evidence="ECO:0000259|Pfam:PF13472"
FT DOMAIN 636..674
FT /note="Gram-positive cocci surface proteins LPxTG"
FT /evidence="ECO:0000259|Pfam:PF00746"
FT REGION 583..646
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 585..599
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 622..635
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 680 AA; 72383 MW; E0D16950D59E2F34 CRC64;
MQRVIKRSRA LLLMLVFVLA FAPLSTLANE GKTNTVNYVA LGDSLAAGIL SDNTPSTGYV
GLIKNSLEGN GYEVNVHNAG KSGATSGQVL AGLSEISKLA DADIITISVG ANDILGGLMP
ILSSGINPAD LNKEKLAEVQ QLAEVTMANA KLAADAEDIA KSAVEREVNE IKNAMNNLEV
TGAIEVIKTK IPAEKLPLVQ PTLDNILSNV LTAQTSVGLA LDTYNSAGSL ETVSSELNTA
GAKLNETVTI INSLKTFIPD DLKTLADEIV AQLSDASAKA STAKAAADGA ITAVNVSNEA
KVAAEQAQQA AQLLGDALTK LAAIPGIIGE VGSNTAQILG AIRSVNPTSK IYVMGYYNAL
PYLPAEVQEI MTKPMLFNLN TAISMPTSQF GATFVPVAQL FEGNYQTYLP NQANIHPSAA
GYEALASAFI GAINPSFPKI EDPDPEEPYV KDVELGKELM VNSDELIRII GADVTLLLPN
DLPEGTLLTV TLTSEDALSK AEGLKAFGDA LNFEFQYPEG FKDYEGTFTL MMGYDADSPE
DVDIYYYNEA EGKWESQKGE KNKELQTISI VVTHFSNYGV FAQVDKPDDT PPVDPKDPVQ
DPDDGDDDKT PVPGAKDPGN GSKDDTKKDK KDDKTKHTKK GSLPNTATND YNWLMLGISL
LLTGVAMFLL SRKRRLSINA
//
