ID A0A942Z0C6_9BACI Unreviewed; 729 AA.
AC A0A942Z0C6;
DT 22-FEB-2023, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2023, sequence version 1.
DT 02-APR-2025, entry version 7.
DE SubName: Full=HD family phosphohydrolase {ECO:0000313|EMBL:MBS4217111.1};
GN ORFNames=KHA96_02145 {ECO:0000313|EMBL:MBS4217111.1};
OS Bacillus sp. FJAT-49711.
OC Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=2833585 {ECO:0000313|EMBL:MBS4217111.1, ECO:0000313|Proteomes:UP000678491};
RN [1] {ECO:0000313|EMBL:MBS4217111.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FJAT-49711 {ECO:0000313|EMBL:MBS4217111.1};
RA Liu G.;
RT "Novel Bacillus species.";
RL Submitted (MAY-2021) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:MBS4217111.1}.
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DR EMBL; JAGYPL010000001; MBS4217111.1; -; Genomic_DNA.
DR RefSeq; WP_213127650.1; NZ_JAGYPL010000001.1.
DR Proteomes; UP000678491; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00077; HDc; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR006674; HD_domain.
DR InterPro; IPR006675; HDIG_dom.
DR InterPro; IPR011624; Metal-dep_PHydrolase_7TM_extra.
DR InterPro; IPR011621; Metal-dep_PHydrolase_7TM_intra.
DR InterPro; IPR052722; PgpH_phosphodiesterase.
DR NCBIfam; TIGR00277; HDIG; 1.
DR PANTHER; PTHR36442; CYCLIC-DI-AMP PHOSPHODIESTERASE PGPH; 1.
DR PANTHER; PTHR36442:SF1; CYCLIC-DI-AMP PHOSPHODIESTERASE PGPH; 1.
DR Pfam; PF07698; 7TM-7TMR_HD; 1.
DR Pfam; PF07697; 7TMR-HDED; 1.
DR Pfam; PF01966; HD; 1.
DR SMART; SM00471; HDc; 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR PROSITE; PS51831; HD; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000678491};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..36
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 290..308
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 320..340
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 370..387
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 399..416
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 428..449
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 455..479
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 512..654
FT /note="HD"
FT /evidence="ECO:0000259|PROSITE:PS51831"
SQ SEQUENCE 729 AA; 81653 MW; 1CD6924FF11C9FEB CRC64;
MDFQAYISKI RTFLSYKVFT SIIYCILGIA LFATLYHNVK PETYDIELFS VADKTIRSTK
TVEDEIKTAE AKENAAEQVD KVYVFKKEMA QNRVSLITSI FDFVKDTNNE SSKDVEKNAS
EIKKEEVSAI SLQSRLKQLK TKLTENVSED ITNTISDPIF ITFLQADVEE LQRTKDIVEQ
YVETAMNEQI REDGMEAARK VVADQIKTAG LSNELQTAAI ELGKYAIVPN DLYDPLLTEA
RKKQAMEDVE PVKILQGQII VQEGHLIDRE TYRQLEMLGL LKNNPTIKPI IGLGIFVILV
IGSIYIYFSR LSTSEDKKQS YLLLSSLIFI CSVIIMKIIG LIEGDNLNKV AYIFPAAMAP
MLIKTMINER LALIMTIILA SCGSIVFHDG ISDTINIEIA VYILFSGLAG VLFVSAKNER
SHILRAGLLV SCINLLLIFF LLLIGGGQFT LTEYFYFGLF SVMSGILSSV FTIGLLPFFE
AGFGILSTMR LIELSNPNHP LLKKLLTETP GTYHHSVMVA NLAEAACEAI GANGLLARVG
CYYHDVGKTK RPPFFIENQM NIENPHDRLP AETSKDIIIS HAADGAKELR KHKLPKEIVD
IAEQHHGTSL LKYFYFKAKK LNDDTPEIDY RYPGPKPQTR EAAVISLADS VEAAVRSMAN
PTPGEIRSLV HHISQDKILD GQFNECDLTL KEIELVKTRF CETLNGIFHS RIEYPDLKQQ
KVIGSDTAN
//
