ID A0A949K101_9FIRM Unreviewed; 638 AA.
AC A0A949K101;
DT 22-FEB-2023, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2023, sequence version 1.
DT 28-JAN-2026, entry version 15.
DE SubName: Full=Selenocysteine-specific translation elongation factor {ECO:0000313|EMBL:MBU9738923.1};
GN Name=selB {ECO:0000313|EMBL:MBU9738923.1};
GN ORFNames=KTH89_20515 {ECO:0000313|EMBL:MBU9738923.1};
OS Diplocloster agilis.
OC Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
OC Lachnospiraceae; Diplocloster.
OX NCBI_TaxID=2850323 {ECO:0000313|EMBL:MBU9738923.1, ECO:0000313|Proteomes:UP000712157};
RN [1] {ECO:0000313|EMBL:MBU9738923.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ASD5720 {ECO:0000313|EMBL:MBU9738923.1};
RA Chaplin A.V., Sokolova S.R., Pikina A.P., Korzhanova M., Belova V.,
RA Korostin D., Efimov B.A.;
RT "Description of novel taxa of the family Lachnospiraceae.";
RL Submitted (JUN-2021) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:MBU9738923.1}.
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DR EMBL; JAHQCW010000045; MBU9738923.1; -; Genomic_DNA.
DR RefSeq; WP_238722929.1; NZ_JAHQCW010000045.1.
DR AlphaFoldDB; A0A949K101; -.
DR Proteomes; UP000712157; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:TreeGrafter.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0001514; P:selenocysteine incorporation; IEA:InterPro.
DR CDD; cd04171; SelB; 1.
DR CDD; cd15491; selB_III; 1.
DR Gene3D; 1.10.10.2770; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR057335; Beta-barrel_SelB.
DR InterPro; IPR050055; EF-Tu_GTPase.
DR InterPro; IPR015190; Elong_fac_SelB-wing-hlx_typ-2.
DR InterPro; IPR031157; G_TR_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR015191; SelB_WHD4.
DR InterPro; IPR005225; Small_GTP-bd.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR InterPro; IPR004535; Transl_elong_SelB.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR00475; selB; 1.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR43721:SF22; ELONGATION FACTOR TU, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43721; ELONGATION FACTOR TU-RELATED; 1.
DR Pfam; PF25461; Beta-barrel_SelB; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF09106; WHD_2nd_SelB; 1.
DR Pfam; PF09107; WHD_3rd_SelB; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SUPFAM; SSF50465; EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 2.
DR PROSITE; PS00301; G_TR_1; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Elongation factor {ECO:0000313|EMBL:MBU9738923.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000712157}.
FT DOMAIN 1..173
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
SQ SEQUENCE 638 AA; 71841 MW; 300BDB4F75A15A28 CRC64;
MTYWTVGTAG HIDHGKTALI KALTGRDTDR LEEEKKRGIT IDLGFTYFDL PGGDRVGIID
VPGHERFIGN MLAGVSGIDL VLLVIAADEG VMPQTVEHVE ILEQLGVTRG MIVLSKCDLV
DRQLRDLVTE DVRQRLSGSC FANAPMAYVS AVTGEGIPDL AILMERLLRQ GPLFRNVSTF
PRLFIDRIFQ KKGLGTIAAG TLLSGEIARE DRLFLYPQML PCRIRGVQVH GQEMEKASAG
QRTAVNLPDI VCSQIRRGTV IAREGALRNT RLLDVRIHMC RHTKRRLLNR TRLHLYIGAA
KLLCRAVLMD TEELAAGESG YAQLVLEEDL AVLKGDRFIL RFYSPLETIG GGEILDPNPV
KKHRYRPKDL EEFRREEAAD FPQEILMYIQ KQPHGFIVKQ ELAAAFGADE SSIAYAAAVL
EKEEHLVSLQ GKTKTFLYER ERYEEQISRT EAYLSRFHKE RPYRWGIGKA QLRTGCDPWM
TQEFCDAFCQ TASDQGRLQT GAQLVRLKNY QVPCDGTYQK VTDILFENLT AGGMDFVRLR
DMDFGGIAEQ TVLDICADEL EKGKLYKLTQ DCYTLAELYE DACAKISALL RQNGKITVTE
LRDLFGTNRR SIRILLEDLD SRGITRKDGK ESERVSAL
//
