ID A0A9B0TQV4_CHRAS Unreviewed; 573 AA.
AC A0A9B0TQV4;
DT 03-MAY-2023, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2023, sequence version 1.
DT 10-JUN-2026, entry version 16.
DE SubName: Full=Synapsin-3 isoform X1 {ECO:0000313|RefSeq:XP_006865300.1};
GN Name=SYN3 {ECO:0000313|RefSeq:XP_006865300.1};
OS Chrysochloris asiatica (Cape golden mole).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Afrosoricida; Chrysochloridae; Chrysochlorinae;
OC Chrysochloris.
OX NCBI_TaxID=185453 {ECO:0000313|Proteomes:UP000504623, ECO:0000313|RefSeq:XP_006865300.1};
RN [1] {ECO:0000313|RefSeq:XP_006865300.1}
RP IDENTIFICATION.
RC TISSUE=Spleen {ECO:0000313|RefSeq:XP_006865300.1};
RG RefSeq;
RL Submitted (JAN-2026) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle, synaptic
CC vesicle {ECO:0000256|ARBA:ARBA00004234}.
CC -!- SIMILARITY: Belongs to the synapsin family.
CC {ECO:0000256|ARBA:ARBA00008243}.
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DR RefSeq; XP_006865300.1; XM_006865238.1.
DR AlphaFoldDB; A0A9B0TQV4; -.
DR GeneID; 102814064; -.
DR CTD; 8224; -.
DR OrthoDB; 10249572at2759; -.
DR Proteomes; UP000504623; Unplaced.
DR GO; GO:0030672; C:synaptic vesicle membrane; IEA:TreeGrafter.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0007269; P:neurotransmitter secretion; IEA:InterPro.
DR FunFam; 3.30.1490.20:FF:000008; Synapsin I; 1.
DR FunFam; 3.30.470.20:FF:000042; Synapsin III; 1.
DR FunFam; 3.40.50.20:FF:000008; Synapsin III; 1.
DR Gene3D; 3.40.50.20; -; 1.
DR Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR InterPro; IPR013815; ATP_grasp_subdomain_1.
DR InterPro; IPR016185; PreATP-grasp_dom_sf.
DR InterPro; IPR001359; Synapsin.
DR InterPro; IPR020898; Synapsin_ATP-bd_dom.
DR InterPro; IPR019735; Synapsin_CS.
DR InterPro; IPR019736; Synapsin_P_site.
DR InterPro; IPR020897; Synapsin_pre-ATP-grasp_dom.
DR PANTHER; PTHR10841; SYNAPSIN; 1.
DR PANTHER; PTHR10841:SF27; SYNAPSIN-3; 1.
DR Pfam; PF02078; Synapsin; 1.
DR Pfam; PF02750; Synapsin_C; 1.
DR Pfam; PF10581; Synapsin_N; 1.
DR PRINTS; PR01368; SYNAPSIN.
DR SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR SUPFAM; SSF52440; PreATP-grasp domain; 1.
DR PROSITE; PS00415; SYNAPSIN_1; 1.
DR PROSITE; PS00416; SYNAPSIN_2; 1.
PE 3: Inferred from homology;
KW Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000504623};
KW Synapse {ECO:0000256|ARBA:ARBA00023018}.
FT DOMAIN 88..190
FT /note="Synapsin pre-ATP-grasp"
FT /evidence="ECO:0000259|Pfam:PF02078"
FT DOMAIN 192..394
FT /note="Synapsin ATP-binding"
FT /evidence="ECO:0000259|Pfam:PF02750"
FT REGION 19..83
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 403..560
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 30..39
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 46..65
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 419..432
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 435..484
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 487..505
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 530..549
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 573 AA; 62626 MW; 9026F3713A27A8C7 CRC64;
MNFLRRRLSD SSFVANLPNG YMTDLQRPDS SSSSPASPAM ERRAQPLAAS FSSPGSSLFS
SFSSAMKPTS QAPTGLVEPP APSTPVIQRP RVLLVIDNAY TDWAKYFHGK KVNGEIEIRV
EQAEFSELNL AAYVTGGCMV DMQVVRNGTK LVSRSFKPDF ILVRQHAYSM ALGEDYRSLV
IGLQYGGLPS VNSLYSVYNF CSKPWVFSQL IKIFHSLGPE KFPLVEQTFF PNHKPMLTAP
HFPVVVKLGH AHAGMGKIKV ETQHDFQDIT SVIAMAKTYA TTEAFIDSKY DIRIQKIGSN
YKAYMRTSIS GNWKANTGSA MLEQVAMTER YRLWVDSCSE MFGGLDICAV KAVHSKDGRD
YIIEVMDSSM PLIGEHVEED KQLMADLVVS KMSQLLMPGG MVPSPLRPWA PQMKPAKSPG
QTQLGQPQSR PPTQGGPRQA QSSQPPRSGS PSQQRLSPQG QQPLSPQSGS PQQQRSPGSP
QLPRASGGSS PNQASKPGFS SQSRPPVQGR SSSQQSEEAK KSAPPHPHLN KSQSLTNSLG
TSDTAQRGTP SEDEAKAETI RNLRKSFASL FSD
//
